Viscosupplement e tsosolosa Matlotlo a Machaba a Kopaneng a Kopaneng
Synvisc (hylan GF 20) ke e tsitsitseng, e mahlahahlaha, e phahameng ea molek'hule ea boima ba metsi e nang le hylan Mokelikeli, Hylan B gel, le metsi a letsoai. Hylan A le Hylan B li tsoa ho hyaluronan (hape e bitsoa sodium hyaluronate) e entsoeng ka likhoho tsa khōhō. Hyaluronan e boetse ke ntho ea tlhaho e fumanoang 'meleng, haholo-holo, ka bongata manonyeletso.
Hyaluronan ea tlhaho ea 'mele e sebetsa e le mokelikeli o ts'oanang le o tšosang o hlokahalang bakeng sa mosebetsi o tloaelehileng oa kopane.
Synvisc ke e 'ngoe ea li-hyaluronate tse sebelisoang kalafo e tsejoang e le viscosupplementation . Ka linako tse ling phekolo e bitsoa phekolo ea moriana o kopanetsoeng, likokoana-hloko tsa hyaluronan, kapa liente tsa hyaluronate.
Litlhahiso tsa Synvisc
Liente tsa synvisc li amoheloa bakeng sa ho phekoloa bohloko ho bakuli ba nang le lefu la masapo la kneele ba hlōlehileng ho arabela kalafo e ikemiselitseng ho feta, e kang litlhaselo tse se nang lithethefatsi kapa likhetho tse seng tsa lithethefatsi. Ho lefu la masapo a mabeli, ho ka 'na ha e-ba le palo e sa lekaneng ea hyaluronan kapa boleng ba hyaluronan bo ka fokotseha. Tšebeliso ea Synvisc bakeng sa manonyeletso a mang e ntse e phenyekolloa, empa ha e e-s'o amohelehe.
Synvisc e kenngoa, e sebelisa sering e nang le 2 ml, ka ho toba ka mangole ho tsosolosa thepa ea ho thibela le ho hlahisa metsi a tloaelehileng a motsoako.
Ho na le sehlahisoa se seng sa Synvisc, se tsejoang e le Synvisc-One, se tsamaisoang e le injection e le ngoe (nako e le 'ngoe) intra-articular (6 ml).
Li-Synvisc Injections - Tlhaloso
- Lisebelisuoa tsa boipheliso li 'nile tsa ithutoa bakeng sa phekolo ea mafu a masapo ho tloha lilemong tsa bo-1970.
- Synvisc e ne e amoheloa ke FDA ka 08/08/97.
- Liente tsa synvisc hangata li fanoa e le letoto la liente tse tharo, hanngoe ka beke, beke e le 'ngoe e arohane. Synvisc-One e ntshetswa pele e le injection ea nako e le 'ngoe, e le sebaka se fapaneng le lihlopha tse tharo tse nang le Synvisc.
- E le hore u fumane liphello tse ntle, osteoarthritic synovial fluid e atisa ho tlosoa ka lengole pele ho ente ea pele.
- Synvisc e nkoa e le phekolo kapa phekolo, eseng lithethefatsi.
Litla-morao le Likotsi
Litla-morao tse tloaelehileng tse amanang le liente tsa Synvisc li kenyeletsa bohloko bootong bo kenngoeng, ho ruruha ka lengole le kenyelitsoeng . Liketsahalo tse ling tse bohloko tse ka 'nang tsa e-ba teng ka liente tsa intra-articular li kenyeletsa arthralgia (bohloko bo kopantsoeng), ho khomarela ho kopantsoeng, ho tsuba ho kopantsoeng, mofuthu o kopantsoeng , mofuthu sebakeng se entsoeng ka ente, ramatiki, ramatiki le ho se tloaelehe.
Ho hlahloba kamora 'marang-rang oa 3-injection ea Synvisc e senola tse ling tse sa tloaelehang tsa tsamaiso tse kenyelletsang ho akarelletsa lehare, maqhubu, feberu, ho nyekeloa ke hlooho, hlooho ea mokokotlo, moferefere, likhahla, mesifa ea matšoafo, malaise , ho phefumoloha ha edema, le ka seoelo, thrombocytopenia ).
Li-contraindications le Litemoso
Synvisc ha ea lokela ho kenngoa ho bakuli ba nang le hypersensitivity tse tsebahalang ho lihlahisoa tsa hyaluronan. Hape, Synvisc ha ea lokela ho kenngoa ka mangole ka tšoaetso e kopanetsoeng, maloetse a letlalo kapa mafu a tšoaetsanoang, kapa tšoaetso sebakeng seo ho potolohileng sebaka sa ente.
Synvisc e lokela ho sebelisoa feela e le injection ea intra-articular (ka hare ho kopane).
Haeba e kenngoa ka ntle ho motsoako ka mahlaseli a synovial kapa capsule e kopane, liketsahalo tse mpe tsa sebakeng seo kapa tsa tsamaiso li ka etsahala. Injection e entsoeng ka methapo ea Synvisc (ka har'a sejana sa mali) e ka baka liketsahalo tse mpe tsa tsamaiso 'me li lokela ho qojoa.
Kamora 'meleng oa Synvisc, ho kgothaletswa hore bakuli ba lokela ho qoba mesebetsi e boima kapa mesebetsi e telele ea ho jara boima bakeng sa lihora tse 48. Buisanang ka litlhahiso tse tobileng tse amanang le boemo ba hau ka boeena le ngaka ea hau.
Tšireletseho le katleho ea Synvisc ho basali ba nang le bakhachane kapa basali ba hlokomelang ha e e-s'o thehoe.
Haeba u e-na le menoana ea masiba, mahe, likhoho kapa lihlahisoa tse ling tse tsoang linonyana - tsebisa ngaka ea hau.
Ho bapisa Synvisc ho Corticosteroid Injections
Synvisc e bapisoa le katleho ho entra-articular corticosteroid e entsoeng ka potlako empa e khutšoanyane ho feta Synvisc. Lijoana tse phetoang tsa synvisc li nkoa li sireletsehile ho feta corticosteroids ho bakuli ba nang le li-comorbidities tse ka etsang hore corticosteroids e hanyetsane. Hape hoa lokela ho hlokomeloa hore tšebeliso ea NSAID e ka fokotsa bakuli ba bang ba latelang li-injection tsa Synvisc.
Lisebelisoa:
Tlhaloso ea Mokuli Synvisc, Sanofi US.
http://products.sanofi.us/synvisc/synvisc.html
Information Patients Synvisc-One. Sanofi US.
http://products.sanofi.us/synviscone/synviscone.html
Hylan GF 20: Tlhahlobo ea ts'ireletseho ea eona le ts'ebetso ea Ts'ebetso ea Palo e Kopaneng ea Osteoarthritis. Magliore A. et al. Clinical Medical Insights: Mathata a Musculoskeletal Arthritis. 2010; 3: 55-68.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998981/