Na e sa le monyenyane haholo bakeng sa liphatsa tsa lefutso tsa motho ka bomong ho susumetsa liqeto tsa bophelo?
Ha re ntse re ithuta ka ho eketsehileng mabapi le hore na liphatsa tsa rona tsa lefutso li ama bophelo ba rona joang, ho ntse ho hlaka hore lijo li ama motho ka mong ka litsela tse sa tšoaneng. Sena ke sepheo sa tšimo e hlahelang e bitsoang nutrigenomics: ho ithuta kamoo phepo e nepahetseng e re amang kateng liphatseng tsa lefutso, le hore na likhetho tsa rona tsa lijo li ka fetola tsela eo liphatsa tsa rona tsa lefutso li sebetsang ka eona.
Ho ea ka batšehetsi ba limatlafatsi, saense ena e ka bula tsela ea ho iketsetsa motho ka mong-le hore e atlehe haholo-keletso ea hore na u ka ja joang le hore na u ka ja eng.
Ho finyella seo, tlhahlobo ea liphatsa tsa lefutso e ka etsa hore ka letsatsi le leng lijo tse ka u thusang ho finyella ho laola boima ba 'mele le tšireletso e kholo khahlanong le maloetse a sa foleng a kang lefu la pelo , lefu la tsoekere le kankere.
Bophelo bo Botle ba Nutrigenomics
Re leboha karolo ea lipatlisiso tse ntseng li tsoela pele tsa lipatlisiso tsa limatlafatsi, hona joale rea utloisisa hore mefuta e fapaneng ea liphatsa tsa rona tsa liphatsa tsa lefutso e phetha karolo ea lintho tse kang takatso ea lijo, metabolism, karabo ea tsoekere ea mali le ho thehoa ha lisele tse mafura. Ka lebaka la ho fapana ha liphatsa tsa lefutso, keletso e tloaelehileng ea lijo e ka 'na ea tsoela pele ho re thusa ho boloka bophelo bo botle le ho laola boima ba rona.
Ha e le hantle, ho nahanoa hore ho haelloa ke keletso e fapaneng le ea ho ja lijo tse fapaneng ho ka etsa hore re tsoele pele ho hlōleha ho sebetsana le litaba tse kang seoa sa botenya. Ka ho fetola litlhahiso tsa mefuta e le 'ngoe-ka mefuta eohle ea liphatsa tsa phepo e nepahetseng, baeletsi ba fana ka maikutlo a hore batho ba ka' na ba khona ho khomarela keletso eo 'me ba fumane bophelo bo botle ba nako e telele.
The Science Behind Nutrigenomics
Ka nako ena, ho na le ho haelloa ke liphuputso tse kholo, tse telele tse shebileng katleho ea keletso ea lijo tse thehiloeng ho limatlafatsi. Leha ho le joalo, lipatlisiso tse ntseng li hōla li bontša hore lijo tsa lefutso tsa motho ka mong li ka ntlafatsa bophelo ba hao.
Patlisiso ena e kenyelletsa thuto e hatisitsoeng koranteng ea Cell ka 2015, e fumanoeng hore phepo e nepahetseng ea motho ka mong e ka thusa ka ho laola tsoekere ea mali (ntho e ka sehloohong ho thibela le ho laola lefu la tsoekere).
Bakeng sa thuto ena, bafuputsi ba ile ba qala ka ho bokella boitsebiso ba batho ba 800 ka nako ea beke. Boitsebiso bo ne bo bokelloa ka mekhoa e sa tšoaneng, ho kenyeletsoa ts'ebetso ea tsoekere ea mali, liteko tsa mali, lipotso tsa bophelo bo botle, le boitsebiso bo ipolelang boitsebiso ka lijo. Ha ho hlahlojoa lintlha tsena, bafuputsi ba fumane hore litho tse fapaneng tsa thuto li bontšitse likarabo tsa tsoekere tse fapaneng tsa mali lijong tse tšoanang (le hore likarabo tsena ka bomong li lula li tsitsitse letsatsi le leng le le leng).
E le mohlala oa seo ba se fumaneng ka liphello tsa batho ba bang, libuka tseo li bua ka thuto ea batho ba lilemo li bohareng ba kenang botenya le lefu la tsoekere. Ha morupeluoa enoa a ne a kenyeletse litamati ka ho ja ha hae e le karolo ea boiteko ba hae ba ho ja lijo tse phetseng hantle, liteko tse ileng tsa etsoa nakong ea thuto li bontšitse hore tomate e hlile e etsa hore tsoekere ea hae e tsoekere.
