Beta Amyloid Protheine, Plaque le Alzheimer's

Protheine ea li-beta-amyloid le plaque - tsena ke mantsoe a mabeli a amanang le boko bo fetohang lefung la Alzheimer's. U batla ho tseba ho eketsehileng? Mona lintlha tse 9 ho uena:

1. Protheine ea beta-amyloid ea buildup ka boko e nkoa e le e 'ngoe ea likarolo tsa lefu la Alzheimer . (Ponahalo e 'ngoe e kholo ke likhahla tsa mahlaba-peloana .) Liprotheine tsena tsa beta-amyloid lia kopana ho etsa li-plaque tse sa khone ho qhaqha ka ntle ho li-neurons.

1. Li-proteine ​​tsa beta-li-amyloid li boetse li haha li-synapses ebile li kena-kenana le puisano ho tloha seleng e 'ngoe ho ea ho e' ngoe bokong.
2. Pele karolo ea beta-amyloid e le khōlō hoo ho ka thoeng ke lejoe , liprotheine tsena li qala ho theha oligomers . Li-oligomers li sa ntse li qhibiliha (li khona ho qhibiliha), lihlopha tse nyenyane tsa beta-amyloid.
3. Le hoja li-plaque li 'nile tsa tsejoa e le e' ngoe ea lisosa tsa Alzheimer's, bafuputsi ba sa tsoa e bitsa potso ena, ho tseba li-oligomere tse hlalositsoeng ka holimo e le mohlomong e le e 'ngoe ea litlamorao tse ka sehloohong ho thibela puisano ho tloha seleng ho isa ho sele. Lebaka le leng ka mor'a sena ke hore batho ba bang ba na le li-plaque tse hahang bokong, empa ha ba na matšoao a lefu la Alzheimer .
4. Ho phaella moo, lipatlisiso tse ling li bontšitse hore liphetoho tse nang le tsebo li bonahala eka li qala ka pele li-proteine ​​tsa beta-amyloid li tsoa likarolong tse khōloanyane tsa lejoe.
5. Saense e fumane li-proteine ​​tsa beta-amyloid lilemo tse fetang 100 tse fetileng. Ba ile ba qala ho khetholloa ke Dr. Alois Alzheimer ka 1906.

1. Beta-amyloid ke karolo ea protheine e khōloanyane e bitsoa protheine ea propylene ea amyloid .
2. Tlhaloso e thahasellisang: "Bo-rasaense ba bangata ba boetse ba nahana hore plaques ha e le hantle e ka 'na ea e-ba boiteko ba morao-rao ba boko ba ho fumana beta-amyloid e kotsi ho tloha li-neurons" (Alzheimer's Disease Education and Referral Center).
3. Phuputso e entsoeng Setsing sa mafu a UC Davis Alzheimer e fumane hore tsamaiso ea 'mele ea ho itšireletsa mafung e arabela ka tsela e tšoanang le ea sekontiri joalokaha e ile ea etsa ho libaktheria, e bakang ho ruruha bokong bo senyang li-neurons. Ho ruruha bokong ho amana le lefu la Alzheimer.

Lisebelisoa:

_{Mokhatlo oa Alzheimer's. Tlhahlobo ea lithethefatsi tsa Alzheimer Targeting Beta-Amyloid le "Hypothesis" ea "Amyloid Hypothesis." 2008.}

_{Mokhatlo oa Alzheimer's. Tse eketsehileng ka Plaque.}

_{Mokhatlo oa DANA Foundation. 'Oligomers' ea Amyloid-Beta e ka 'na ea Kopana le Tlhahlobo ea Alzheimer's Dementia. La 12 July, 2010.}

_{Setsi sa Sechaba sa Botsofali. Maloetse a Alzheimer Thuto le Boipheliso. La 22 January, 2015.}

_{Stanford Medicine. Bo-rasaense ba senola kamoo Beta-sekholo se ka sebelisang Alzheimer kateng. September 2013.}

_{Mokhatlo oa Bophelo oa UC Davis. Ho etsa hore Alzheimer le Baktheria ba qobe ho arabela ka tsela e tšoanang.}