Na ho na le Kamano Pakeng tsa Tlhaselo ea AD le Tsela ea Hao ea ho Utloa?
Yuck! Ho fofonela hoe? Hantle, ho ea ka bafuputsi ba bang, bokhoni ba hau ba ho arabela potso eo bo ka 'na ba bolela menyetla ea hau ea ho hlaolela lefu la Alzheimer .
Liphuputso tse ngata tsa lipatlisiso lilemong tse 20 tse fetileng li bontšitse hore ho na le kamano pakeng tsa ho se khone ho lemoha monko le ho fokotseha ha tsebo. Liphuputso tse 'maloa le tsona li bontšitse kamano ea pele ho moo maikutlo a fosahetseng a batho ba neng ba se na ' dementia 'a boletse hore batho ba tšoanang le bona ba ka ba le matšoao a lefu la Alzheimer ka mor'a nako.
Ka mohlala, phuputso e 'ngoe e amanang le batho ba ka bang 3 000 ba pakeng tsa lilemo tse 57 ho isa ho tse 85 ka kamohelo e tloaelehileng e ileng ea ithutoa ka lilemo tse hlano. Bafuputsi ba fumane hore ho fokotsa bokhoni ba ho bolela phapang pakeng tsa monko o ne o amana haholo le kotsi ea ho ba le 'dementia' ka makhetlo a fetang a mabeli.
Bafuputsi ba boetse ba shebile bofokoli bo bonolo ba ho nahanisisa . Bothata bo bonolo ba ho ba le ts'ebeliso ea kelello ke boemo boo batho ba nang le bothata ba bona ka mesebetsi ea ho hopola , ho tsepamisa mohopolo , ho hopola le ho buisana le tsebo joaloka ho tseba ho fumana mantsoe . Likarolo tse ling, empa eseng tsohle, tse nang le bokooa bo fokolang ba ho nahanisisa li tsoela pele ho lefu la Alzheimer.
Phuputsong ea lilemo tse hlano, bo-rasaense ba ile ba shebella batho ba 589 ba neng ba lula malapeng a bona. Ha ho le ea mong oa barupeluoa ea neng a e-na le bothata bo fokolang ba kutloisiso qalong ea thuto. Ts'ebetso ea motho e mong le e mong ea sebetsang hammoho le bokhoni ba bona ba ho bona monko o ile oa lekoa qalong ea thuto, 'me selemo le selemo ka mor'a moo.
Liphetho? Barupeluoa ba bontšitseng bothata ba ho lemoha monko o monate ba ile ba fokotseha likarolo tsa liteko tsa ts'ebetso ea ts'ebetso. Ka mantsoe a mang, ho sitoa ho khetholla monko o bolelang esale pele hore na ke mang ea tla hlahisa matšoao a ho se utloisise hantle.
Liphuputso tse ling li hlokometse hore ho se sebetse ha mokhoa o hlophisehileng ho boleloa esale pele nakong ea bokamoso boemong ba MMSE le hore bokhoni bo matla ba ho khetholla monko bo ne bo amana hantle le mohopolo o potlakileng le o liehang, ho bua ka mokhoa o phollatsi , bokhoni ba visuospatial , le bokhoni ba ho tseba.
Ke Eng e Etsang Hore Maikutlo a Ho Utloa a Utloe a Hlasetsoe ke Maloetse a Alzheimer?
Ke'ng e bakang tahlehelo ee? Liphuputso li bonahala li bontša hore maikutlo a monko a ameha ka ho ba teng ha beta amyloid protheine libakeng tsa boko bo re thusang ho lemoha le ho bona monko o monate. Phuputso e 'ngoe e bontša hore libaka tsena tsa boko ke moo liprotheine li bokellang pele, ho senya mohopolo oa monko pele ho ts'ebetso ea ts'oaetso ho ameha.
Liphuputso tse ngata li bontšitse ho hokahanngoa ho hoholo pakeng tsa lefu la Alzheimer le patholose ea liprotheine tse matlafatsang (mokhoa oa rona oa ho fofonela).
Phuputso e 'ngoe e ile ea hlahloba liphello tsa li-autopsies tse 130' me ea fumana hore maemong 'ohle a lefu la Alzheimer, ho ne ho e-na le bothata ba tau mokhoeng oa boko.
Phuputso ea bobeli ea lipatlisiso e fumane hore ha ho hlahlojoa li-autopsies tse 273, ho ne ho e-na le kamano e phahameng pakeng tsa mohaho o tsitsitseng oa tsamaiso le ho ba le tšenyo ea boko bo amanang le lefu la Alzheimer.
Liphuputso li boetse li bontša hore ha lefu la Alzheimer le ntse le tsoela pele, matla a ho fofonela a fokotseha.
Na ho Lahleheloa ke Smell Ho Hlahisa le Mefuta e meng ea Dementia?
Bafuputsi ba fumane hore lefu la Alzheimer le lefu la ' mele la' mala oa Lewy le bontšitse liphello tse kholo ka kutloisiso ea monko, ha batho ba nang le tšelo ea mali ea supranuclear le ea corticobasal e senyehang ha ba bontše ho holofala.
