Ramatiki ea Psoriatic ke lefu la ramatiki le sa foleng. E ka ba tsoelo-pele 'me e lebisa tšenyo e sa khaotseng le ho holofala. Ka kakaretso, lefu la psoriatic le nkoa le sa tloaeleha, empa le tloaelehile har'a batho ba nang le psoriasis, e amang pakeng tsa 6-10% ea bakuli ba psoriasis. E atile le ho feta har'a ba nang le psoriasis e matla, e amang 20-40% ea sehlopha seo sa bakuli.
Ke habohlokoa ho hlokomela lisosa tsa kotsi tse amanang le ramatiki ea psoriatic. Ntho e kotsi ke tšobotsi kapa ntho e etsang hore motho a hlaheloe ke boloetse bo itseng kapa boemo bo itseng. Lintho tse kotsi li hlalosoa e le tse fetoloang kapa tse sa fetoheng. Bothata bo fetotsoeng bo ka beha monyetla oa ho thibela ramatiki ea psoriatic kapa ho laola tšenyo eo e ka e bakang.
Ho khetholla likotsi tse bakoang ke ramatiki ea psoriatic e ne e le nako e khutšoanyane. Ho ne ho e-na le liphuputso tse fokolang tsa lefu lena tse ileng tsa hlahloba likotsi tsa lefu la psoriatic ho fihlela ho pholletsa le selemo sa 2000. Hape ho bile le lipatlisiso tse fokolang tse ileng tsa hlahloba lisosa tsa kotsing ea ho hlahisa ramatiki ea psoriatic har'a batho ba nang le psoriasis. Bafuputsi ba 'nile ba etsa qeto ea hore ho ka' na ha etsahala hore lefu la masapo a psoriatic le hlahe ka lebaka la liphatsa tsa lefutso, immunologic le maemo a kotsi a tikoloho.
Liphatsa tsa lefutso
Hoo e ka bang 40% ea bakuli ba nang le psoriasis kapa ramatiki ea psoriatic ba na le litho tsa lelapa tse nang le psoriasis kapa psoriatic arthritis. Liphuputso li bontšitse hore bakuli ba nang le histori ea malapa ea lefu la psoriatic ba bile le menyetla e fetang 27-48 ea ho hlaolela lefu lena ho feta ba se nang pale ea lelapa.
Matšoao a mafu a kelello a nkoa e le "a bohlokoa haholo" ho feta maloetse a mang a mangata .
Bana ba batsoali ba nang le psoriasis ba na le menyetla e mengata ea ho hlahisa psoriasis le ho ba le kotsi e kholo ea ho hlahisa ramatiki ea psoriatic ha e bapisoa le bana ba batsoali ba se nang psoriasis. Haeba mafahla a tšoanang a na le ramatiki ea psoriatic, lehlakoreng le leng le tšoanang le lona le na le monyetla o moholo oa ho ba le lefu lena kapa ho le hlahisa qetellong. Liphatsa tsa lefutso tse ngata tse amahanngoa le ramatiki ea psoriatic li boetse li amahanngoa le ho hoheloa ke psoriasis. Empa, hase liphatsa tsohle tsa lefutso tse amanang le maloetse ka bobeli.
Immunologic
Mefuta e fapaneng ea tsamaiso ea immune e tlatsetsa ho eketsa kotsi ea lefu la masapo a psoriatic. Lisele tse T tse entsoeng li teng lithong tsa letlalo le manonyeletso. Ho boetse ho nahanoa hore li-cytokine , tse kang TNF-alpha, li phetha karolo ea ho ruruha ha lefuba le ho ruruha ha letlalo ho amanang le ramatiki ea psoriatic.
Tikoloho
Ho na le mabaka a tikoloho a bonahalang a amana le kotsi ea ho hlahisa ramatiki ea psoriatic. Ho pepesa ho itseng ho tšoaetsanoang ho nkoa e ka ba kotsi, haholo-holo mafu a streptococcal. The link ha e e-s'o pakoe kapa tiisetso leha ho le joalo.
Matšoao a mafu a kelello a boetse a tloaelehile bathong ba nang le tšoaetso ea kokoana-hloko ea HIV (immunodeficiency virus) ho bapisoa le batho ba bangata.
The phenomenon ea Koebner, e hlahang ka 52% ea batho ba nang le psoriasis ho ea ka Kelley's Textbook of Rheumatology, e nkoa e le mohloli o mong oa tikoloho. Taba ea pele e hlalositsoeng ke Dr. Heinrich Koebner (dermatologist ea hlomphehang haholo ho tloha lekholong la bo19 la lilemo) ka 1876, liso tsa psoriatic mofuta oa letlalo la pele le sa ts'oosoeng le latelang lefu la letlalo. Se etsa hore ketsahalo ea Koebner e ntse e sa hlaka empa li-cytokines, liprotheine tsa khatello ea kelello, limolek'hule tsa ho khomarela le li-autoantigens li ka ameha.
Lisebelisoa:
Ho Khetholla Lintho Tsa Kotsi bakeng sa Ramatiki ea Psoriatic: Sensei Monyetla o Fumana Tlhoko ea Kliniki. Ogdie le Gelfand. JAMA Dermatology. July 2010.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917977/
Tlhaloso ea mokuli: Ramatiki ea Psoriatic (Ka Ntle ho Lintho Tsa motheo) Gladman le Ritchlin. E maemong.
http://www.uptodate.com/contents/psoriatic-arthritis-beyond-the-basics
Psoriatic Arthritis. M. Elaine Husni. Cleveland Clinic. August 2010.
http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/rheumatology/psoriatic-arthritis/
The Koebner Phenomenon. Lipliniki tsa Dermatology. Sagi L. le Trau H. March-April 2011.
http://www.ncbi.nlm.nih.gov/pubmed/21396563
Kelley's Textbook ea Rheumatology. Khatiso ea borobong. Elsevier. Khaolo ea 77. Psoriatic Arthritis. Oliver Fitzgerald.