Lisosa tse hlileng li bakoang ke kankere ea pancreatic ha li tiisehe, empa lisosa tse kotsing li ka kenyelletsa lilemo, thobalano, morabe, liphatsa tsa lefutso tse kang histori ea lelapa la lefu lena, le mathata a bophelo a kang ho tsuba, tšebeliso ea joala, botenya, esita le boloetse ba bolo.
Ha matšoao a kankere ea pancreatic e ka 'na ea se ke ea hlaha ho fihlela e tsoetse pele, ke habohlokoa hore u hlokomele hore na lintlha tsena li ka ba le tšusumetso ea kotsi ea hau joang e le hore u ka etsa sohle seo u ka se khonang ho se fokotsa le ho buisana le ngaka ea hau.
Mathata a Tloaelehileng a Likotsi
Ho ba le kotsing ea kankere ea pancreatic ha ho bolele hore u tla hlaolela lefu lena. Hangata lintho tsena ha li "bake" lefu lena, empa li tloaelehile ho batho ba li hlahisang. Ka ho tšoanang, batho ba bangata ba hlahisang kankere ea pancreatic ha ba na likotsi tse totobetseng. Seo se boletse hore, mabaka a mangata a kotsi, u na le menyetla e kholo ea ho tobana le kankere ea pancreatic ka nako e itseng bophelong ba hau.
Lintho tse kotsi li ka kenyelletsa:
Lilemo
Kotsi ea kankere ea pancreatic e eketseha ka botsofali, le hoja ho ka khoneha hore motho a fumanoe a sa le monyenyane. Nakong ea hona joale, hoo e ka bang karolo ea 90 lekholong ea batho ba lilemo li ka holimo ho 55 nakong ea ho hlahlojoa, ka karolelano ea lilemo ha ba fumanoa ba le lilemo li 71.
Race
Kankere ea pancreatic e tloaelehile ho batho ba batšo ho feta ba makhooa, Maasia, kapa Hispanics, empa hape, e ka ba teng ho mang kapa mang. Batho ba Ashkenazi Jewish heritage ba na le kotsing e eketsehileng, mohlomong ka lebaka la tekanyo e phahameng ea liphetoho tsa lefutso tsa BRCA2.
Thobalano
Kankere ea Pancreatic e ne e tloaelehile haholo ho banna ho feta basali, empa lekhalo le koala. Hona joale lefu lena le batla le tloaelehile haholo ho banna.
Lefu la tsoekere
Tlhahlobo ea lefu la tsoekere ea nako e telele ke kotsi ea kankere ea pancreatic. Lefu la tsoekere le ka boela la hlaha kapele pele ho fumanoa, hangata ho batho ba se nang kotsi ea lefu la tsoekere.
Kamano ena pakeng tsa ts'oaetso ea lefu la tsoekere e sa lebelloang ho batho ba fetang lilemo tse 45 le kankere ea pancreatic e ne e le ea bohlokoa ka ho fetisisa thutong ea 2018 eo lingaka tse ling hona joale li khothalletsang ho hlahloba haeba e etsahala.
Maloetse a Gum le Tahlehelo ea Lino
Boloetse ba Gum, bo bitsoang gingivitis boemong ba pele le nakoontitisitis boemong bo tsoetseng pele, e ile ea boleloa ka lekhetlo la pele e le tšoaetso ea kankere ea pancreatic ka 2007. Tlhahlobo ea 2017 ea lithuto tse entsoeng ho fihlela joale e fumane hore batho ba ka etsang karolo ea 75 lekholong kankere ea pancreatic haeba ba ne ba e-na le periodontitis le karolo ea 54 lekholong ho ka etsahala haeba ba ne ba lahlile meno a bona (edentulism). Lebaka leo ha le tsejoe ka tieo, empa ho nahanoa hore libaktheria tse ling tse phelang molomong li etsa mochine o etsang hore liphetoho tsa mofuta o mong oa liphatsa tsa lefutso ( p53 tsa phetoho ea lefutso ) li ka lebisa kankere ea pancreatic.
