The Connection ea Estrogen
Na u ne u tseba hore ho ba le migraine ho ka fokotsa kotsi ea ho ba le kankere ea matsoele nakong e tlang?
Le hoja migraine le kankere ea matsoele ke maemo a ikhethang a bongaka, ho na le ntlha e le 'ngoe e kholoang kapa e li kopanya -homone ea ho kopanela liphate, estrogen.
Kankere ea Lebese le Estrogen
Kankere ea matsoele e hlaha ha lisele tsa kankere tse fetoletsoeng li ntse li hōla ka mokhoa o sa laoleheng, hangata li le mokhoeng le maqeba a liphatsa tsa matsoele.
Bophelo bo boholo ba bophelo bohle ho estrogen bo eketsa kotsi ea kankere ea matsoele. Kahoo eng kapa efe e eketsang estrogen 'meleng e ka' na ea eketsa kotsi ea kankere ea matsoele. Mehlala ea maemo a eketsang estrogen a kenyelletsa:
- Nako ea nako e telele ea ho ea khoeling (ho qala pele ho lilemo li 12, ho ikhula khoeli ka mor'a lilemo tse 55)
- Botenya bo bongata ba Postmenopausal, moo li-adipose kapa mafura a mafura a fetoloang ho estrogen
- Phekolo ea Hormone e kopantseng
Migraines le Estrogen
Liketsahalo tsa migraine li fapana le basali ka lebaka la ho ea khoeling, 'muso oa bona oa meriana, le hore na ba imme. Phetoho ena ea maqhubu a migraine le matla a maholo a ka amahanngoa le maemong a mosali a feto-fetohang a estrogen.
Ka mohlala, makhetlo a migraine a eketseha hang kapa pele nakong ea ho ea khoeling (ha a ea khoeling ), ha maemo a estrogen a fokotsehile. Ka lehlakoreng le leng, basali ba bangata ba fumana khatholoho ea migraine ea bona nakong ea bobeli ba boraro ba boimana, 'muso o phahameng oa estrogen.
Migraines le Cancer ea Sefuba: Khohlano ea Khang
Li-migraine le kankere ea matsoele ke li-mediated mediator, kahoo ho ka 'na ha e-ba le kamano pakeng tsa liketsahalo tsa migraine le kotsi e tlaase ea ho ba le kankere ea matsoele. E 'ngoe ea lithuto tsa pele ho hlahloba kamano ena e ne e le Cancer Epidemiology, Biomarkers le Thibelo.
Phuputso ena e fumane hore basali ba nang le boitsebiso ba migraine ba ipolelang hore ba na le karolo ea 33 lekholong ba fokotsa kotsi ea ho hlahisa li-hormone-receptor tse nang le tšoaetso e ntle ea li -ductal le lobular carcinoma mmuso oa postmenopausal. Leha ho le joalo, thuto ha ea ka ea laola bakeng sa tšebeliso ea li- NSAID , sehlopha se tloaelehileng sa meriana e sebelisetsoang ho phekola migraine - 'me lithuto tse' maloa li bontšitse hore tšebeliso ea NSAID e ka 'na ea e-ba kotsi ea kankere ea matsoele ea tlase.
Phuputso e 'ngoe Lefapheng la Clinical Oncology le eona e fumane hore basali ba postmenopausal ba nang le boitsebiso ba migraine ba ipolelang hore ba na le kotsing e fokolang ea kankere ea matsoele. Phuputso ena e fumane karolo ea 17 lekholong ea kotsi ea ho ba le kankere e ntle ea li-hormone-receptor. Ho phaella moo, kotsi ena e fokotsehileng e ne e ikemetse ka tšebeliso ea NSAID, hammoho le tšebeliso ea joala le caffeine, tse peli tse tloaelehileng tse hlahisang migraine .
Ka 2014, phuputso e 'ngoe Kankere ea Causes and Control e ile ea hlahloba linyeoe tse fetang 700 tsa kankere ea matsoele. Bafuputsi ba fumane hore ha ho bapisoa le basali ntle le histori ea migraine, basali ba nang le histori e mengata ea migraine (lilemo tse ka holimo ho 30) ba na le kotsing e ka tlaase ho karolo ea 60 ea ho ba le kankere ea matsoele ea kankere ea matsoho ea estrogen.
Ho phaella moo, basali ba neng ba e-na le migraine ea bona pele ba le lilemo li 20 ba ne ba e-na le kotsi ea ho ba le kankere ea matsoele ea tumello ea estrogen (bobeli le ho lobula) ha ba bapisoa le bao e seng bo-migraine (basali).
Qetellong, basali ba nang le migraine ba nang le aura ba ne ba boetse ba se na monyetla oa ho hlahisa kankere ea matsoele ea estrogen e nang le kankere ea matsoele.
Ka lehlakoreng le leng la thuto ea 2013 ka Lebaka la Kankere le Tlhokomelo ea Kankere ho feta ba 7 000 ba nang le migraine ha ba fumane kamano leha e le efe ea bohlokoa pakeng tsa migraine le kotsi ea kankere ea matsoele.
Ha e le hantle, lithuto tsena kaofela li na le meeli, 'me haeba li khethoa li ka hlalosa liphello tsa tsona tse khethehileng. Setšoantšo se seholo ke hore taba ena le kamano e thahasellisang e lokela ho hlahlojoa haholoanyane.
The Bottom Line
Hopola, khokahanyo e fana ka maikutlo a kamano kapa bokamano.
Ha ho bolele hore boemo bo bong ba bongaka bo baka ka ho toba kapa bo sitisa e mong. Ho hlokahala lithuto tse ling tse tsoelang pele ho hlahloba kamano e rarahaneng pakeng tsa kankere ea matsoele le migraine.
Sena se Bolela'ng ho 'na?
Tsoela pele u lula u tsitsitse molemong oa tlhokomelo ea hau ea bophelo. Buisanang ka lisosa tsa kotsing ea kankere ea matsoele le ngaka ea hau. Hlahloba hore na bophelo bo botle ba bophelo, bo kang boima ba 'mele, bo ka fokotsa migraine ho utloa bohloko ho phaella kotsing ea kankere ea matsoele.
Lisebelisoa:
Dumitrescu R, Cotarla I. Ho utloisisa kotsi ea kankere ea matsoele: re eme hokae ka 2005? J Cell Mol Med 2005; 9: 208-21
Harris RE, Chlebowski RT, Jackson RD, et al. Kankere ea matsoele le lithethefatsi tse seng khahlanong le ho ruruha: sepheo se hlahang ho Women's Health Initiative. Cancer Res 2003; 63: 6096-101.
Li CI, Mathes RW, Bluhm EC, Caan B, Cavanagh MF, Chlebowski RT. Histori ea migraine le tšoaetso ea kankere ea matsoele har'a basali ba ka morao-rao. J Clin Oncol . 2010 Feb 20; 28 (6): 1005-10.
Mathes RW et al. Migraine ho basali ba postmenopausal le kotsing ea kankere ea matsoele e hlaselang. Kankere Epidemiol Biomarkers Pele . 2008 17: 3116-3122.
Nako ea mariha, Rexrode KM, Lee IM, Buring JE, Tamimi RM, Kurth T. Migraine le kotsing e latelang ea kankere ea matsoele: motho ea batlang ho ithuta ka sehlopha. Cancer Causes Control . 2013 Jan; 24 (1): 81-9.