Na Botsofali bo ka ba Lebaka la ho Nahana ha ho Utloa?
Ho sa tsotellehe ho senyeha ha bopaki bo bonahalang bo le teng, sehlooho se seng sa lipatlisiso se hlahisa lipotso. Phuputsong ena, bo-rasaense ba ile ba hlahloba lithuto tse ngata tse entsoeng ka kutloisiso ea monko le ts'ebetso ea eona ea ho fokotseha ha ts'ebetso ea ts'ebetso 'me ba etsa qeto ea hore lipatlisiso tse ngata li hlōlehile ho bontša bopaki bo matla ka lebaka la libopeho tsa lithuto. E 'ngoe ea lintho tse tšoenyang ke hore ha batho ba ntse ba le lilemo li kholo, mohopolo oa monko o oa. Ka lebaka lena, lipatlisiso li tlameha ho nka ntlha ena e le hore lipatlisiso li bontše hore ho hlōleha ho khetholla monko ha hoa tsosoa ke lilemo empa ho e-na le ts'ebetso ea boko bo amanang le ho lahleheloa ke ts'ebetso ea ts'ebetso.
Ho itšetlehile ka palo e kholo ea lipatlisiso e entsoeng, leha ho le joalo, e ntse e ka 'na ea e-ba le thae pakeng tsa maikutlo a futsanehileng a monko le ho fokotseha ha tsebo.
Na U Lokela ho Lekola Tsela ea Hao ea ho Utloa Hore na U Tla Fumana Haeba U Kotsing ea Tlhahlobo ea Dementia?
Tlhahlobo e bonolo ea monko ha e khothalletsoe e le tsela ea ho khetholla ba kotsing ea ho ba le 'dementia' nakong ena, le hoja ho ka khoneha ho kenyeletsoa e le karolo ea liteko tsa betri. Seo se ka atlehang nakong ena se lebisa tlhokomelo ho seo u ka se etsang ho fokotsa kotsi ea ho ba le 'dementia', e kang mosebetsi oa kelello , ho ikoetlisa 'meleng, le ho ja lijo tse nepahetseng.
Lentsoe ho
Haeba u tšoenyehile ka mohopolo oa hau mme u lemoha ho fokotseha ha bokhoni ba hau ba ho lemoha kapa ho khetholla monko, o ka nka teko ea lehae e kang teko ea SAGE dementia screening . Etsa bonnete ba hore o tla rera nako ea ho buisana le ngaka ka lipatlisiso tsa hau, kaha ho na le lisosa tse ngata tsa ho lahleheloa ke mohopolo, hammoho le melemo e mengata ea ho lemoha lefu la 'dementia pele '.
Lisebelisoa:
Archives of General Psychiatry. 2007; 64 (7): 802-808. Ho khetholla ka mokhoa o hlollang le ho ba le tšusumetso e mpe ea ho hloka kutloisiso ho nahanisisa nakong ea botsofali.
> Goette, W., Werry, A. le Schmitt, A. (2017). Likamano pakeng tsa Smell Identification le Libaka tsa Neuropsychological: Sephetho se Tsoang ho Mohlala oa Batho ba Moholo-Moahi ba Susumelitsoeng ka Dementia. Journal of Clinical and Experimental Neuropsychology , maq. 11.
Laryngoscope. Buka ea 122, Sengoliloeng sa 7, maqephe a 1455-1465, July 2012. Ho hlahloba ka mokhoa o hlakileng oa ho tseba hore na ho na le tšebetso efe ea ho ntlafatsa ts'oaetso ea Alzheimer's Alzheimer's. http://onlinelibrary.wiley.com/doi/10.1002/lary.23365/abstract.
Setsi sa Sechaba sa ho tsofala. Tsoelo-pele ho Fumana Maloetse a Alzheimer. http://www.nia.nih.gov/alzheimers/publication/2011-2012-alzheimers-disease-progress-report/advances-detecting-alzheimers#.UnJOohAhGoY
> Reijs, B., Ramakers, I. Elias-Sonnenschein, L., Teunissen, C., Koel-Simmelink, et al (2017). Tlhaloso ea Bobebe Tlhaloso le Mafu a Alzheimer Markers ka Cerebrospinal Fluid le Cognition. Journal ea Maloetse a Alzheimer , 60 (3), maq. 10-10-1034.
> Tonacci, A., Bruno, R., Ghiadoni, L., Pratali, L., Berardi, N., et al (2017). Tlhahlobo e hlakileng ka bofokoli bo bonolo ba ho nahanisisa: Correlation le Neurocognitive Tshebetso le Endothelial Mosebetsi. Europe Journal of Neuroscience , 45 (10), pp.1279-1288.
Phetolelo ea Psychiatry. 2012 May, 2 (5), e118. Khetho e khetholloang e bolela ho fokotseha ha tsebo ho batho ba baholo. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365262/.