Hyspothyroidism e ka hlaha ka mabaka a sa tšoaneng, ho tloha tlhaselong ea tlhaho ea qoqotho ea qoqotho (e bitsoang Hashimoto's thyroiditis) ho noa meriana e kang lithium. Hyspothyroidism e ka 'na ea boela ea e-ba letšoao la pele la bothata bo ka sehloohong ba pituitary mochine.
Ho utloisisa "hobaneng" ka mor'a hore motho a fumane lefu la hypothyroidism ke habohlokoa ho tsoela pele ka morero oa phekolo.
Lebaka ke hobane ha batho ba bang ba ka hloka phetoho ea qoqotho ea bophelo bohle ba hao, ba bang ba ka ba le nako ea nakoana ea hypothyroidism (mohlala, postpartum thyroiditis), ba lokela ho khaotsa ho noa meriana, kapa ba hloka liteko tse eketsehileng tsa ho hlahloba ho tšoana le litšoantšo tsa mohala oa pituitary.
Ntho e Tloaelehileng
Hashimoto's thyroiditis ke sesosa se ka sehloohong sa hypothyroidism United States.
Hashimoto's Thyroiditis
Hashimoto's thyroiditis ke boloetse bo ikemetseng bo amang lefu la thyroid. Hashimoto, li-antibodies li arabela khahlanong le liprotheine liphatsong tsa qoqotho tsa hau, li baka tšenyo e fokolang ea sekhahla ka boeona, e leng se etsang hore se se ke sa hlahisa lihomone tsa qoqotho tseo 'mele oa hao o li hlokang.
Hashimoto's thyroiditis e atile haholo ho basali, 'me ha e ntse e ka ba teng ka nako leha e le efe, e tloaelehile ha batho ba ntse ba hōla. Bakeng sa basali, Hashimoto o atisa ho hlaha nakong ea bokhachane, kamora ho pepa, kapa nakong ea nako ea ho ipolaea.
Mabaka a mang
Ntle le lefu la Hashimoto, lisosa tse ling tsa hypothyroidism li kenyelletsa:
Ho buuoa
Batho ba nang le hyperthyroidism, lihlopha tsa qoqotho kapa kankere ea qoqotho li ka 'na tsa hloka ho buuoa. Haeba mofuta o mong le o mong oa qoqotho o tlosoa ka opereishene, motho o tla ba hypothyroid 'me a hloka meriana ea qoqotho ea bophelo bo botle ka ho fetisisa bophelong ba hao.
Haeba feela karolo ea qoqotho ea qoqotho e tlosoa, ho na le monyetla o motle oa hore o tla khona ho etsa hormone e lekaneng ea qoqotho.
Mahlaseli
Ho e-na le ho buuoa ka qoqotho kapa meriana ea antithyroid, batho ba bang ba nang le hyperthyroidism ba tšoaroa ka iodine e nang le radioactive, e tla senya lekhalo la qoqotho, e fa motho hypothyroid. Batho ba fumanoang kalafo ea mahlaseli bakeng sa Hodgkin's lymphoma kapa kankere ea hlooho le molala ba kotsing ea ho hlahisa hypothyroidism.
Thyroiditis
Thyroiditis e hlalosa qoqotho ea ho ruruha ha qoqotho 'me ke nako e tloaelehileng ea maemo a sa tšoaneng a qoqotho. Lefu la Hashimoto (joalokaha ho boletsoe ka holimo) ke mofuta o tloaelehileng ka ho fetisisa oa thyroiditis 'me o bakoa ke tlhaselo ea motho ka mong.
Mohlala o mong oa Thyroiditis ke lefuba thyroiditis (e boetse e bitsoa de Quervain's thyroiditis), e nkoang e bakiloe ke vaerase. Le mofuta ona oa thyroiditis, motho o na le hyperthyroidism e lateloa ke hypothyroidism, ho phaella ho qoqotho ea qoqotho e bonolo.
Lithethefatsi tse ling
Meriana e meng e ka baka hypothyroidism. Meriana ena e kenyelletsa:
- Lithium
- Amiodarone
- Thionamides (lithethefatsi tsa li-antithyroid)
- Interferon-alpha
- Interleukin-2
- Lithethefatsi tse ling tsa kankere (tyrosine kinase inhibitors le checkpoint inhibitor immunotherapies)
Iodine e Feteletseng kapa Bofokoli
Li-iodine tse ngata haholo (ka mohlala, ho tsoa lijong tse nang le lisebelisoa tsa lijo tse nang le kelp) li ka baka kapa ho mpefatsa hypothyroidism. Ho phaella moo, ho haelloa ke iodine, e bonoang ho batho ba bang linaheng tse sa tsoetseng pele ho ka baka hypothyroidism. Iodine e hlokahalang bakeng sa tlhahiso ea hormone ea thyroid, 'me e fumanoa lijong, joaloka lihlahisoa tsa lebese, khoho, nama ea khomo, nama ea kolobe, tlhapi le letsoai la iodized.
Congenital Hypothyroidism
Bana ba bang ba tsoaloa ba se na qoqotho kapa ba na le bothata ba qoqotho feela. Kaha ha ho na qoqotho ea qoqotho (kapa ha e lekaneng) ho hlahisa hormone ea thyroid, hypothyroidism e qala, e leng e tebileng 'me e hloka phekolo ka pilisi ea thyroid.
