Hangata k'holeseterole e phahameng ha e bake matšoao leha e le afe a sa phutholohang, kahoo ho ka 'na ha e-ba boima ho iphapanyetsa. Leha ho le joalo, karolo e phahameng ea k'holeseterole maling e ka lebisa ho hlasetsoeng ke pelo, ho otloa ke lefu, ho thibela methapo ea mali maotong le liphio, 'me e ka ba ea tlatsetsa ho dementia. Ka lehlohonolo, ho ja, ho ikoetlisa le ho noa meriana ho thusa ho fokotsa li-cholesterol le ho fokotsa kotsi ea mathata a mang a tebileng a bophelo bo botle.
High Cholesterol le Mafu a Pelo
Liphuputso tse kholo li bontšitse hore batho ba nang le k'holeseterole e phahameng ba na le kotsi e kholo ea ho ba le lefu la pelo ho feta batho ba nang le k'holeseterole e tloaelehileng. Ka mohlala, karolo ea 250 ea k'holeseterole e atisa ho ba le menyetla ea ho hlaolela mafu a pelo, athe boemo ba 300 bo eketsa kotsi ka ho hlano. Ho feta moo, batho ba nang le k'holeseterole e phahameng-e nang le boloetse ba pelo -kapa ba se nang lefu la pelo -ba ka ba le monyetla oa ho shoa ka lebaka la lefu la pelo ho feta makhetlo a 4,5 ho feta ba nang le k'holeseterole ka tlaase ho 200.
Cholesterol ke ntho e tsitsitseng, e nang le bokahohle e potolohang maling, 'me e na le mefuta e' meli e fapaneng ea k'holeseterole. "Cholesterol e mpe," kapa LDL , e phahamisa kotsi ea lefu la pelo. LDL ke seo ho buuoang ka sona ha sepheo ke ho theola k'holeseterole. "Cholesterol e ntle," kapa HDL, ke mofuta o hlileng o thusang ho sireletsa mafu a pelo. Litekanyetso tse phahameng tsa HDL li molemo.
LDL, ka lehlakoreng le leng, e atisa ho khomarela marako a methapo ea mali ho etsa li-plaque tse sitisang phekolo ea mali e tloaelehileng. Li-plaque li ka boela tsa tloha lijaneng tse kholo tsa mali le ho tsamaea ka mali ho fihlela li koala ka ho feletseng sejana se senyenyane, se ka bakang lefu la pelo. Ka lehlohonolo, k'holeseterole-ho theola meriana e kang li-statine e ka fokotsa ka matla haholo monyetla oa lefu la pelo.
Lipitor (atorvastatin), Zocor (simvastatin) le Crestor (rosuvastatin) ke mehlala ea li-statins tse tloaelehileng.
High Cholesterol le Stroke
Feela joalokaha likarolo li ka thibela mali ho tsoa ha methapo ea pelo e bakang lefu la pelo, ntho eo e ka 'na ea boela ea khomarela methapo ea pelo e tsoang pakeng tsa pelo le boko. Ha karoloana ea letheka e theoha ho tswa ho araro ea carotid, e ka ea boong ho baka "tlhaselo ea boko" kapa stroke. Le hoja meriana e ngata ea ho theola k'holeseterole e fokotsa kotsi ea lefu la pelo, li-statin li ka boela tsa thibela liropo.
High Cholesterol le Dementia
Ho na le bopaki bo bongata bo bontšang hore k'holeseterole e phahameng le lijo tse ngata tse mafura le mafura a mangata li ka boela tsa tlatsetsa ho dementia , ho kenyelletsa le 'dementia' e bakiloeng ke lefu la Alzheimer's . Li-autopsies tsa bakuli ba neng ba e-na le lefu la Alzheimer, ba neng ba boetse ba tšoeroe ke lefu la 'dementia', ba ile ba bontša methapo ea meriana e thibelang haholo e tšoanang le methapo ea methapo ea pelo e tsejoang e bakiloe ke k'holeseterole e phahameng. Leha ho le joalo, liphuputso tse ling li bontša hore ho nka li-statins ho ka thusa ho thibela 'dementia' 'me mohlomong ho liehisa tsoelo-pele ea' dementia 'e amanang le lefu la Alzheimer.
Ho Hlokomela Cholesterol ea Hao
Tsela e molemo ka ho fetisisa ea ho boloka k'holeseterole e le ka ho khomarela ho ja lijo tse tlaase .
Haholo-holo, ke habohlokoa ho qoba mafura a mangata, ao e leng mafura a tsoang liphoofolong tse kang botoro kapa bohobe, hobane mafura a mangata a tlatsetsa haholo k'holong ea k'holeseterole e phahameng le ho "maemo a phahameng a k'holeseterole e mpe" kapa LDL. Ha lijo tse nang le phepo e nepahetseng li fetoha, ho ka khoneha ho fokotsa li-cholesterol maemong a tloaelehileng, a ka etsang hore bakuli ba khone ho buisana le bafani ba bona ba tlhokomelo ea bophelo ka ho fokotsa meriana ea bona ea k'holeseterole.
Ho ka ba thata ho fetola lilemo tsa mekhoa ea ho ja. Ho e-na le ho ja lijo tse feletseng, u ka fetola lijo tsa hau hanyane ka hanyane, ua fokotsa tsela eo u phelang ka eona bophelo bo botle.
Ka mohlala:
- Qoba lijo tse halikiloeng. Ho e-na le hoo, khetha lintho tse entsoeng, tse halikiloeng, tse koahetsoeng kapa tse chekiloeng.
