Ka hypothyroidism, qoqotho ea qoqotho e sitoa ho hlahisa homone ea qoqotho thyroxine (eo hape e bitsoang T4). Hobane T4 ke ea bohlokoa ka ho fetisisa ho laola metabolism ea 'mele, ho sebetsa ha lijo, ho sebetsa ha mesifa le mosebetsi oa pelo , hypothyroidism ke bothata bo tebileng kamehla.
Boloetse ba qoqotho ka boeona bo laoloa ke hormone ea TSH (thyroid e susumetsang hormone).
Haeba qoqotho ea qoqotho e sa hlahise T4 e lekaneng, litekanyetso tsa TSH lia eketseha e le ho susumelletsa qoqotho hore e sebetse ka thata. Ka hypothyroidism-eo qoqotho e ke keng ea khona ho etsa T4 e lekaneng-hangata litekanyetso tsa TSH li phahame haholo.
The hypothyroidism e ka tlaase mona ke boemo boo li-T4 li lulang ho lona boemong bo tloaelehileng (ke hore, hyphenroidism e hlakileng ha e teng), empa litekanyetso tsa TSH li phahame: litekanyetso tse phahameng tsa TSH li hlokahalang ho boloka tekanyo ea T4 e tloaelehileng. Kahoo hypothyroidism e tsamaeang ka lihlopha tse nyenyane e bolela hore qoqotho ea qoqotho ha e sebetse ka ho feletseng. Ke feela "ho shapa" qoqotho (e nang le litekanyetso tse phahameng tsa TSH) hore litekanyo tse lekaneng tsa T4 li ka bolokoa.
Kajeno ho na le phehisano e kholo mabapi le bohlokoa ba 'nete ea "subclinical hypothyroidism". Hobane likhaolo tsa T4 ha e le hantle li tloaelehile boemong bona, ka khopolo, litlhaku tse nyenyane tsa hypothyroidism ha lia lokela ho ba bothata bo bongata.
Empa bopaki bo fana ka maikutlo a hore subclinical hypothyroidism e hlahisa mathata a litliniki bonyane ka linako tse ling-kahoo, bonyane maemong a mang, e lokela ho phekoloa.
Mohlomong ntho e kholo ka ho fetisisa ka ho tšoaetsoa ke li-hypothyroidism ke hore e ka ama pelo.
Tsela eo likokoana-hloko tsa Hypothyroidism e Etsoang ka Eona e Ngotsoeng ka Eona
Boemo bona bo fumanoa bo e-na le liteko tsa mali, haholo-holo, ka ho lekanya litekanyetso tsa T4 le litekanyetso tsa TSH.
Litlhapi tsa li-subclinical li teng ha li-T4 li le boemong bo tloaelehileng (0,8 ho ea 1.8 ng / L), 'me litekanyetso tsa TSH li phahametse mefuta e tloaelehileng (0.3 ho 3.04 mU / L). Leha ho le joalo, litsebi tse ngata li nka subclinical hypothyroidism e le "ea bohlokoa" hafeela likhahla tsa TSH li phahame haholo: ka holimo ho 10 mU / L.
Lisosa
Ho lumeloa hore hypothyroidism ea subclinical ke mokhoa o bonolo feela, kapa mofuta oa pele, oa mathata ao ka tloaelo a hlahisang hypothyroidism ka botlalo-haholo-holo autoimmune thyroiditis ( Hashimoto's thyroiditis ). Ha e le hantle, ha nako e ntse e ea, ba bangata halofo ea batho ba nang le subclinical hypothyroidism ba tla tsoela pele ho hlahisa hypothyroidism e hlakileng, e nang le maemo a tlaase a T4 le matšoao ' ohle a tsamaeang le eona . Kahoo, lebaka le le leng la hore lingaka tse ling li sebetsane le li-subclinical hypothyroidism ke ho thibela phetoho e qetellang ea boemo ba 'nete ba hypothyroidism.
Matšoao a ka Khonehang?
Ha ho bonahala eka boemo bona ha bo hlahise matšoao ho batho ba bangata, ba bang ba tla amohela matšoao a bonolo a bontšang hypothyroidism, e kang ho patoa, mokhathala, kapa phaello e sa hlalosoang. Ho boetse ho bolelloa hore batho ba nang le subclinical hypothyroidism ba ka ba le tšusumetso e kholo ea ho tšoenyeha, khatello ea kelello, kapa mathata a ho utloisisa.