Pituitary Gland Bothata
Sepheo sa pituitary se ka boko 'me se susumetsa liphatsa tse ling tse ka hare ho' mele, joaloka lesela la qoqotho, ho lokolla hormone. Haeba lesela la pituitary le senyehile ke boko ba boko, mahlaseli a kotsi, kapa ho buuoa ke boko, e ka 'na ea se ke ea sebetsana ka ho lekaneng bakeng sa ho bontša tšoelesa ea thyroid. Sena se ka etsa hore ho be le qoqotho e sa sebetseng ea qoqotho. Mofuta ona oa hypothyroidism o bitsoa central or secondary hypothyroidism.
Maloetse a tšoaetsanoang
Hangata maloetse a itseng, a kang hemochromatosis, a ka beha lintho tse sa tloaelehang (tšepe, tabeng ea hemochromatosis) mokokotlong oa pituitary, o bakang hypothyroidism bohareng, kapa ka tlaase ho tloaelehileng, mokokotlo oa thyroid, o bakang hypothyroidism e ka sehloohong.
Ntle le hemochromatosis, sarcoidosis e ka etsa hore phallo ea granuloma e kenngoe ke qoqotho. Ho boetse ho na le boemo bo sa tloaelehang bo bitsoang fibrous thyroiditis (kapa Riedel's thyroiditis), eo lisele tsa 'mele li ntseng li fetoha lisele tse tloaelehileng tsa qoqotho.
Liphatsa tsa lefutso
DNA ea hau e phetha karolo ea ho hlahisa autoimmune hypothyroidism, 'me sena se tšehetsoa ke lithuto tse' maloa.
Ka mohlala, phuputso e 'ngoe ea Jeremane e fumane kotsing ea bobeli ba ho hlahisa Hashimoto's thyroiditis ho bana le kotsi e fetang 21 ho banab'eno ba nang le Hashimoto's thyroiditis.
Ha li sheba liphatsa tsa lefutso tse amanang le Hashimoto, bo-rasaense ba fumane liphetoho liphatseng tsa lefutso tsa leukocyte antigen (HLA), T-cell receptors, le limolek'hule tse ling tse amehang tsamaisong ea 'mele ea ho itšireletsa mafung.
E le hore u tsoele pele ho tšehetsa karolo ea liphatsa tsa lefutso ho ntlafatsa Hashimoto's thyroiditis, li-genetic syndromes, Turner syndrome le Down syndrome, li na le tekanyo e fetang e lebelloang ea lefu la qoqotho le ikhethang, haholo-holo Hashimoto's thyroiditis.
Leha ho le joalo, bohle ba boletse, ke habohlokoa ho hopola hore liphatsa tsa lefutso tsa hau ke ntho e le 'ngoe e thusang ho bolela kotsi ea ho hlahisa hypothyroidism. Ho na le mabaka a mangata a mangata (tikoloho) a kenang papali, joaloka ho ima kapa ho noa meriana e itseng.
Qetellong, ke motsoako oa liphatsa tsa lefutso le mohloli oa tlhaho oa tikoloho o bolelang esale pele kotsi e ikhethang ea motho ea ho theha hypothyroidism.
Mathata a Tloaelehileng a Likotsi
Lintho tse eketsang kotsi ea motho ea ho theha hypothyroidism li kenyelletsa:
- Ho ba mosali
- Ho ba motho ea tsofetseng
- Ho ba Caucasian kapa Asia
- Ho ba le histori ea malapa ea Hashimoto's thyroiditis kapa lefu le leng le le leng la ho itšehla thajana
- Ho ba le histori ea botho ea lefu le leng le le leng (ka mohlala, ho se sebetse ha adrenal, lefu la ramatiki kapa lefu la tsoekere la mofuta oa 1)
- Ho ba le moimana kapa ka morao
- Ntho e ngata haholo kapa e nyenyane haholo ea tšebeliso ea iodine
- Tšoaroa ka iodine ea radioactive
- Re fumane mahlaseli a mokokotlo ho molaleng kapa ka lebokoseng
- O ile a buuoa ka qoqotho
- Ho tšoaroa ka meriana e itseng (mohlala, lithium ea lefu la ho ferekana kelellong)
Ho Ntlafatsa Lintho Tsa Kotsi
Ho thahasellisang ke hore r esearch e fana ka maikutlo a hore khaello ea selenium e ka amahanngoa le ho hlahisa Hashimoto's thyroiditis le hypothyroidism. Ho feta moo, ho ba le bothata bo boholo ba hlooho, joaloka migraine, bo fumanoe bo amahanngoa le kotsi e eketsehileng ea hypothyroidism, haholo-holo ho basali ba mahlahahlaha.
Ho ntse ho sa tsejoe hantle hore na ho tsuba ho ama tsela ea qoqotho joang, le hoja e ka 'na ea e-ba e rarahaneng. Le hoja liphuputso li bontša hore ho tsuba koae ho eketsa kotsi ea hypothyroidism ho batho ba nang le Hashimoto's thyroiditis, lipatlisiso tse ling li bontša hore ho tsuba ho hlile ho amana le ho ata ha hypothyroidism le ho ata ha hyperthyroidism.
> Mehloli:
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