Chronic Pancreatitis
Tlaleho ea ho tšoaroa ke lefu le sa foleng e ka eketsa kotsi ea kankere ea pancreatic, haholo-holo ho batho ba tsubang. Hangata pancreatitis e hloekileng e qala bongoaneng 'me e amahanngoa le kotsi e phahameng haholo ea lefu lena.
Memo e meng ea bongaka
Bacteria Helicobacter pylori ( H. pylori ) ke sesosa se tummeng sa kankere ea mala, hammoho le boloetse ba seso sa sesapo.
Ho nahanoa hore e ka eketsa kotsi ea kankere ea pancreatic. Ho na le bopaki bo bong bo bontšang hore tšoaetso ea lefu la sebete la mofuta oa B , li-gallstones , ho buuoa ka bongata, le sebete sa sebete se ka amahanngoa le kotsi e kholo ea lefu lena.
Histori ea Botho ea Kankere
Batho ba nang le histori ea botho ea mefuta e sa tšoaneng ea kankere ba na le monyetla oa ho hlahisa kankere ea pancreatic. Bafuputsi ha ba tsebe hantle hore na sena se amahanngoa le likarolo tse ling tsa kankere ka tsela e itseng, kapa haeba likahanyo li bakoa ke likotsi tse tloaelehileng tsa lik'hemik'hale tsena (tse kang ho tsuba).
Mofuta oa Mali
Batho ba nang le mefuta ea mali A, B, le AB ba bonahala ba e-na le kotsing e kholo ea kankere ea pancreatic ho feta ba nang le mofuta oa mali O.
Lik'hemik'hale
Ho nahanoa hore batho ba sebetsang ka thata mosebetsing ba tlatsetsa karolo ea 2 lekholong ho karolo ea 3 lekholong ea kankere ea pancreatic, e nang le lik'hemik'hale tse amehang ka ho fetisisa ke li-hydrocarbone tsa hydrocarbon le polycyclic e nkhang hamonate ea hydrocarbon (PAHs). Basebetsi bao kotsi e ntseng e eketseha e bileng teng ho kenyeletsa ho hloekisa e omisitsoeng le basebetsi ba laboratori ba basali.
Liphatsa tsa lefutso
Hoo e ka bang karolo ea 10 lekholong ea kankere ea pancreatic e nkoa e le lefa le e amanang le histori ea malapa ea lefu lena kapa lefu la itseng la liphatsa tsa lefutso.
Histori ea Lelapa
Batho ba nang le tlaleho ea malapa ea kankere ea pancreatic ba na le monyetla oa hore ba hlaolele lefu lena. Hape ho na le ho hong ho thoeng ke kankere ea malapa ea pancreatic. Motho o nkoa a e-na le sena haeba beng ka eena kapa ba fetang lekholo la pele (motsoali, ngoan'eno, kapa ngoana) kapa litho tse ling tse tharo kapa tse fetang tse ling tsa malapa (bo-nyalane, bo-malome, bo-motsoala) ba na le lefu lena.
Li-Syndromes tsa Genese
Li-syndromes tsa mafu tse amanang le kankere ea pancreatic hangata li amahanngoa le liphetoho tse itseng tsa lefutso. Boholo ba liphetoho tsena tsa lefutso, tse kang liphetoho tsa lefutso la BRCA2 , li na le liphatsa tsa lefutso tse tsejoang e le likokoana-hloko tse bakang liphatsa tsa lefutso . Melao ea liphatsa tsa lefutso bakeng sa liprotheine tse loantšang DNA e senyehileng le ho fokotsa ho hōla ha lisele. Matšoao a amanang le kotsi e kholo a kenyeletsa:
- Sefuba sa Hereditary le lefu la kankere ea mahe a bomalimabe
- K'homphieutha e nang le seriti
- Lefu la Peutz-Jeghers
- Lynch syndrome (lefu la kankere le se nang mokokotlo oa li-nonpolyposis, HNPCC)
- Li-Fraumeni syndrome
- ho tloha Hippel Lindau syndrome
- Familial adenomatous polyposis
- Matšoao a tloaelehileng a multipley mole mole melanoma (FAMMM)
- Ataxia telangiectasia
- Bongata ba endocrine neoplasia mofuta oa 1 (MEN1) syndrome (li-tumor tsa neuroendocrine)
- Neurofibromatosis mofuta oa 1 (li-tumor neuroendocrine)
Lintho tsa Likotsi Tsa Bophelo
Lintho tse phelang li ka phetha karolo ea bohlokoa ho nts'etsong ea kankere ea pancreatic 'me e kenyeletsa:
Ho tsuba
Ho tsuba ho eketsa kotsi ea kankere ea pancreatic tse peli ho isa ho tse tharo 'me ho nahanoa hore e ikarabella bakeng sa hoo e ka bang karolo ea boraro ea kankere. Ho fapana le kankere ea matšoafo, eo kotsi e ntseng e tsoela pele ka nako e telele ka mor'a hore motho a tlohele ('me a se ke a khutlela ho tloaelehileng), kotsi ea kankere ea pancreatic e khutlela ho tloaelehileng pele ho lilemo tse hlano ho ea ho tse 10 tsa ho tlohela.
