Ho hōla ha li-hormone ea batho ho na le mesebetsi e mengata 'meleng,' me ho ba le bofokoli ba eona ho ka lebisa k'holong e ngata ea k'holeseterole le e phahameng ea LDL ea k'holeseterole. Synthetic HGH e hlekefetsoang ke baatlelete ba se na mathata a ka ba bothata.
Hormone ea ho hōla ha batho e ama maemo a k'holeseterole joang?
Ho hōla ha motho (HGH kapa GH) ke k'hemik'hale e hlahisoang ke lesela la pituitary bokong ba hao.
HGH e susumetsa lesapo la bone nakong ea bongoaneng, ho lumella bana hore ba hōle ho fihlela boemong bo tloaelehileng ba batho ba baholo. Ho phaella moo, e thusa 'mele ho senya limolek'hule tse ngata tsa lipid le ho li tlosa maling hammoho le triglycerides.
HGH e boetse e phetha karolo ea ho matlafatsa tlhahiso ea liprotheine, ho thibela insulin maling le ho thusa 'mele hore o boloke electrolyte, ho akarelletsa phosphate, sodium le metsi.
Bothata ba HGH
'Mele oa hau o hlahisa HGH bophelong bohle ba hau ho tloha pele o tsoaloa le ho fihla litekong tsa tlhōrō ho pholletsa le bokhachane. HGH tlhahiso e fokotseha hanyane ka hanyane hohle ha motho e moholo. Ka nako e 'ngoe litšoeliso tsa mokokotlo oa pituitary' me 'mele ha o hlahise ho lekana ha hormone ena. Haeba sena se etsahala bongoaneng, khōlo e tloaelehileng e ka ama. Ha motho a se a le moholo, phello e tloaelehileng e fetotsoe 'meleng oa' mele, o na le mafura a mangata a 'mele le mesifa ea boima bo sa thekeseleng. Bakeng sa batho ba baholo, sesosa se ka sehloohong sa maemo a tlase a HGH ke sesepa se entsoeng ka letsoalo la pituitary.
Ho buuoa ke bokooa ho ka boela ha senya tlhahiso ea HGH.
HGH ho haelloa ke batho ba baholo ke ntho e sa tloaelehang haholo. Phuputso ea 1999 e neng e lebisitse tlhokomelo ho HGH ea Fora e ile ea etsa qeto ea hore batho ba 12 ho ba milione ba baholo (0.0012%) ba na le bothata bona. Har'a bana, ho haelloa ke joalo ho tloaelehile haholo, empa ho ntse ho tloaelehile haholo, ho etsahala ho bana ba ka bang 2 000 ho ba 100 000 (0.0024%).
HGH e tlaase hakae ha e ama cholesterol
Ntle le ho phahamisa maemo a mafura a bolokiloeng 'meleng le ho theola mahlaseli a boima a' mele, maemong a tlase a HGH a boetse a lebisa holellong e ngata ea k'holeseterole, lefu la pelo, ho ba le masapo a fokolang a masapo, ho fetoloa kelellong le kotsing e kholo ea ho shoa ka kakaretso.
Ho phaella liphetohong tsa mafura le boima ba 'mele, batho ba nang le bokooa ba HGH ba sa tšoaroeng ba na le "li-cholesterol tse mpe" ( LDL ) tse bapisoang le batho ba bang kaofela. Mofuta ona oa k'holeseterole o atisa ho khomarela marako a artery, ho etsa li-plaque tse hlahisang mofuta oa lefu la pelo le tsejoang e le atherosclerosis . Li-plaque tsa atherosclerotic li ka senyeha, li etsa hore mali a khaotse 'me a ka thibela ho phalla ha mali ho ea pelong kapa boko, bo bakang lefu la pelo kapa stroke.
Liphello tsa HGH Ts'oaetso ka Cholesterol
HGH e ka nkeloa sebaka ke li-injections tsa li-hormone tse hōlileng tsa tlhaho tse tsejoang e le li-hormone tse eketsehileng tsa motho (rHGH). Liente tsena li fumanoe ho susumelletsa bana ho hōla, ho eketsa boima ba mesifa le bana ba baholo, le ho ntlafatsa mabaka a mang a amehang ke maemo a tlaase a HGH.
Ka lebaka la ho khona ho matlafatsa mesifa ea 'mele, ka linako tse ling RHGH e' nile ea hlekefetsoa ke baatlelete le ba bang ba batlang ho fetola ponahalo ea bona le ho ntlafatsa katleho ea lipapali.
Ka bomalimabe, kaha mofuta ona oa tšebeliso o atisa ho ipata, lingaka le bo-rasaense ha ba na boitsebiso bo bongata mabapi le liphello tse ntle kapa tse mpe, ho kenyelletsa le phello ea k'holeseterole le kotsi ea pelo ea rHGH ho sebelisoa ke batho ba nang le maemo a tloaelehileng a HGH.
Lipatlisiso ka phello ea rHGH ka k'holeseterole e tsoakane. Liphuputso tse ling li hlokometse hore hormone ea maiketsetso ha e fetole maemo a k'holeseterole, ha ba bang ba bontšitse letšoao la "li-cholesterol tse mpe". Phuputso e 'ngoe e bontšitse hore ho na le letšoao la "k'holeseterole e mpe" le li-k'holeseterole ka ho feletseng likhoeling tse tharo tse qalang, empa ka mor'a moo ho sa tsotellehe ts'ebetsong ea barupeluoa ba li-cholesterol ba sebelisang rHGH ba ile ba khutlela moo ba neng ba le teng pele ba qala li-injection tsa hormone.
Liphuputso tse ling li tlalehile liphello tse mpe tsa tšebeliso ea rHGH, ho akarelletsa le maemo a phahameng a lipoprotein (a) . Joaloka "k'holeseterole e mpe," litekanyetso tse phahameng tsa lipoprotein (a) li tlatsetsa libakeng tsa atherosclerotic ka marako a methapo. Leha ho le joalo, lipatlisiso li boetse li fana ka maikutlo a hore rHGH e fokotsa menyetla ea mali ea C-reactive protein (CRP), mme ho fokotseha maemo a CRP ho bonahala e le pontšo ea ho fokotsa kotsi ea mathata a pelo.
Batho ba nkang rHGH ba lokela ho etsa joalo feela joalokaha ba laetsoe ke ngaka kapa mooki. Hape ba lokela ho netefatsa hore ba boloka litekanyetso tsa bona tsa k'holeseterole hobane maemo a tlase a HGH a ka eketsa boholo ba k'holeseterole. Batho ba bang ba nkang rHGH ba ka boela ba hloka meriana e theolelang ea k'holeseterole, e kang statin, ho theola likarolo tsa k'holeseterole le ho fokotsa kotsi ea ho ba le lefu la pelo kapa stroke.
Ba sebelisang rHGH ntle le keletso ea mofani oa litšebeletso tsa bophelo bo botle ba lefapha la bophelo ba lokela ho hlokomela hore hormone ena e ka ba le liphello tse bohlokoa (le tse ka bang kotsi) lihlopheng tsa k'holeseterole le bophelo bo botle ba pelo. Le hoja phekolo ea RHGH e ka ruisa batho ba nang le maemo a tlase a tlhaho a HGH, litsebi ha li tsebe liphello tsa pelo kapa metsoako ea RHGH e sebelisoang ho ba nang le maemo a tloaelehileng a HGH.
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