- Kopa lisoso ka lehlakore.
- Etsa meroho karolo e kholo ea lijo tsa hau, eseng nama.
- Khetha mefuta e fokolang ea mafura, joalo ka litlhapi, likhoho (ka letlalo le tlosoa) kapa ho khaola ho matla ha lijo tse khubelu.
- Sebelisa linoko bakeng sa tatso, ho e-na le botoro kapa oli.
Tsela e molemo ka ho fetisisa ea ho ntlafatsa HDL ke ka ho ikoetlisa , ho tsamaea, ho tsamaea, ho palama libaesekele, ho sesa, ho ba aerobic kapa ho tsamaea maoto. Haeba ho ikoetlisa ho le ncha ho mokhoa oo u phelang ka oona, ho ka 'na ha hlokahala hore u leke lithupelo tse sa tšoaneng pele u fumana moralo o sebetsang ho uena. Batho ba bang ba rata ho ikoetlisa lapeng, athe ba bang ba rata ho ikoetlisa. Batho ba bang ba ikoetlisa hoseng 'me ba bang ba khetha ho ikoetlisa hamorao mantsiboea.
Haeba mofani oa hao oa tlhokomelo ea bophelo a khetha ho fana ka lithethefatsi tse theohelang k'holeseterole, netefatsa hore o fana ka tlhahisoleseding e mabapi le meriana leha e le efe eo u ka e nkang. Hape etsa bonnete ba hore o noa meriana joalokaha o laetsoe. Ka linako tse ling lithethefatsi tsena li ka baka litla-morao tse sa thabiseng, tse kang ho nyekeloa ke pelo, bohloko ba mpeng, kapa mesifa ea mesifa. Bua ka litla-morao leha e le life tseo u li utloang ho mofani oa tlhokomelo ea bophelo hang-hang. Maemong a mangata, o ka nka mehato ea ho fokotsa matšoao kapa ho fetola meriana e fapaneng.
Lisebelisoa:
Bernick, C., le al. "Litemana le Mosebetsi oa ho Tseba Tsebo ho Batho ba Hōlileng." Neurology 65 (2005): 1388-94.
Furie, Karen L., Janet L. Wilterdink, le J. Philip Kistler. "Thibelo ea Sekhahla ea Stroke: Ntho ea Likotsi ea ho Fokotsa" UpToDate.com . 2008. UpToDate.
Maase, I. Border, D. Ho phaella moo, A. Al Khedr, F. Richard, C. Libersa le F. Pasquier. "Mesebetsi e ka tlaase ea Lipid E amana le ho Fokotseha ha Nakoana ka Tsela ea Mafu a Alzheimer." Journal of Neurology, Neurosurgery le Psychiatry 76 (2005): 1624-9.
Pekannen, J., S. Linn, G. Heiss, et al. NEJM "Ho shoa ha Lilemo Tse leshome ho Ts'oaetso ea Lefu ho Amanang le Cholesterol Lenane la Har'a Batho ba nang le Lefu la Matšoao la Mafu le le se nang Pelisi." New England Journal of Medicine 332 (1990): 1700-7.
Tlhōlisano, Daniel le Michael Alexander. "Thibelo ea Dementia." UpToDate.com . 2008. UpToDate.
Rosenson, Robert S. "Litlhahlobo tsa Mokuli oa Cholesterol Tse Fokolang Khanyetso ea Mantlha ea Mafu a Pelo ea Coronary." UpToDate.com . 2008. UpToDate.
Rosenson, Robert S. "Litlhahlobo tsa Mokuli oa Cholesterol ho Fokotsa Bakuli ba nang le Maloetse a Pelo ea Coronary kapa Coronary Risk Equivalents." UpToDate.com . 2008. UpToDate.
Shadlen, Marie-Florence, le Eric B. Larson. "Lintho Tse Kotsing tsa Dementia." UpToDate.com . 2008. UpToDate.
J. Stamler, D. Wentworth, le JD Neaton. "Na ho na le Kamano pakeng tsa Seromone ea Cholesterol le Kotsi ea Pele ho Lefu Lefu le tsoang ho Coronary Heart Heart Continuous and Graded? Lintho tse fumanoang ka 345,222 Lits'oants'o tsa Mantlha tsa Tlhahlobo ea Likotsi Tse Ngata (MRFIT) Journal of the American Medical Association 256 (1986): 2823-8.
Wilson, Peter WF. "Tlhahlobo ea Likotsi Tsa Likotsi Tsa Mafu a Mafu." UpToDate.com . 2008. UpToDate.
Wolozin, Benjamin, Wendy Kellman, Paul Ruosseau, Gastone G. Gelesia le George Siegel. "Ho ata ho fokolang ha Mafu a Alzheimer a Amanang le 3-Hydroxy-3-Methylglutaryl Coenzyme A Inhibitors." Libuka tsa Neurology 57 (2000): 1439-43.
Wright, Clinton B. "Etiology, Lipontšo tsa Bophelo, le ho Hlahloba ka Vascular Dementia." UpToDate.com . 2008. UpToDate.
" Tataiso ea Hao ea ho Fokotsa Cholesterol ea Hao ka TLC ." Mokhatlo oa Sechaba oa Thuto ea Cholesterol (NCEP) le NHLBI ea Boima bo Botle ba Thuto ea Thuto . Dec. 2005. National Heart, Lung, le Blood Institute (NHLBI), Mekhatlo ea Sechaba ea Bophelo.