Kamoo karabo ea khatello ea maikutlo e amang matšoao a hau kateng
Mohlomong u kile ua fumana kamano pakeng tsa IBS le khatello ea maikutlo. Sena se na le lintho tse ngata tseo re lokelang ho li etsa ka tsela eo 'mele ea rona e arabelang ka eona liphetohong tsa ka hare kapa tsa ka ntle. Tlhaloso ena ea khatello ea maikutlo, eo hape e tsejoang e le karabo ea ntoa kapa ea sefofane, e bonahala e hlahile e le ho re lumella ho arabela maemong a sokelang bophelo ka tsela e tla eketsa menyetla ea rona ea ho phela.
Khatello ea khatello ke mokhoa o rarahaneng. E kenyelletsa mekhoa ea rona ea methapo le ea endocrine 'me e susumetsa liphetoho mekhoeng e sa tšoaneng ea' mele, ho kenyelletsa khatello ea mali, lebelo la pelo, tsitsipano ea mesifa le ho sebetsana le 'mele. Ke liphetoho tse sebetsanang le mefuta ea matsoho tse kopanyang likarabo tsa khatello ea maikutlo le IBS hammoho.
Boitsebiso ba Brain-Gut
Ka lebaka la mohatelli ea nahannoeng (ka ntle kapa ka hare), likarolo tse fapa-fapaneng tsa boko li qala ho buisana, ho akarelletsa le cortex e utloahalang, thalamus, le boko ba boko. Ts'ebetso ena e ntšetsa pele karabo ka litsela tse peli tse kholo tsa 'mele. Ntho ea pele ke hypothalamic-pituitary-adrenal axis, e leng se hlahisang keketseho ea liphiri tsa hormone, haholo-holo hormone cortisol. Tsela ea bobeli ke tsamaiso ea methapo ea boithaopo , e hlahisang adrenaline (epinephrine) le noradrenaline (norepinephrine) e bakang tsamaiso ea pelo, ea mesifa le ea ho ja lijo.
Litsela tsena tse peli li amana ka ho toba le methapo ea methapo e fumanoang ka maling, a tsejoang e le tsamaiso ea methapo ea enteric. Ts'ebetso ena, e qalang ka khatello ea maikutlo, e lateloa ke karabo ea boko, e bakiloeng ke ho tsosoa ha litsela tse peli ho ea marung, e bontša bohlokoa ba ho sheba khatello ea maikutlo ho leka ho utloisisa ho se sebetse hoo ho bonahalang e le matšoao a IBS.
Liphetoho tsa 'Meleng Khatellong ea Khatello ea Kelello
Khatello ea khatello ea maikutlo e baka liphetoho tse latelang tsa 'mele:
- Lebelo la pelo lea eketseha
- Ho hema ho eketsehileng
- Ho ferekana ha mesifa
- Ho thibela sesole sa 'mele
- Ho lieha ho ntša mpa
- Eketsa ka lebelo la li-colonic contractions
- Ho phutholoha ha mesifa ea senya
Lipatlisiso
E le ho leka ho fumana phekolo e atlehang bakeng sa matšoao a IBS, bafuputsi ba 'nile ba batlisisa lintho tse sa tšoaneng tse lokolloa nakong ea karabo ea khatello ea maikutlo. Ntho e 'ngoe e bonahalang e e-na le bohlokoa bo tebileng mohatsong oa khatello ke corticotropin-release-factor (CRF). CRF ke lelapa la li-peptide (limolek'hule tse amanang le amino acid) tse fumanoang bobeli le bokoti. Bokong, li-receptor tsa CRF li fumaneha libakeng tse amanang le ts'ebetso, maikutlo le tsamaiso ea methapo ea boithaopo. Metsing, CRF liketso ka har'a kolone ho eketsa sephiri sa metsi le metsi, li ama lebelo la lik'hemik'hale tsa mokokotlo ( motility ), 'me li bonahala li amana le phihlelo ea bohloko ba mpeng . Ho na le tšepo ea hore kutloisiso e ntlafetseng ea karolo ea CRF e tla lebisa ho ntlafatsong ea ho ntlafatsa meriana e lebisang matšoao a IBS.
Lisebelisoa:
Benson, H. Relaxation Response (2000). New York: HarperTorch.
Monnikes, H., et.al. "Boikarabello ba khatello ea kelello mathateng a ts'oaetso ea masapo. Bopaki ba liphetoho tse bakoang ke khatello ea kelello ka masapo a moriri motility le kutloisiso." Litlhaku tsa Digestive 2001 19: 201-211.
Mayer, EA, et.al. "Khatello ea Kelello le Tlhahiso ea Moriana" American Journal of Physiology-Maloetse le Mafu Physiology 2001 4: G519-G524.
Tache, Y. "Khatello ea kelello le Irritable Bowel Syndrome: Ho senya Molao" Motheo oa Machaba oa Tlhaloso ea Maqakabetsi ea Mesebetsi ea Mesebetsi ea Mesebetsi. 2007.