Puisano le Dr. Edward M. Wolin, MD
Ho shoa ha Steve Jobs ho tswa ho mofuta o sa tloaelehang oa kankere ea pancreatic e bitsoang kankere ea pancreatic neuroendocrine e hlahisitse thahasello kankere ea pancreatic. Puisanong ena, Dr. Edward Wolin, setsebi sa kankere ea boloetse ba methapo ea mafu a kereke ea Cedars Sinai Medical Center, o tšohla kankere ea pancreatic neuroendocrine le hore na bakuli ba loantša lefu lena joang. Dr. Wolin ke motsamaisi-'moho le lenaneo la Carcinoid le Neuroendocrine Tumorong ea Cedars-Sinai Medical Centre 'me o na le mekhoa e kholo ka ho fetisisa ea sechaba e tsebahalang ka kankere ea pancreatic neuroendocrine.
Ha aa ka a tšoara Steve Jobs.
Na u ka hlalosa hore na kankere ea pancreatic neuroendocrine ke eng?
Kankere ea kankere ea kankere ea kankere ea kankere e ntseng e hōla butle-butle e qalang liseleng tsa endocrine (lisele tse hlahisang lihomone tsa hormone) tsa li-pancreas, tse tsejoang hape e le lisele tsa lisele. Le hoja lihlahala tsena li ka hlahisa lihomone tse ngata tsa pancreatic, tse ngata ha li hlahise lihomone. Hangata li hasana sebakeng sa mpa le sebete nakong ea ho hlahlojoa. Leha ho le joalo, palo ea ho pholoha hangata e phahame ho feta mofuta o tloaelehileng oa kankere ea pancreatic (adenocarcinoma) , esita le ha metastases e le teng.
E fumanoa joang? Na ho na le matšoao?
Ha lik'hemik'hale tsena li hlahisa lihomone, matšoao a mathoasong a ka ba matla 'me a lebisa ho hlahlojoa kapele. Ka mohlala, kokoana-hloko e hlahisang insulin e baka matšoao a tsoekere e tlaase haholo ea mali , kapa hlahala e hlahisang gastrin e bakela liso tse matla tsa mala le tsa duodenal, tse lebisang ho hlahlojoa ke CT scan, MRI scan, kapa endoscopic ultrasound ea pancreas.
Haeba tlhahiso ea hormone e sa bake lipontšo tsa lingaka, mafupa a tla atisa ho hōla ka boholo le ho hasana sebeteng le libakeng tse ling ka nako ea ho fumanoa ho CT kapa MRI. Maemong ana, matšoao a pele e ka 'na ea e-ba bohloko ba mpeng, lefu la khama, ho lahleheloa ke boima ba' mele, malaise, ho senya mpa, ho hlatsa, ho phatloha ha letlalo, bofokoli le letšollo.
Ke mang ea kotsing? Na ka karolelano, motho ea phetseng hantle o tla ameha ka kankere ea pancreatic neuroendocrine?
Tsena ke lipolao tse sa tloaelehang haholo, tse nang le liketsahalo tse tharo tsa Maamerika a limilione, tse etsang karolo ea 3 lekholong ea kankere ea pancreatic. Ka hona, ka karolelano, motho ea phelang hantle ha aa lokela ho ameha ka ho hlahisa kankere ea pancreatic neuroendocrine. Ntho e ikhethang ke malapeng a mang moo kankere ea pancreatic neuroendocrine e tloaelehile, hangata e phela le lihlapa tsa parathyroid le pituitary . Khetho ena ea lelapa e tsejoa e le multiple multiple neurolasia neoplasia type 1 (MEN-1).
Na re tseba hore na ke eng e e bakang?
Rea tseba hore phetoho - setho sa botona se hlahisang MEN-1, 'me rea tseba hore liphetoho tse ling tse sa tloaelehang tsa liphatsa tsa lefutso li atile haholo kankere ea pancreatic neuroendocrine, empa hangata sesosa ha se tsejoe.
Na ho na le litsela tsa ho fokotsa kotsi kapa ho thibela kankere ea pancreatic neuroendocrine?
Ha ho mokhoa o tsejoang oa ho fokotsa kotsi kapa ho thibela kankere ea pancreatic neuroendocrine.
Ke lits'ebeletso life tse fumanehang?
Ka lebaka la ho se fumaneha ha lihlahala tsena ho batho ba bangata, 'me mofuta o khethehileng oa tlhokomelo o hlokahalang, bakuli ba khothalletsoa haholo hore ba batle lipuisano ho tsoa setsing se khethehileng sa kankere ea li-neuroendocrine. Libakeng tse joalo, ho na le tšebelisano e haufi-ufi le bongaka ba bongaka , bongaka bo sebetsanang le lefu la ho phekola, lefu la ho kula, ho buuoa ka bongata, ho buuoa ka bongaka, ho sebelisoa ha radiology, ho sebelisoa ha radiology le meriana ea nyutlelie ho ntlafatsa tlhokomelo ea motho ka mong.
Litlhare li kenyelletsa resection ea li-tumor tse ka sehloohong le metastases, ho tlosoa ha metastases ka li-microwaves, ho phekola lihlahala le mahlaseli a intrahepatic (radioembolization) le intrahepatic chemotherapy (chemoembolization), ho thibela ho hōla ha hlahala le lihlaseluoa tse hlalositsoeng (somatostatin analogs, m-TOR inhibitors, tyrosine kinase inhibitors , phekolo ea radionuclide e tsejoang e le PRRT, phekolo ea meriana, le lithethefatsi tse khahlanong le angiogenic), le tšebeliso ea kokoana-hloko ea molomo e tlaase.
Ho ithuta ho eketsehileng ka Dr. Edward Wolin le tloaelo ea hae setsing sa Bongaka sa Makedare Sinai, ka kopo, etela sebaka sa Cedars Sinai.