Melao ea 'mele ea' mele ea Boitšoaro ba 'Mele e le Likarabo tsa Pele ho Tšoaetso
Li-neutrophils, tse tsejoang hape e le neurocytes, ke mofuta oa sele e tšoeu ea mali e bohareng ba tsamaiso ea rona ea 'mele ea ho itšireletsa mafung. E le karolo ea tšireletso ea rona ea ho itšireletsa mafung , li-neutrophils li sebetsa joaloka ba arabelang molaetsa oa pele ho tšoaetso, libaktheria tse hlaselang, likokoana-hloko le likokoana-hloko tse ling.
Li-neutrophils li ka boela tsa bitsoa phagocytes ( phago- e bolelang ho ja le -e leng moelelo oa sele) ha li ntse li sireletsa 'mele ka ho noa likokoana-hloko tse hlaselang.
Li hlahisoa mokong oa masapo le tlaleho ea likarolo tse 50 ho ea ho tse 70 tsa lisele tsa hao tse tšoeu tsa mali.
Seo Neutrophils e se Etsang
Joaloka sele ea ho itšireletsa mafung, li-neutrophils li na le motility e phahameng (e bolelang bokhoni ba ho falla ka boithatelo) 'me ba khonne ho potoloha moemeli ea nang le tšoaetso ho bolaea. Ntle le ho noa likokoana-hloko, li-neutrophils li ka lokolla lisebelisoa tsa cytotoxic (li-cell-killing) tse fokolisang lihloliloeng ka ho toba.
Li-neutrophils li khona ho fumana phofu ea tsona ka mokhoa o bitsoang chemotaxis moo ba hlokomelang lik'hemik'hale tse hlahisoang ke ho khaola kapa ho phunyeletsa 'me li fallela ho "monko" oo ka ho toba.
Sena ha se tšoane le mekhoa ea ho itšireletsa mafung ea bobeli e hlahisang meriana e hlahisang lisele tse loketseng ho bolaea pathogen eo le hore pathogen e le mong. Ho itšireletsa mafung, ho fapana le hoo, ho bolaea ntle le ho toba, ho hlasela ntho leha e le efe e sa "nkha" hantle.
Li-neutrophils li arabela ho mafu a ka hare ho 'mele le holim'a letlalo.
Pus , e leng e 'ngoe ea likokoana-hloko tsa tšoaetso ea letlalo, haholo-holo e na le li-neutrophil tse shoeleng, libaktheria le lisele tsa letlalo.
Seo Lintho Tse Nang le Neutrophil li re Bolelletseng
Li-neutrophils li nkoa e le karolo ea teko e feletseng ea mali (CBC) . Tlhahlobo e 'ngoe, e bitsoang phapang ea WBC , e hlalosa karolo ea mofuta o mong le o mong oa lisele tse tšoeu tsa mali ka sampong ea mali, ho akarelletsa le neutrophils, lymphocytes, monocytes, basophils le eosinophils.
Ho sa le joalo, palo e feletseng ea neutrophile (ANC) e re bolella hore na lisele tse kae li maling a nang le sebaka sa "tloaelehileng" se pakeng tsa lisele tsa 1800 le 7800 ka microliter (mL).
Ntho e phahameng ea neutrophil, e tsejoang e le neutrophilia , e ka bakoa ke tšoaetso leha e le efe, ho tsieleha kapa ho ruruha ho etsang hore sesole sa 'mele se sebetse. Neutrophilia e tloaelehile ka appendicitis, ho chesa haholo, mefuta e itseng ea kankere ea mali, le boemo leha e le bofe bo bakang ho ruruha ho matla (tse kang lefu la pelo).
Ka lehlakoreng le leng, palo e fokolang, e tsejoang e le neutropenia , e ka bakoa ke sepsis , chemotherapy, kalafo ea mahlaseli, le mathata a itseng a ho iketsetsa mali. Batho ba bang, neutropenia e ka ba e sa foleng (e tsoelang pele le e tsitsitseng) ha tse ling li tla ba tsa nakoana (hangata ho arabela lefu kapa ho sebelisa lithethefatsi).
Ho Lebela Neutrophils Kankereong ea Kankere
Nakong ea phekolo ea kankere , palo e nepahetseng ea neutrophil e hlahlojoa ka mokhoa o tloaelehileng ho fumana hore na tsamaiso ea 'mele ea ho itšireletsa mafung e arabela khatello ea radiation kapa chemotherapy. Neutropenia e tloaelehile maemong ana mme e ka hlalosoa e le:
- Phofo e bonolo (ANC e ka tlaase ho 1500 lisele / mL) e nang le kotsi e fokolang ea tšoaetso.
- Neutropenia e itekanetseng (ANC pakeng tsa lisele tse 1000 le 500 / mL) e leng kotsi ea ho tšoaetsoa.
- Ho ba le leutropenia e matla (ANC e ka tlase ho lisele tse 500 / mL) e bakang kotsi e kholo ea tšoaetso.
Haeba ANC e theohela ka tlaase ho lisele tse ka bang 500 / mL, ngaka ea hau e ka 'na ea fana ka meriana e ntlafatsang maemo a neutrophil' me e ka fana ka lithibela-mafu tse thibelang tšoaetso e tebileng.
> Mohloli:
> Batho ba tsubang, L .; Hiemstra, I .; Kuijsper, T .; et al. "Neurophils kankere." Immunol Rev. 2016; 3273 (1): 312-28.