Boemong bo bitsoang chemotherapy-bo bakoang ke lefu la methapo ea meriana (CIPN), lithethefatsi tse itseng tse sebelisetsoang ho phekola kankere li baka tšenyo ho methapo ea hau ea meriana.
Maqhubu a hao a mongobo a na le matšoao a tsoang bokong ba hao le mokokotlo oa mokokotlo ho mesifa ea hao ho potlakisa ho tsamaea. Li boetse li na le boitsebiso bo nang le boitsebiso bokong ba hao le mokokotlo oa mokokotlo.
Matšoao
K'hemik'hale e bakoang ke phekolo ea phekolo ea qoqotho e ka 'na ea baka matšoao a fapa-fapaneng ho itšetlehile ka hore na ke methapo efe ea meriana e amehang.
Mehlala ea matšoao a tloaelehileng a kenyelletsa:
- Boitšoaro
- Ho bapisa, joaloka "likhohlo le nale" mehopolo
- Ho chesa matsohong le maotong
- Ho thunya kapa ho hlaba bohloko bo tebileng bo ka bang teng ka hare kapa bo tsitsitseng
- Ho leka-lekanya mathata
- Ho tlohela lintho
- Ho tlōla
Kaha methapo ea meriana e boetse e laola senya le sefuba, phekolo ea meriana ea qoqotho e bakoang ke chemotherapy e ka 'na ea lebisa ho tiisetso kapa mathata a ho phutha.
Lisosa
Ho ea ka American Cancer Society, mona ke lithethefatsi tsa chemo tse amanang haholo le ho baka CIPN:
- Lithethefatsi tsa platinum tse kang Cisplatin, Carboplatin, le Oxaliplatin
- Mekotane e kang Taxol (paclitaxel), Taxotere (docetaxel), le Jevtana (cabazitaxel)
- Li-Epothilone tse kang Ixempra (ixabepilone)
- Li-alkaloids tsa limela tse kang vinblastine, vincristine, vinorelbine le etoposide (VP-16)
- Thalomid (thalidomide), Revlimid (lenalidomide), le Pomalyst (pomalidomide)
- Velcade (bortezomib) le Kyprolis (carfilzomib)
- Halaven (eribulin)
Ha e le hantle, hobane feela u fuoa e le 'ngoe kapa tse ling tsa lithethefatsi tse ka holimo tsa chemo, ha ho bolele hore u tla hlahisa CIPN.
Ho na le mefuta e mengata e kotsing, joaloka tekanyo ea lithethefatsi, motsoako oa lithethefatsi o fanoeng, le lilemo tsa hau.
Thibelo
Haeba neuropathy ea hao e e-ba mpe haholo, e ka 'na ea se ke ea ama bophelo ba hau feela, empa e ka kena-kenana le phekolo ea hau, haholo-holo haeba u hloka ho sebelisa chemotherapy e tlaase ka lebaka la matšoao a hao a fokolisang.
Ka bomalimabe, ha ho na phekolo e amohelehang ea FDA bakeng sa ho thibela lefu la neuropathy e amanang le chemotherapy. Leha ho le joalo, ho 'nile ha e-ba le mefuta e mengata ea phekolo e thibelang; le hoja bopaki ba saense bo ba tšehelitseng bo ka ba bobebe, bo sa tsejoe kapa bobeli.
L-Glutamine
Seo se boletse hore sethala se seng se bontšitsoeng (mohlomong ka mokhoa o tsitsitseng ho feta ba bang) ho ba le tšireletso ho methapo ke L-glutamine. Ho lumeloa hore tlatsetso ena e sebetsa ka ho etsa sekoahelo maotong matsohong a hao, maoto le tšitšili ea lijo. "Tšenyo" ena e fokotsa kapa e senya tšenyo e ka bakoang ke chemotherapy.
Ha e le hantle, thuto ea ho hlahloba ka Tlhahlobo e Bohlokoa ho Oncology / Hematology e boletse L-glutamine e le tšepiso ea ho thibela tšoaetso le ho tiea ha phekolo ea meriana e bakoang ke phekolo ea meriana ea chemotherapy.
Ha e le hantle, le hoja glutamine e bonahala e sireletsehile haholo 'me e bonahala e sa kena-kenane le phekolo ea kankere (bonyane lithuto ho fihlela joale) ke habohlokoa ho buisana le ngaka pele u nka setlatse kapa vithamine.
Lebaka ke hore li-supplement le livithamini, ha li atisa ho bitsoa "tsa tlhaho," ha li bolokehe kamehla. Ha e le hantle, phekolo e 'ngoe ea "tlhaho", acetyl - l - carnitine, e neng e nahana hore e ka' na ea thusa nakong e fetileng, e ka 'na ea e-ba mpe le ho feta bakeng sa chemotherapy.
Ho feta moo, lintho tsena "tsa tlhaho" li ka sebelisana le kankere, esita le ho fokotsa katleho ea tsona.
Ka kakaretso, haeba ngaka ea hao e lumellana hore glutamine e ka ba e bolokehileng ebile ea u thusa, botsa hore na ke tekanyo efe eo ae khothalletsang. Tekanyo e tloaelehileng ke limilimithara tse 15 ka letsatsi, empa nako ea ho qala sena le nako e telele ea ho sebelisa setsi sena se tla fapana ho ea ka ts'ebetso ea hau ea chemotherapy.
Mefuta e meng ea phekolo e thibelang
Mefuta e meng ea phekolo e ka thusang ho thibela CIPN, e kenyelletsa vithamine E le omega-3 fatty acids, le hoja hape, saense e ts'ehetsa katleho ea eona e lekanyelitsoe. Ntle le lisebelisoa le li-vithamine, meriana ea mangolo e ka thusang ho thibela CIPN e kenyeletsa
- Ba bang ba nang le bothata ba ho tepella maikutlo joaloka Effexor (venlafaxine)
- Meriana e meng ea ho loantša lefu joaloka Tegretol (carbamazepine)
Lentsoe le Tsoang ho
Meriana ea phekolo ea kelello ea chemotherapy e ka ba bothata bo sitisang, eseng feela ka bobebe bo bakoang empa hape hobane bo ka ama tšebetso ea hau ea phekolo ea kankere.
Leha ho le joalo, ho sa tsotellehe hore na ke eng, ke habohlokoa haholo ho tsebisa ngaka ea hao haeba u e-na le matšoao afe kapa afe a lefu la ho fokola ha pelo-'me ka potlako ho ba molemo, ho rarolla bothata hona hang-hang ho ka thibela lefu la pelo hore e se ke ea lula e le teng.
> Mehloli:
> Mokhatlo oa Kankere oa Amerika. Pherefere ea Neuropathy e Etsoang ke Chemotherapy.
> Brami, C., Bao, T., le G. Deng. Lihlahisoa tsa tlhaho le litlhare tse tlatsanang bakeng sa phekolo ea meriana ea phekolo ea meriana ea chemotherapy: Tlhahlobo e hlophisitsoeng. Tlhahlobo e Bohlokoa ho Oncology le Hematology . 2016. 98: 325-34.
> Dana Farber Cancer Institute. Ho Fokotsa Pherekano Matšoao a Neuropathy. E fihlile ka 03/05/16. http://www.dana-farber.org/Health-Library/Alleviating-Peripheral-Neuropathy-Symptoms.aspx
> Wang, W., Lin, J., Lin, T. le al. Moriana o nang le molomo o atlehile ho thibela boloetse ba pelo ea pelo ea oxaliplatin e bakoang ke kankere e hlabang. Oncologist . 2007. 12 (3): 312-9.