Estrogen ke hormone e phethang karolo ea bohlokoa bophelong bo botle ba basali, ho akarelletsa le bophelo bo botle ba matsoele le bone. A re ithute ka karolo ea li-estrogen e bapalang bophelo bo botle ba basali le kamoo ho felisoa ha hormone ena ho fokotsang kotsi ea ho khutlela kankere ea matsoele ho basali ba bang.
Estrogen ke hormone e hlahisoang ke mahe a mosali ho fihlela a fihla moeeng. Ha a qeta nako ea ho ilela khoeli, e hlalosoang e le likhoeli tse 12 kamora ho qetela ha mosali a ea khoeling, mae a bomme a khaotsa ho etsa estrogen.
Ho haelloa ke estrogen ke hona ho bakang matšoao a mangata a ho khaotsa ho ipolaea, joalo ka ho chesa ho chesang le ho omella ka botšehaling.
Phekolo ea Estrogen?
Basali ba bang ba nka phekolo ea li-hormone, hangata e ngotsoe ka nako e telele kapa nakong ea pele ea ho ikhula, ho fokotsa matšoao a tšoaroang ke menopausal, haholo-holo ho chesa. Phekolo ea hormone e na le li-estrogen le progesterone kapa estrogen feela.
Haeba mosali a se na popelo-ka mohlala, haeba a e-na le hysterectomy -than a ka 'na a nka estrogen therapy (ET) a le mong. Haeba mosali a e-na le sebete, o lokela ho nka progesterone ho phaella ho estrogen. Lebaka ke hore phekolo ea estrogen e ka lebisa ho teteaneng ha lesela la sebete le ka bakang kankere ea endometrial. Ho eketsa progesterone ho na le phello ena.
Ke habohlokoa ho tseba hore ho ea ka US Federal Drug Administration (FDA), phekolo ea hormone e hanyetsanoa ho mosali leha e le ofe ea nang le kankere ea matsoele ea hona joale, histori ea kankere ea matsoele kapa kankere ea matsoele.
Kamoo Estrogen e Amanang le Kankere ea Bokhachane
Ho ea ka American Cancer Society, hoo e ka bang tse peli ho tse tharo tsa kankere ea matsoele ke li-hormone receptor-positive. Sena se bolela hore lisele tsa kankere li na le li-receptors bakeng sa leha e le efe kapa li-hormone-estrogen le progesterone.
Estrogen e susumelletsa ho hōla ha kankere ea matsoele e fumanoang ke estrogen-receptor-positive.
Ke ka lebaka leo phekolo ea hormone ea menopausal e hanyetsanang le basali ba nang le kankere ea matsoele kapa histori ea kankere ea matsoele, e le hore ba se ke ba eketsa kotsi ea mosali ea ho khutlela kankere ea matsoele.
Estrogen Suppression Therapy
Mefuta e mengata ea phekolo ea li-hormone bakeng sa kankere ea matsoele, joaloka methapo ea estrogen-receptor kapa aromatase inhibitors, maemong a tlaase a estrogen kapa ho emisa estrogen ho etsa liphatsa tsa kankere ea matsoele. Kalafo ea mofuta ona e thusa li-cancer tsa letsoele tse nang le tumello ea hormone, empa ha e thuse bakuli ba nang le li-tumor tse amohelang li-hormone (e leng ER-le PR-negative).
Estrogen e Amana le Bophelo bo Botle ba Lesapo
Matšoao a nang le bophelo bo botle ba estrogen 'meleng oa hau e haha le ho boloka masapo a matla. Leha ho le joalo, haeba u e-na le chemotherapy kapa u nka moriana oa khatello ea estrogen ka mor'a hore u phekoloe kankere ea matsoele, maemo a hao a estrogen e tla ba a tlaase. Itebela masapo a hao ka ho utloisisa hore na estrogen e ama masapo a hau joang.
Lisebelisoa:
Mokhatlo oa Kankere oa Amerika. Kankere ea matsoele: phekolo ea hormone bakeng sa kankere ea matsoele . La 14 Mphalane, 2015.
Mokhatlo oa North American Menopause Society. (2014). Boitšoaro ba ho ipeha ha meriana: Tataiso ea ngaka ea ngaka, 5 th . Mayfield Heights, OH: The North American Menopause Society.