Compazine, Thorazine, le Reglan bakeng sa Litlhaselo tsa Migraine le Nausea
Batho ba fetang halofo ba hlahisa ho soasoa le ho hlatsa nakong ea tlhaselo ea migraine. Kaha dopamine ea neurotransmitter e 'nile ea e-ba mohokahanyi ea ka sehloohong oa ho nyekeloa ke pelo nakong ea migraine, meriana e thibelang li-receptor (tse bitsoang bahanyetsi ba dopamine) li atleha ho fokotsa ho nyefoloa le ho hlatsa. Ho thahasellisang ke hore li-antiemetics tsena li boetse li fokotsa bohloko ba migraine, kahoo li atisa ho sebelisoa e le phekolo feela ea ho phekola migraine e matla haholo.
Compazine ka Treaty ea Migraine
Li-antipsychotics tse kang Compazine (prochlorperazine) li atisa ho sebelisoa ho tšoara migraine e matla le ho nyeheloa ha pelo.
Ho phaella tabeng ea ho phekola leqeba le ho hlatsa haholo, Compazine e boetse e sebelisoa ho phekola schizophrenia le kalafo ea nakoana ea khatello ea kelello e se nang kelello. Compazine e fumaneha e le matlapa, li-capsules tse lokolitsoeng, tse nang le metsi a molomo, li-suppositories le li-vials - tse fanoang ka intravenously (ka har'a methapo) kapa ka hare ho eona (ka har'a mesifa). Ka lebaka la bothata ba meriana ea molomo e nang le lithethefatsi le ho hlatsa tse amanang le migraine, Compazine e fanoa ka intravenously kapa intramuscularly bakeng sa phomolo ea matšoao - hangata ka kamoreng ea tšohanyetso, setsi sa tlhokomelo e potlakileng, kapa kliniki.
Litla-morao tse ling tsa Compazine li kenyeletsa ho otsela, ho ba le botenya, ho ponoa habonolo, ho itšoara ha letlalo, khatello e tlaase ea mali le amenorrhea. Liphello tsa Extrapyramidal li ka boela tsa hlaha joaloka li-spasms tsa mesifa, ho se phomole, parkinsonism , kapa dyskinesia e hlahelletseng.
Tsela e sa tloaelehang empa e ka 'na ea e-ba kotsing ea ho bolaea Compazine (le likokoana-hloko tse ling) ke Neuroleptic Malignant syndrome, e bakang matšoao a fapa-fapaneng ho akarelletsa feberu, ho thatafala ha mesifa le pherekano.
Thorazine ka Treaty ea Migraine
Thorazine (chlorpromazine) ke e 'ngoe ea li-antipsychotic e sebelisetsoang ho phekola migraine e matla le ho ts'oaea le ho hlatsa ho amanang.
Joaloka Compazine, hangata e fanoa ka intravenously kapa intramuscularly bakeng sa thuso ea migraine le ea ho nyeheloa ke pelo. Ho ea ka phuputso ea 2013 ho Journal of Emergency Medicine , Thorazine e ile ea ntlafatsa bohloko ba hlooho, ho nyekeloa ke pelo, le kutloisiso ea khanya le molumo ho batho ba nang le migraine ha bapisoa le batho ba ntseng ba nka placebo (saline infusion). Empa thutong ena, batho ba bangata ba ile ba oela bosiu le ho ba le botsoa ha ba ema ha ba nka Thorazine, ha ba bapisoa le batho ba amohetseng sebaka sa placebo.
Reglan in Treatment ea Migraine
Reglan (metoclopramide) e boetse e thibela li-receptor tsa dopamine. Empa ho fapana le mefuta e meng ea li-antipsychotics, e sebelisetsoa ho eketsa motility oa mokokotlo ho batho ba nang le mathata a ho ntša mala a bona, joaloka batho ba nang le lefu la tsoekere. Ho tšoana le Compazine, Reglan e boetse e sebelisetsoa ho phekola ho nyefoloa ho amanang le migraine le ho hlatsa, haholo-holo kamoreng ea tšohanyetso kapa tlhokomelo e potlakileng, 'me e sebetsa hantle. Ha e le hantle, phuputso e 'ngoe ea ho hlahlobisisa ea Cochrane ea 2013 e fumane hore ho kopanya Reglan le aspirin ho ntlafalitse ts'oaetso le ho hlatsa tse nang le litla-morao tse seng kae ha li bapisoa le triptan Imitrex (sumatriptan).
Le hoja Reglan a atisa ho ba le litla-morao tse seng kae ho feta li-antiemetics tse ling, tse tloaelehileng li kenyelletsa:
- ho se phomole
- ho khathala
- botsoa
- hlooho
- pherekano
- mathata a robetseng
Joaloka Compazine leha ho le joalo, litla-morao tse tebileng joaloka matšoao a extrapyramidal le Neuroleptic Malignant Syndrome e ka hlaha (e sa tloaelehang). Reglan e ka eketsa kotsi ea motho bakeng sa ho tepella maikutlong le maikutlo a ho ipolaea.
Ntho e ka tlaase
Bakeng sa ho ts'oaea le ho hlatsa ho amanang le migraine, meriana e thibelang li-receptor tse bokoeng (bo-dopamine bahanyetsi) li atisa ho sebelisoa, haholo-holo Compazine, Thorazine, kapa Reglan. Le hoja meriana ena e sebetsa hantle, e na le kotsi e itseng. Etsa bonnete ba hore o tsebisa ngaka ho u tšoara ka mathata ohle a bophelo bo botle le meriana, ho akarelletsa le livithamini, li-supplement, le litlhare tse fetang tse ling.
Lisebelisoa:
Bigal ME, Bordini CA & Speciali JG. Intravenous chlorpromazine lefapheng la tšohanyetso lefapha la migraine: teko e laoloang ka nako eohle. J Emerg Med . 2002 Aug; 23 (2): 141-8.
Flake ZA, Linn BS & Hornecker JR. Khetho e sebetsang ea antiemetics sebakeng sa boemeli. Am Phys Physician 2015 Mar 1; 91 (5): 29306.
Láinez M JA, García-Casado A & Gascón. Tlhokomelo e nepahetseng ea ho nyekeloa ke pelo le ho hlatsa ka migraine: ho ntlafatsa liphello tsa mokuli. Measine ea Mahlomola e Amanang le Mamello . 2013; 4: 61-73.
US Administration of Drug and Drug Administration. Tataiso ea Meriana: Compazine. E fihlile ka la 4 February, 2016.
US Administration of Drug and Drug Administration. Tataiso ea Meriana: Reglan (ente ea metoclopramide). E fihliloe ka la 5 February, 2016.
LITLHAHISO: Boitsebiso bo sethaleng sena ke merero ea thuto feela. Ha ea lokela ho sebelisoa e le sebaka sa tlhokomelo ea botho ke ngaka e nang le tumello. Ke kopa o bone ngaka ea hau bakeng sa ho hlahlojoa le ho phekoloa leha e le efe mabapi le matšoao kapa boemo ba bongaka .