HPA axis ke tlhaloso ea motsoako oa hypothalamic-pituitary-adrenal. E hlalosa mokhoa o rarahaneng oa likamano pakeng tsa likarolo tse peli tsa boko-hypothalamus le sekhahla sa pituitary-le litšoelesa tsa adrenal kapa suprarenal tse ka holimo ho liphio.
The axis ea HPA ke karolo e kholo ea tsamaiso e laolang tsela eo u arabelang ka eona khatellong ea maikutlo, khatello ea kelello le kotsi.
E boetse e thusa ho laola lintho tse ling tse ngata 'meleng oa hau, tse kang mocheso oa hau, ts'ebetso ea mali, tsamaiso ea' mele ea ho itšireletsa mafung, maikutlo, ho kopanela liphate le tšebeliso ea matla.
Ho fanoa ka lethathamo la mesebetsi, le ho bapisa le lethathamo le tsejoang la matšoao le matšoao a fibromyalgia le boloetse bo sa foleng ba mokhathala , ha ho makatse hore ebe lipatlisiso li amahanya maemo ana le maemo a sa tloaelehang a li-HPA.
HPA Axis le Boikarabello ba Ts'ebetsong ea Sensitivity Syndromes
Ha e le hantle, lipatlisiso tse ling li bontša hore axisisi ea HPA e phetha karolo ea syndromes eohle ea kutloisiso , malapa a mafu a fibolloyalgia, boloetse bo sa foleng ba mokhathala, le maemo a mang a mangata ao ho lumeloa hore a le ho 'ona. Maloetse ana kaofela a amahanngoa le hyper-sensitivity ea tsamaiso ea methapo ea bohareng (boko le mokokotlo oa mokokotlo.)
Karolo ea sekhahla sa HPA ha ho e-s'o utloisisoe hantle, empa ho fihlela joale, lipatlisiso li fana ka maikutlo a hore li phetha karolo ea bohlokoa. Liphuputso li fana ka maikutlo:
- Ho fokotsa mosebetsi oa HPA-axis o lebisa karolong e fokolang ea phepelo ea cortisol khatellong ea khatello ea kelello e sa foleng
- Re-cortisol e tlase e tlamisoa ke matšoao a maholo a ho kula a bakoang ke mokhathala ( Kempke)
- Matšoenyeho a bana a ka 'na a lebisa tlhokomelong ea HPA-axis, e ka tlatsetsang ho nts'etsopele ea maemo ana
- Koetliso e bonolo ea kamehla, e kang ho otlolla , e ka ntlafatsa mosebetsi oa HPA-axis ka fibromyalgia
- Ho se sebetse ha HPA-axia ho ka senya mosebetsi oa fascia (marang-rang a pharaletseng ea lik'hemik'hale tse sebetsang) ho fibromyalgia
Bafuputsi ba bang ba 'nile ba batla mekhoa e mecha ea ho phekola e lebisang molekeng oa HPA o sa sebetseng ka maemo ana.
H axis ea HPA e boetse e ameha holellong ea khatello ea kelello , lefu la ho ferekana kelellong, lefu la post-traumatic stress, ho tepella maikutlong, ho tetebela maikutlo le ho halefisoa ke bowel syndrome .
Mohloli:
Borsini A, et al. Meriana ea kelello. 2014 Jul; 44 (9): 1809-23. Matšoenyeho a bana ho nts'etsopele ea mokhathala oa syndromes: tlhahlobo ea lilemong tse 20 tse fetileng tsa lipatlisiso.
Genc A. Journal ea saense ea phekolo ea 'mele. 2015 Jul; 27 (7): 2225-31. Na boikoetliso bo sebetsang bo ama tsela ea hypothalamic-pituitary-adrenal response ho bakuli ba nang le lefu la fibromyalgia?
Monyenyane RH, Schweinhardt P. Hona joale rheumatology e hlahloba. 2015; 11 (2): 116-30. Matšoao a hlophisitsoeng: liphello tse fapaneng tse kopantsoeng ka morero.
Kempke S, et al. Bophelo bo botle ba kelello. 2015 Tlhahiso ea 21. [Epub pele ho khatiso] Ho ipeha boemong bo botle ba ho iketsetsa letho ho bolela esale pele hore karabo e tlase e fokotsa khatello ea liteko ho bakuli ba nang le boloetse bo sa feleng ba mokhathala.
Liptan GL. Journal ea bodywork le ho tsamaisa phekolo. 2010 Jan; 14 (1): 3-12. Fascia: Ho haelloa ke letho ho utloisiseng ha rona ka boloetse ba fibromyalgia.
Tomas C, Newton J, Watson S. ISRN kelello ea maikutlo. 2013 Sep 30; 2013: 784520. Ho hlahloba ts'ebetsong ea hypothalamic-pituitary-adrenal axis ka boloetse bo sa feleng ba mokhathala.