Phuputso e fana ka ts'oaetso ea boithaopo
Matšoao a Vogt-Koyanagi-Harada syndrome (VKH) a na le lefu la kelello, leihlo, tsebe le matšoao a letlalo. Lipatlisiso li fana ka maikutlo a hore e ka ba ka lebaka la karabelo ea 'mele eo' mele o hlaselang eona lisele tse phetseng hantle tse nang le melanine ea pigment. VKH syndrome ha e khutsufatse nako ea bophelo, empa liphetoho tsa mahlo le letlalo li ka 'na tsa hlaha.
Ha ho tsejoe hore na kankere ea Vogt-Koyanagi-Harada e etsahala hangata lefatšeng lohle.
E etsahala khafetsa ho batho ba Asia, Maamerika, Latin America, kapa Bochabela bo Hare. Litlaleho tse hatisitsoeng tsa VKH syndrome li bontša hore e etsahala khafetsa ho basali le ho feta ho banna, 'me matšoao a eona a ka' na a qala ka lilemo leha e le life.
Matšoao
Pele lefu la lefu la Vogt-Koyanagi-Harada le qala, hangata batho ba na le matšoao a kang hlooho, li-vertigo, ho nyekeloa ke pelo, molala o thata, ho hlatsa , le feberu e tlase-tlaase matsatsi a seng makae. Matšoao ana ha a hlake ho VKH syndrome 'me a ka fumanoa e le tšoaetso ea kokoana-hloko kapa feberu . Seo se khethollang VKH syndrome ho tsoa ho "feberu" ke tšimoloho ea matšoao a mahlo a kang pono e potlakileng ea pono, bohloko le kutloisiso ea leseling. Ka tloaelo, VKH syndrome e na le likarolo tse tharo: karolo ea meningoencephalitis, karolo ea ophthalmic-auditory, le phase de convalescent.
Nakong ea meningoencephalitis , matšoao a kang bofokoli bo fokolang ba mesifa, hlooho, ho lahleheloa ha mesifa ka lehlakoreng le leng la 'mele (hemiparesis kapa hemiplegia), bohloko bo kopantsoeng (dysarthria),' me ho thata ho bua puo kapa ho utloisisa (aphasia).
Mothong ophthalmic-auditory , matšoao a kang pono e fosahetseng, bohloko le mahlo a ho halefa ka lebaka la ho ruruha ha iris (iridocyclitis) le uvea (uveitis) e etsahala. Matšoao a lichelete a ka 'na a kenyelletsa bothata ba ho utloa, ho lla litsebe (tinnitus), kapa molichaba.
Karolong ea convalescent , matšoao a letlalo a kang a khanyang kapa a masoeu a mmala ka moriri, lintši, kapa eyelashes (poliosis), likhahla tse khanyang kapa tse tšoeu tsa letlalo (vitiligo), le ho lahleheloa ke moriri (alopecia).
Hangata matšoao a letlalo a qala libeke tse 'maloa kapa likhoeli kamora' pono le matšoao a utloahalang a qala.
Tsejoa
Hobane lefu la Vogt-Koyanagi-Harada le sa tloaelehang, hangata lefu lena le nepahetseng le hloka ho buisana le litsebi. Ha ho na teko e tobileng ea lefu lena, kahoo lefu lena le thehiloe matšoao a hlahang hammoho le liphello tsa teko. Setsebi sa methapo ea mafu se tla etsa hore ho be le sekheo sa lumbar ho hlahloba cerebrospinal fluid (CSF) bakeng sa liphetoho tse hlahang ho VKH syndrome. Setsebi sa likokoana-hloko se tla etsa tlhahlobo e khethehileng ea mahlo hore a batle li-uveitis. Dermatologist e tla nka sampho ea letlalo ka khoeli e le 'ngoe ka mor'a hore matšoao a mahlo a qale ho hlahloba liphetoho tsa VKH syndrome, tse kang ho haelloa ke pigment (melanin) leseling kapa litšoeu tse tšoeu tsa letlalo tse teng.
The American Uveitis Society e khothalletsa hore ho be le mehato e meraro ho tsena tse 4 ho netefatsa hore na lefu la Vogt-Koyanagi-Harada le fumanoa joang:
- iridocyclitis mahlong a mabeli, le uveitis
- matšoao a kelello kapa liphetoho tse hlahang ho CSF
- matšoao a letlalo a poliosis, vitiligo, kapa alopecia
Phekolo
Ho fokotsa ho ruruha mahlong, corticosteroids e kang prednisone e fanoa. Haeba sena se sa sebetse hantle, lithethefatsi tsa immunosuppressant tse kang azathioprine (Imuran) kapa cyclophosphamide (Cytoxan, Neosar) li ka sebelisoa.
Matšoao a letlalo a tšoaroa ka tsela eo vitiligo e tšoaroang ka eona, e ka akarelletsang phototherapy, corticosteroids, kapa mafura a moriana.
Ho hlahlojoa le ho phekoloa ha lefu la Vogt-Koyanagi-Harada ho thusa ho thibela liphetoho tsa ka ho sa feleng tse kang glaucoma le likhalase. Liphetoho tsa letlalo li ka ba teng ka ho sa feleng, esita le kalafo, empa ho utloahala hangata ho tsosolosoa ho batho ba bangata.
> Mehloli:
Choczaj-Kukula, A. (2005). Lefu la Vogt-Koyanagi-Harada. eMedicine, fihletsoe ho http://www.emedicine.com/derm/topic739.htm
Bala, RW (2003). American Uveitis Society: Maloetse a Vogt-Koyanagi-Harada.