Hang ha karolo ea pele ea thuto ena e phethiloe, bafuputsi ba ile ba theha algorithm ho bolela esale pele karabo ea tsoekere ea mali "lijo tsa sebele tsa bophelo." Ka mor'a moo, sehlopha sa lipatlisiso se behile barupeluoa ba bang ba 26 ba ithutoang lijong tse tloaelehileng, tsa liphatsa tsa lefutso. Liphello li senoletse hore ho latela keletso ena ea lijo tsa motho ka mong ho thusitse ho fokotsa lebelo la tsoekere ea mali ka mor'a lijo.
Hape ho na le bopaki bo bong ba hore litlhahiso tsa lijo tsa lefutso li ka ntlafatsa mekhoa ea ho ja, ha li bapisoa le mefuta e mengata ea lijo tse tloaelehileng. Phuputsong e phatlalalitsoeng koranteng ea PLoS One ka 2014, ka mohlala, bafuputsi ba ile ba fa bana ba 138 ba phetseng hantle bophelo bo botle ho lihlopha tse peli tsa thuto: e 'ngoe e fumanoeng keletso ea lijo tse fanoeng ka DNA bakeng sa lijo tse' nè tse fapaneng (lijo tsa caffeine, sodium, vithamine C le tsoekere), le e fumanoang keletso e tloaelehileng ea lijo bakeng sa likarolo tse tšoanang.
Ka mor'a likhoeli tse tharo, keletso e fanoeng ka DNA e thehiloeng ho lijo e ile ea qala ho bonahatsa liphetoho tsa lijo tsa bona.
Ka mor'a likhoeli tse 12, ntlafatso eo e bile ea bohlokoa le ho feta. Ka mohlala, barupeluoa ba tsebang hore ba na le phetoho ea liphatsa tsa lefutso tse amanang le letsoai le khatello e phahameng ea mali ba fokotsa ho ja ha bona hamonate, ha ba bapisoa le ba amohetseng keletso e tloaelehileng bakeng sa ho ja sodium.
Ho phaella moo, phuputso e phatlalalitsoeng ho American Journal of Clinical Nutrition ka 2017 e fumane hore phepo e nepahetseng ea liphatsa tsa lefutso e ka thusa ho ntlafatsa boima ba 'mele ka ho lebisa tlhokomelo ho litšobotsi tsa lefutso tse amanang le botenya.
Li-nutrigenomics le Nutrition ea Botho
Lilemong tsa morao tjena, lik'hamphani tse 'maloa li qalile ho fana ka tlhabollo ea motsoako ka bomong ho itšetlehile ka liteko tsa liphatsa tsa lefutso. Leha ho le joalo, litsebi lefapheng la limatlafatsi li lemosa hore likeletso tse joalo li ka 'na tsa se ke tsa utloahala ka saense. Hobane likamano pakeng tsa limatlafatsi le liphatsa tsa lefutso li rarahane haholo, ho hlokahala lipatlisiso tse ngata ho utloisisa hore na nutrigenomics e ka u thusa joang ho haha lijo tse molemo.
> Mehloli:
> San-Cristobal R, Fallaize R, Macready AL, le al. "Na keletso ea liphatsa tsa lefutso e ka u thusa ho theola 'mele? Lintho tse fumanoang tlhahlobisong ea Food4Me ea European controlled randomised. "Am J Clinical Nutritional. 2017 May; 105 (5): 1204-1213.
> Nielsen DE, El-Sohemy A. "Phatlalatso ea boitsebiso ba liphatsa tsa lefutso le phetoho ea ho ja lijo: teko e laoloang ka nako e telele." PLoS One. 2014 Nov 14; 9 (11): e112665.
> Zeevi D, Korem T, Zmora N, et al. "Ho ja lijo tse nang le boithati ka ho boleloa ha likarabo tsa Glycemic." Cell. 2015 Nov 19; 163 (5): 1079-1094.
> Boikarabello: Boitsebiso bo boletsoeng setšeng sena bo reretsoe merero ea thuto feela 'me ha bo nkele sebaka keletso, ho hlahlojoa kapa kalafo ke ngaka e nang le tumello. Ha e reretsoe ho koahela mekhoa eohle ea tlhokomelo, likamano tsa lithethefatsi, maemo kapa liphello tse bohloko. U lokela ho batla thuso ea meriana hang-hang bakeng sa bophelo bo botle le ho buisana le ngaka pele u sebelisa mefuta e meng ea phekolo kapa u etse phetoho tsamaisong ea hau.