Ho na le kankere ea matsoele ea meriana ea lefuba e fapaneng joang ho feta tse ling tsa kankere ea matsoele?
Medullary carcinoma ea sefuba ke mofuta o sa tloaelehang oa kankere ea matsoele. Ke mofuta oa ductal carcinoma (IDC) e hlaselang 'me e e nka lebitso ho tloha' mala oa eona, o haufi le 'mala oa likopi tsa boko, kapa medulla. E qala ka maqeba a hao a lebese, le lisele tse khōlō tsa kankere tse shebahalang li fapane haholo le lisele tse phetseng hantle.
Medullary carcinoma hase lefu le tloaelehileng.
Medullary carcinoma e etsa karolo ea 3 lekholong feela ho karolo ea 5 lekholong ea lik'hemik'hale tsohle tsa matsoele. Ho ka ba thata ho khetholla ho tswa ho ductal carcinoma 'me ho na le lik'hemik'hale tse nang le likarolo tse ling empa e se likarolo tsohle tsa medullary carcinoma. Ka lebaka la sena se etsahalang, ka linako tse ling lingaka li tšoara medullary carcinoma ka tsela e mabifi, mohlomong, ho feta kamoo e hlokahalang, e fane ka bopaki bo nepahetseng. E tloaelehile haholo ho basali ba lilemong tsa bo-40 le bo-50.
Ponahalo
Lisele tsa Medullary carcinoma li atisa ho ba le moeli o hlakileng pakeng tsa hlahala le lisele tse phetseng hantle haufi le tsona - li fokola haholo ho feta tse ling tsa lisele tsa kankere ea matsoele. Tlas'a microscope, lisele li le khōlō ebile ha li sa tloaeleha ebile li bonahala li le mabifi, empa li atisa ho se be mabifi ha li shebahala.
Hangata ho na le lisele tse ngata tsa 'mele tsa ho itšireletsa mafung (tse kang li-lymphocytes) metseng ea li-tumor tsena, ho fana ka maikutlo a hore tsamaiso ea' mele ea ho itšireletsa mafung e sebetsa ho loantša hlahala.
Ha kankere ea matsoele e na le ponahalo ea medullary carcinoma empa ha e lumellane le litekanyetso tsohle, u ka 'na ua utloa tumor ea hao e bitsoa "atypical medullary carcinoma." Lik'hemik'hale tsena tsa kankere li atisa ho tšoaroa joaloka tse ling tsa kankere ea matsoele, ka mantsoe a mang, ka mabifi.
Matšoao le Matšoao
Medullary carcinoma ea sefuba e ka 'na ea se ke ea ikutloa e le lesapo ka linako tsohle, empa ho e-na le hoo, e le sebaka se teteaneng sa lisebelisoa tsa matsoele.
E ka qala ho tsejoa e le bohloko, khubelu, kapa ho ruruha sefuba sa hau. Kaha lisele tsa medullary carcinoma li kholo 'me li rata ho lula hammoho le ho atolosa libakeng tse le' ngoe, hlahala e ka 'na ea ikutloa eka e boreleli, joaloka cyst ea matsoele . Lena ke le leng la mabaka a bohlokoa hore ho be le lesapo le leng le le leng ka har'a letsoele la hao, esita le haeba le ikutloa joaloka cyst e bonolo.
Liteko tsa ho Hlahloba
Meriana ea matsoele ea Medullary hase kamehla e hlahisang mammogram 'me e atisa ho fumanoa pele ha motho e mong a ikutloa a le lesoba. Sefuba sa ultrasound se ka etsoa hape. Tsela e le 'ngoe feela ea ho khetholla medullary carcinoma ho tsoa mefuta e meng ea kankere ea matsoele ke ka ho hlasela. Hangata sampuli ea mahlaseli e nkiloe ke ho buoa ho bulehileng kapa ho otloloha ka matsoele .
Litlhare
Boholo ba meriana ea meriana e nyenyane mme e ka phekoloa habonolo ka ho buuoa. Ha ba na menyetla e mengata ea ho e fetisetsa ho li-lymph nodes, 'me lingaka tse ling li nka ho buuoa feela ho ba phekolo e lekaneng bakeng sa lihlahala tsena (boholo ba tsona li ka tlaase ho 1 cm ka boholo.) Kalafo e ka kenyelletsa:
- Phekolo : Ho buuoa ho batho ba bangata ba nang le mofuta ona oa kankere ea matsoele 'me e ka ba lumpectomy kapa mastectomy , ho itšetlehile ka sebaka sa hlahala le lithahasello tsa botho.
- Chemotherapy : Kaha boholo ba lihlahala tsena li nyenyane 'me hangata ha li jele li-lymph nodes, chemotherapy e atisa ho hlokahala feela bakeng sa lihlahala tse khōloanyane ho feta bolelele ba lisenthimithara. Seo se boletse hore boholo ba lihlahala tsena li kopana - li na le litšobotsi - tsa mefuta e meng ea kankere ea matsoele, ka hona e ka tšoaroa ka mabifi.
- Phekolo ea meriana : Hape, phekolo ea radiation e sebelisoa hangata ho feta mefuta e meng ea kankere ea matsoele, empa e ka sebelisoa maemong a mang ka bomong.
- Phekolo ea Hormone : Phekolo ea Hormone e boetse e sebelisoa hangata ka medullary carcinoma, kaha boholo ba li-tumor ke li-hormone receptor tse mpe. Phuputsong e 'ngoe, karolo ea 68 lekholong ea lihlahala tsena e ne e le mpe bakeng sa li-receptor tsa estrogen le karolo ea 86 lekholong e ne e le mpe bakeng sa li-receptor tsa progesterone.
- Herceptin e sebelisoa ka seoelo ka mofuta ona oa kankere kaha boholo ba lihlahala tsena ke HER2 tse mpe. Phuputsong e le 'ngoe ho feta karolo ea 80 lekholong ea lihlahala e ne e le mpe bakeng sa li-receptor tsa HER2.
Ho phatloha
Medullary carcinoma e atisa ho ba le lisele tse phahameng tse hlahelang tse sebetsang ka mokhoa o tsoelang pele. Ha ho bonolo ho hasana ho lymph nodes ho feta tse ling tsa kankere ea matsoele 'me ka kakaretso ba na le mokhoa o motle oa ho bua. Phuputsong e le 'ngoe e kholo, palo ea batho ba phelang ka lilemo tse 2 e ne e le karolo ea 98,2 lekholong. Lebelo la ho boela ho feta mona le lona le tlaase haholo ha le bapisoa le mefuta e meng ea kankere ea matsoele.
Lisebelisoa:
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Dieci, M., Orvieto, E., Dominici, M., Conte, P., And V. Guarneri. Li-subtypes tsa kankere ea matsoele e tloaelehileng: histological, molecular, le tse khethehileng tsa kliniki. Oncologist . 2014. 19 (8): 805-13.
Lim, S., Park, S., Park, H., Hur, M., Oh, S., le Y. Suh. Karolo ea Boipiletso ea Chemotherapy ea Adjuvant ka Node-E mpe (NO), Tlhaloso e 'Nete (TN), Medullary Kankere ea Lebese (MBC) ho baahi ba Korea. PLO E 'ngoe . 2015. 10 (11): e0140208.
Shokouh, T., Eztollah, A., le P. Barand. Likamano pakeng tsa Ki67, HER2 / neu, p53, ER, le boemo ba PR le likamano tsa bona le tumor grade le ho kenya letsoho ho Breast Carcinoma Subtypes: Retrospective-Observational Analytical Study. Meriana . 2015. 94 (3): e1359.