Li-antiantibodies ke liprotheine tse hlahisoang ke 'mele ea' mele oa hao oa 'mele. Mohlomong ua tseba hore sesole sa hau sa 'mele se etselitsoe ho loantša tšoso joaloka likokoana-hloko le libaktheria tse kenang' meleng oa hao. Empa motlakase o fetola tlhaselo ea oona ka ntho e fosahetseng: Ho e-na le ho hlasela bahlaseli ba tsoang linaheng tse ling, li-autoantibodies li hlasela likarolo tsa 'mele oa hao ka phoso.
Ha ba etsa sena, li-autoantibodies li baka ho ruruha le ho senya tsamaiso leha e le efe ea 'mele eo ba e hlaselang. Tšenyo ena e fella ka seo re se bitsang " boloetse ba autoimmune " -ka utloahala, "auto" e bolela "boithati." Li-autoantibodies li hlaha pele matšoao a lefu lena a hlakile.
Ke Hobane'ng ha 'Mele oa Hao o Etsa Li-Autoantibodies?
Ha ho hlakile. Li-genetics li ka 'na tsa kenya letsoho mosebetsing ona, joalo ka maemo a tikoloho. Empa bafuputsi ha ba elelloe hore na ke hobane'ng ha batho ba bang ba nang le liphatsa tsa lefutso le / kapa lintho tse tšoanang tse hlahisang tikoloho ba qala ho etsa li-autoantibodies ebe joale ba tsoela pele ho hlaolela boloetse bo sa khaotseng, ha ba bang bona ba sa se bone. Ka lefu lena le pholileng , ka mohlala, 'mele oa hao o arabela ho kenngoa ha protheine ea gluten lijong tseo u li jang ka ho etsa autoantibodies tse ntan'o tsoela pele ho hlasela lera la mala a hao a manyenyane.
Hona joale, batho ba bangata ba nang le lefu lena le leng le le leng ba na le liphatsa tsa lefutso tse peli tse lebisang ho boemo bona.
Empa likokoana-hloko tsena tseo ho thoeng ke li- celiac li tloaelehile haholo, 'me karoloana e nyane feela ea ba nang le liphatsa tsa lefutso ba qala ho etsa li-autoantibodies mme ba tsoela pele ho hlaolela lefu lena le leng. Kahoo, ho totobetse hore ho na le ntho e 'ngoe e bapalang e etsang hore' mele oa hao o qale ho etsa autoantibodies. Lipatlisiso li tsoelapele ho fumana hore na "ntho" eo e ka ba efe.
Ke Eng Seo Nka se Tsebang ho se Tseba ka Autoantibodies?
Li-autoantibodies tse ling li hlasela setho se itseng-ka mohlala, li-autoantibodies li hlasetsoeng ke lefu lena le le maling a malinyane, li-autoantibodies ka lefu la qoqotho le lekaneng le hlaselang lefu la qoqotho, le li-autoantibodies lefapheng la 2 la tsoekere le hlaselang lisele tsa hlahisoang ke insulin liphakeng.
Hangata li-autoantibose tsa mofuta ona li lebisa matšoao a tobileng a ka thusang ngaka ea hao hore e fumane hantle. Ho etsa mohlala, ho na le matšoao a mangata a lefu lena a lekaneng, empa matšoao a tloaelehileng haholo, a kenyeletsang mathata a ho senya lijo le khaello ea mali, a ka fana ka leseli la ho thusa ho hlahlojoa.
Li-antiantibodies tse ling li bitsoa "systemic," e bolelang hore ba hlasela libakeng tse fapaneng ho pholletsa le 'mele oa hau. Tsena li ka hlahisa matšoao a mangata a tloaelehileng, a kang bohloko ba mokuli le li-rashes, tse etsang hore boemo bo itseng bo be boima ho feta ho bo hlahloba.
Ka mohlala, ho ka 'na ha e-ba thata ho hlalosa phapang lipakeng tsa lefu le ipatileng la lupus le fibromyalgia, tseo lingaka li li lumelang hase boemo bo ikemetseng. E le ho thusa ho etsa hore ho fumanoe lefu lena, lingaka li ka laela liteko tsa mali li batla li-autoantibodies tse bitsoang anti-nuclear antibodies, kapa ANA. Tsena ke li-autoantibodies tse hlaselang likarolo tsa nuclei ea lisele tsa hau, 'me hoo e batlang e le motho e mong le e mong ea nang le lupus o tla ba le maikutlo a nepahetseng bakeng sa bona, ha a bapisoa le karolo e nyane feela ea ba nang le fibromyalgia.
Lisebelisoa:
Arbuckle MR et al. Ntlafatso ea li-autoantibodies pele ho ts'oaetso ea meriana ea systemic lupus erythematosus. New England Journal of Medicine . 2003 Oct 16; 349 (16): 1526-33.
Dönmez S et al. Ho itšireletsa ka boloetse ba lefu la lefu la ho ruruha ha maikutlo ho amana le matšoao a bakoang ke bakuli ba fibromyalgia le tšusumetso ea bona ho tšoenyeha, ho tepella maikutlong le ho tsitsa: thuto ea ho bapisa. Rheumatology ea Kliniki le Tlhahlobo . 2012 Nov-Dec; 30 (Tlhaloso ea 6): 65-9.
Fujii T. Tsela e tobileng le e tobileng ea likokoana-hloko tsa li-autoantibodies matšoao a tsamaiso ea 'mele. Allergology International . 2014 Dec; 63 (4): 515-22.
Hu ZD le al. Autoantibodies ka lefu la pele ho meriana ea boithaopo. Clinica Chimica Acta: International Journal of Clinical Chemistry . 2014 Nov 1; 437: 14-8.