Meriana e nang le lithethefatsi e fokotsa bohloko ba pele bo bakoang ke lefu la masapo a osteoarthritis
Synvisc (hylan GF 20) ke mokelikeli oa viscous o tsoang nthong e tsejoang e le hyaluronan (sodium hyaluronate). Hyaluronan e hlahisitsoe ka tlhaho 'meleng ho thusa li-joints. Sebopeho se fumanoang Synvisc se entsoe ka li-gelatinous dintho tse fumanoang likokotheng tsa khōhō.
Synvisc e sebelisoa ka mofuta o mong oa phekolo e tsejoang e le viscosupplementation eo motsoako o kenngoang libakeng tse kopane ho thusa ho eketsa lebiso.
Tlhahlobo ea Lithethefatsi
Liente tsa synvisc li amoheloa bakeng sa phekolo ea lefu la osteoarthritis ea lengole ho batho ba hlōlehileng ho arabela kalafo e ikemetseng, ho akarelletsa le litlamo tsa li-analgesics le tse se nang lithethefatsi.
Synvisc e fanoa ka ente ea limilione tse peli ka ho toba ka lengole. Ha e e-s'o amohelehe bakeng sa monoana o mong ntle le lengole. Hangata synvisc e fanoa e le letoto la liente tse tharo tse fanoang libeke tse ling kaofela. Ho finyella sephetho se setle, metsoako ea synovial ka mahlakoreng a lengole hangata e tlosoa pele ho ente ea pele.
Ho na le sehlahisoa se seng sa Synvisc, se tsejoang e le Synvisc-One, se tsamaisoang e le palo e le 'ngoe, e etsang limilione tse tšeletseng.
Synvisc e ile ea amoheloa hore e sebelisoe ke Tsamaiso ea Lijo le Meriana ea US ka la 8 August, 1997. Synvisc-One e amohetse tumello ea eona ea FDA ka la 26 February, 2009. Litla-morao tse tloaelehileng tse amanang le Synvisc li kenyelletsa:
- Bohloko, ho ruruha, kapa boima ho lengole ka lengole
- Kotsi e kopaneng ("metsi ka mangole")
- Mahlaba a metsoako e kopaneng
- Rash kapa hives
- Feberu
- Nausea
- Hlooho ea hlooho
- Sehlōhō
- Likhalase tsa mesifa
- Mokhathala
Boholo ba matšoao ana bo bonolo ho isa tekanyong 'me bo tla rarolla bo le bong ntle le phekolo. Haeba matšoao a mang a ntse a tsoela pele kapa a mpefala, letsetsa ngaka hang-hang hobane sena e ka 'na ea e-ba letšoao la tšoaetso kapa mathata.
Katleho ea Synvisc ka ho Fokotsa Knee Surgery
Tlhahlobo ea bongaka e ile ea etsoa ho hlahloba katleho ea Synvisc ho batho ba nang le lefuba la masapo a mabeli a maoto a mabeli kapa a mabeli. Barupeluoa ba kenyelletsa basali ba 56 le banna ba 52 ba nang le lilemo tse 62. E mong le e mong o ne a hlōlehile ho fumana liphallelo ka lithethefatsi tse seng khahlanong le ho ruruha (NSAIDs) kapa li- shooting tsa cortisone .
Nakong ea nyeoe, mohoeletsi e mong le e mong o ile a amohela liente tse tharo tsa Synvisc ka beke e le 'ngoe. Litekanyetso li ile tsa etsoa ka lekhetlo le le leng, la boraro, la tse tšeletseng, la 12, la 15 le la 18. Thuto e ne e reretsoe ho hlahloba hore na barupeluoa ba ithutang bohloko bo bokae 'me ba hlokomele kamoo phekolo e sebetsang kateng ka ho lieha ho buuoa ka ho feletseng ha lengole la lengole (TKR) .
Qetellong, bafuputsi ba senoletse hore bakuli ba 72,6 lekholong ba tšoaroa ka ho buuoa ka TKR ea Synvisc ho pholletsa le thuto. Le hoja ho ne ho sa tsejoe litla-morao tse tebileng kapa tsa nako e telele, batho ba robeli ba ile ba e-ba le liphello tse bohloko tsa ho ruruha ka mor'a liente. Ha ho letho le neng le nkoa e le la bohlokoa
E itšetlehile ka Bophirimela ba Ontario le McMaster Universities Osteoarthritis Index ( WOMAC ), tlhahlobo e sebelisetsoang ho lekanya maemo a bohloko a utloisisoang, batho ba Synvisc ba na le hoo e batlang e le karolo ea 20 lekholong ea theoha mahlomoleng ha ba bapisoa le ba sebakeng se seng.
Mofuta oa lefu la masapo oa lefutso ke kajeno mofuta o tloaelehileng oa ramatiki United States, o amang batho ba ka bang limilione tse 13,7. Ho itšetlehile ka liphuputso tsa lithuto, Synvisc e nkoa e le mokhoa o bolokehileng le o sebetsang oa ho phekola bohloko le bokooa molokong ona 'me, ha o sebelisitsoe hantle, ho ka thusa ho lieha ho buuoa ka lilemo tse tharo kapa ho feta.
> Mohloli:
> Tsamaiso ea Tsamaiso ea Lijo le Meriana ea US. (2008) "Proposed Synvisc-One Summary of Safety le katleho." Silver Spring, Maryland.