Tlhaloso ea Clinical Trial Terminology e hlalositsoe
Litekong tsa meriana ea ramatiki ea lefu la rheumatoid, mekhoa e tloaelehileng e sebelisoa ho bapisa katleho ea meriana ea ramatiki kapa phekolo ea ramatiki, kapa ho bapisa teko e 'ngoe ho e' ngoe. Mekhoa e tsejoang e le "American College of Rheumatology", e leng tekanyo e sebelisoang hoo e batlang e le liphuputso tsohle tse hatisitsoeng tse shebileng katleho ea phekolo bakeng sa mefuta eohle ea maloetse a rheumatic .
ACR20 e ne e le setulo sa pele sa litekanyetso tse thehiloeng, se lateloa ke ACR50 le ACR70.
Tšebeliso ea Lintlha tsa ACR
Litekanyetso tsa ACR li sebelisetsoa ho hlahloba le ho theha ntlafatso ea litekanyetso tsa litekanyetso kapa tse ruruhileng hammoho le ntlafatso ho tse tharo tsa litekanyo tse hlano tse latelang:
- Mokhoa o motle oa sekhahla: Ho na le ho ruruha ho bokae ho lintlheng tsa hao joalokaha ho thehiloe ke protheine ea C-reactive kapa rate sedimentation.
- Tlhahlobo ea bakuli: U bona joang tsoelo-pele ea hau le karabelo ea kalafo.
- Tlhahlobo ea ngaka: Seo ngaka ea hau e se bonang tsoelo-pele ea hau le karabelo ea kalafo.
- Bothata ba bohloko: U na le mahlomola a mangata mantsoeng a hao letsatsi le leng le le leng.
- Leqephe la lipotso la bokooa / ts'ebetsong: Ho na le ramatiki ea mafu a mangata e sitisang matla a hau a ho etsa mesebetsi ea hau ea letsatsi le letsatsi.
Mekhoa ea ACR e ka boela ea sebelisoa ho thusa lingaka hore li atlehe ho fumana hore na litlhare tsa hau li sebetsa joang ho ntlafatsa matšoao a hau a lefu la masapo, le hoja a atisa ho sebelisoa bakeng sa liteko tsa tleliniki.
Ho Utloisisa Seo ACR20, ACR50, le ACR70 ba se bonts'ang litlamong tsa meriana
Litlhahlobo tsa meriana ea bongaka li tlaleha karolo ea palo ea barupeluoa ba ithutoang ba fihletseng ACR20, ACR50 le ACR70. Ka mohlala, haeba thuto e tlalehile hore bakuli ba 55 lekholong ba fihlile ACR20, seo se bolela hore karolo ea 55 lekholong ea bakuli boithutong e finyelletse liphetoho tse 20 lekholong la litekanyetso kapa tse fokolang, hammoho le liphetoho tse 20 lekholong ho tse tharo tse ling tse hlano.
Haeba teko ea lits'ebeletso tsa meriana e tlaleha hore bakuli ba 40 lekholong ba fihlile ACR50, seo se bolela hore karolo ea 40 lekholong ea bakuli ba ithutoeng e fihletsoe ke liphetoho tse 50 lekholong la litekanyetso tsa litlhapi kapa tse ruruhileng, hammoho le ntlafatso ea karolo ea 50 lekholong ho tse tharo tse ling tse hlano. Ho joalo le ho ACR70, feela ka karolo ea 70 lekholong ea ntlafatso. Bakeng sa bakuli ho hlahlojoa ka mekhoa ea ACR, e tlameha ebe ba qetile nyeoe ea kliniki.
ACR20 Na FDA e amoheleha
Tsamaiso ea US Food and Drug Administration (FDA) e khothalelitse tšebeliso ea ACR20 e le tekanyo ea ho khetha bakeng sa liteko tsa meriana ea lithethefatsi tse sebelisetsoang ho phekola ramatiki ea lefuba. Ts'ehetso ena e ile ea lebisa tlhobelisong e sebelisoang ea ACR20 litekong tsa meriana. Hangata ho thoe ke ACR20 feela hobane e hloka bonyane liphetoho tse 20 lekholong lits'ebetsong tse ka holimo.
Lisebelisoa:
> Felson DT, Anderson JJ, Boers M, le al. K'holejini ea Amerika ea Rheumatology Preliminary Tlhaloso ea Ntlafatso ea Ramatiki ea Ramatiki. Ramatiki le Rheumatism. 1995; 38: 727-735. doi: 10.1002 / art.1780380602.
> Felson DT, LaValley MP. ACR20 le Ho Hlalosa Sepheo sa Tlhaselo ea Likarabo ho Rheumatic Diseases: Ho na le Letlotlo le Letle haholo. Pheputso ea ramatiki le Therapy . 2014; 16 (1): 101. doi: 10.1186 / ar4428.
Johns Hopkins Setsi sa Ramatiki. Mekhoa ea ho hlahloba ACR: Tlhaloso ea ACR ea Ntlafatso Tlhahlobo ea RA. Johns Hopkins Medicine. E ntlafalitsoe ka la 16 August, 2017.
Rocha K. ACR Score: Ho lekanya Rheumatoid Ramatiki. Rheumatoid Arthritis Support Network. E hlalositsoe ka la 22 March, 2017.