Chamomile li-supplement ha li e-s'o hlahlojoe polokeho 'me li hopola hore polokeho ea litlatsetso ho basali ba nang le bakhachane, bo-'mè ba tlhokomelo, bana, le ba nang le maemo a bophelo kapa ba noang meriana ha e e-s'o thehoe. Etsa bonnete ba hore u ithute ka ho sebelisa lisebelisoa tse sireletsehileng , 'me haeba u nahana ka tšebeliso ea chamomile, buisana le ngaka pele.
Ka kopo hlokomela hore lena ke lenane feela le fokolang (ka kōpo ikopanye le ngaka ea hao bakeng sa lenane le feletseng). Tse ling tsa likamano tse ka khonehang tsa lithethefatsi li ka kenyelletsa:
Aspirine
Aspirin e ka 'na ea sebelisana le chamomile, e nang le metsoako ea anticoagulant e bitsoang coumarins le ho eketsa kotsi ea ho tsoa mali.
Platelet Inhibitors
mohlala Ticlopidine (Ticlid), Clopidogrel (Plavix)
Platelet inhibitors e sebelisetsoa ho fokotsa kotsi ea lefu la pelo kapa la stroke le bakeng sa bakuli ba kileng ba e-ba le limela tse nang le limela tsa 'mele. Chamomile e na le metsoako ea anticoagulant e bitsoang coumarins. Ha li kopantsoe, li ka eketsa kotsi ea ho tsoa mali.
Anticoagulants
mohlala, Warfarin (Coumadin)
Warfarin e tsoa ho coumarin, setsi se nang le li-anticoagulant le tsona li fumanoe ka chamomile. Tee ea Chamomile e fumanoe e baka tšollo ea mali ka hare ha e kopantsoe le coumarin.
Tricyclic Ho tepella maikutlo
mohlala, Amitriptyline (Elavil, Endep), Clomipramine (Anafranil), Imipramine (Tofranil)
Tricyclic e thibelang ho imeloa kelellong e sebelisoa ka metsoli 'meleng ka CYP1A2 ea enzyme. Ho fumanoe hore Chamomile e thibela CYP1A2 'me e ka' na ea theha haholo ho eketsa likarolo tsa mali tsa tricyclic ho loantšana le khatello ea kelello, ho eketsa kotsi ea chefo.
Clozapine
Clozapine (Clozaril, Leponex, Fazacio) e na le metaboli 'meleng ka motsoako oa CYP1A2.
Ho fumanoe hore Chamomile e thibela CYP1A2 mme e ka 'na ea etsa hore ho be le likarolo tsa mali tsa Clozapine, ho eketsa kotsi ea chefo.
Propranolol
Propranolol (Inderal) ke beta-blocker e sebelisetsoang ho tšoara khatello ea mali e phahameng. E na le methapoli ea 'meleng ka motsoako oa CYP1A2. Ho fumanoe hore Chamomile e thibela CYP1A2 'me e ka' na ea utloahala ho eketsa lipeo tsa mali tsa Propranolol, ho eketsa kotsi ea chefo.
Theophylline
Theophylline (mohlala Theo-24, Theolair, Bronkodyl, Slo-bid, Slo-Phyllin, Theobid, Theo-Dur, TheolairSR, Uni-Dur) ke bronchodilator e sebelisitsoeng ho thusa batho ba nang le maemo a matšoafo ho hema habonolo. E na le methapoli ea 'meleng ka motsoako oa CYP1A2. Ho fumanoe hore Chamomile e thibela CYP1A2 'me e ka' na ea itšetleha haholo ka ho eketsa likarolo tsa mali tsa Theophylline, ho eketsa kotsi ea chefo.
Tacrine
Tacrine (Cognex) e thusa ho tšoara matšoao a amanang le lefu la Alzheimer kapa 'dementia'. E na le methapoli ea 'meleng ka motsoako oa CYP1A2. Ho fumanoe hore Chamomile e thibela CYP1A2 'me e ka' na ea etsa hore ho be le likarolo tsa mali tsa Tacrine, ho eketsa kotsi ea chefo.
> Mehloli:
> Cupp MJ le Tracy TS. "Cytochrome P450: > e ncha > botumo ba nomenclature le litlhoko tsa bongaka." Ngaka ea Lelapa la Amerika. 57.1 (1998): 107-16.
> Ganzera M et al. "Litholoana tse thibelang matla a oli ea bohlokoa ea chamomile (Matricaria recutita L.) le likarolo tsa eona tse kholo li-enzyme tsa cytochrome P450." Life Sciences. 78.8 (2006): 856-61.
> Maliakal PP le Wanwimolruk S. "Phello ea likhahla tsa litlama moriana o tsitsitseng oa metsolizing likokoanyana." Journal ea Pharmacy le Pharmacology. 53.10 (2001): 1323-9.
Taba e nepahetseng: Boitsebiso bo boletsoeng setšeng sena bo reretsoe merero ea thuto feela 'me ha bo nkele sebaka keletso, ho hlahlojoa kapa kalafo ke ngaka e nang le tumello. Ha e reretsoe ho koahela mekhoa eohle ea tlhokomelo, likamano tsa lithethefatsi, maemo kapa liphello tse bohloko. U lokela ho batla thuso ea meriana hang-hang bakeng sa bophelo bo botle le ho buisana le ngaka pele u sebelisa mefuta e meng ea phekolo kapa u etse phetoho tsamaisong ea hau.