Joala
Nako e telele, ho noa joala haholo (lino tse tharo kapa ho feta letsatsi le letsatsi) ho amahanngoa le kotsi e eketsehileng ea kankere ea pancreatic. Kotsi e ka 'na ea amahanngoa le kotsi e eketsehileng ea ho ba le tšoaetso ea kelello ho batho ba noang joala bo bongata haholo (haholo ha ba kopane le ho tsuba) ho e-na le ho noa joala. Ho sebelisa joala hampe ha ho bonahale eka ho eketsa kotsi.
Botenya
Ho ba boima bo feteletseng kapa ho ba mafura ho phahamisa kotsi ea kankere ea pancreatic hoo e ka bang karolo ea 20 lekholong. Ho lumeloa hore hoo e batlang e le e 'ngoe ea lik'hemik'hale tse tšeletseng tsa kankere e amanang le botenya.
Lijo
Ho na le bopaki bo bong ba hore lijo tse nang le mafura a mangata, hammoho le lijo tse ngata tse khubelu kapa tse entsoeng, li ka 'na tsa ama kotsing e eketsehileng ea kankere ea pancreatic, haholo-holo ha lijo li pheha licheso. Ka lehlakoreng le leng, lijo tse phahameng tse nang le asiti ea folic, tse kang meroho e tala, li ka ba le phello e sireletsang. Phuputso ea 2017 ea lipatlisiso mabapi le lijo le kankere ea pancreatic e fumane hore lijo tsa Bophirimela li amana le monyetla o moholo oa 24 lekholong oa ho hlaolela lefu lena. Kofi e ka 'na ea eketsa kotsi hape.
Tsela ea ho phela ka nako e telele
Ho phela ka nako e telele, joalo ka ho sebetsa mosebetsing oa desk, ho ka eketsa kotsi, empa ha ho netefatsoe ka nako ena.
> Mehloli:
> Mokhatlo oa American oa Clinic Oncology. Kankere.Net. Kankere ea Pancreatic: Lintho Tsa Kotsi. E fetotsoe 12/16. https://www.cancer.net/cancer-types/pancreatic-cancer/risk-factors
> Khadka, R., Tian, W., Xin, H., le R. Koirala. Sesosa sa Kotsi, Tlhahlobo ea Pele le ho Pholoha ka ho Fetisisa ka Phello ea Kopano pakeng tsa Kankere ea Pancreatic le lefu la tsoekere Mellitus: Liphetoho le Tsoelo-pele, Tlhahlobo. International Journal of Surgery . 2018 Mar. 10. (Epub pele ea khatiso).
> Lu, P., Shu, L., Shen, S. le al. Mekhoa ea Lijo le Kotsi ea Kankere ea Pancreatic: Meta-Analysis. Metsoako . 2017. 9 (1) .pii: E38.
> Maisonneuve, P., Amar, S., le A. Lowenfels. Maloetse a Periodontal, Edentulism, le Kankere ea Pancreatic: A Meta-Analysis. Annals of Oncology . 2017. 28 (5): 985-995.
> Mokhatlo oa Kankere ea Sechaba. Pancreatic Cancer Treatment (PDQ) -Patient Version. E ntlafalitsoe ka 03/22/18. https://www.cancer.gov/types/pancreatic/patient/pancreatic-treatment-pdq