Kamoo e Amang Pelo Kateng
Ntle le kotsi ea ho qetela ho hlahisa hypothyroidism e sa utloahaleng, mookameli ea tšoenyehileng ka subclinical hypothyroidism ke hore e amahanngoa le ho eketseha ha lefu la pelo.
Liphuputso tse 'maloa li se li bontšitse kamano pakeng tsa litekanyetso tse phahameng tsa TSH (tse fetang 10 mU / L) le ntshetsopele ea mafu a li-artery (CAD) . Phuputsong e kopanngoeng ea lithuto tse 'maloa tsa bongaka tse kenyeletsang bakuli ba fetang 25,000, hypothyroidism e tsamaeang ka tlas'a lefatše e ne e amahanngoa le ho eketseha ha lefu la pelo, lefu la CAD le lefu la pelo. Phuputso e 'ngoe e kopaneng e fumane kotsing e kholo ea ho hloleha ha pelo ho bakuli ba nang le subclinical hypothyroidism.
'Me lithuto tse' maloa li amahanngoa le hypothyroidism tse nang le lik'hemik'hale tse nang le k'holeseterole e eketsehileng.
Le hoja setsoalle se sa ipaka e le sesosa-le-phello, hoa hlokomeleha hore hangata hypothyroidism e hlahisa maloetse a bohlokoa a pelo. Taba ena e fana ka maikutlo a hore khopolo ea hypothyroidism e ka ba le tšusumetso e mpe pelong. Keketseho ea kotsi ea pelo e bonoang ka subclinical hypothyroidism ke eona tšobotsi e bohloko ka ho fetisisa ea boemo bona.
Na Likokoana-hloko tsa Hypothyroidism li Lokela ho Tšoaroa?
Litlhapi tsa hypothyroidism li ka phekoloa ka ho fana ka phekolo ea lihomone tsa qoqotho. Kalafo e tataisoa ke ho hlahloba ka hloko maemo a mali a TSH; ho na le hormone ea qoqotho e lekaneng ho fokotsa litekanyetso tsa TSH ho khutlela mefuteng e tloaelehileng.
Ho na le bopaki bo fokolang feela bo tsoang lithutong tsa meriana ea ho phekola subclinical hypothyroidism e ntlafatsa matšoao. Liphuputsong tse bontšang hore e fokotsa matšoao, phaello e lekanyang e bonahala e lekanyelitsoe ho bakuli bao maemong a pele a TSH a phahameng haholo (ke hore, ho feta 10 mU / L).
Ka mokhoa o ts'oanang, bopaki ba ho phekola hypothyroidism e fokolang e fokotsa kotsi ea lefu la pelo e boetse e lekanyelitsoe. Phuputsong e entsoeng Great Britain, har'a bakuli ba banyenyane (ba ka tlaase ho lilemo tse 70) le subclinical hypothyroidism, kotsi ea lefu la pelo e latelang e ne e le tlase haholo ho bakuli ba ileng ba fumana phekolo ea lihomone tsa qoqotho. Ha ho na melemo ea kalafo ho bakuli ba hōlileng ba nang le hypothyroidism.
Ho feta moo, ho phekola subclinical hypothyroidism haholo ho ntlafatsa tse 'maloa tsa lefu la pelo, ho akarelletsa le maemo a k'holeseterole, litekanyetso tsa CRP le mosebetsi oa sephahla.
The Bottom Line
Boholo ba litsebi li khothalletsa ho phekola subclinical hypothyroidism ha likhahla tsa TSH li feta 10 mU / L, ho sa tsotellehe hore na matšoao a teng kapa che.
Ebang li-hypothyroidism tse nyenyane li lokela ho phekoloa ha litekanyetso tsa TSH li le tlase ho 10 mU / L e ntse e le taba ea likhohlano. Lingaka tse ngata li khothaletsa kalafo esita le ka lehlakoreng le ka tlaase haeba bakuli ba e-na le matšoao a bontšang hypothyroidism, kapa haeba ba na le maemo a phahameng a k'holeseterole kapa mabaka a mang a kotsi a lefu la pelo.
Na U Lokela ho Lekoa?
Matsatsing a khale (lilemo tse leshome kapa tse peli tse fetileng), tlhahlobo ea ts'ebetso ea qoqotho e ne e le karolo e tloaelehileng ea tlhahlobo ea bongaka. Empa ka thahasello ea litšenyehelo tsa litšenyehelo, hangata ha se sa tloaeleha.
Ke ntho e utloahalang ho botsa ngaka ea hau hore u fumane liteko tsa mali ea qoqotho haeba u e-na le matšoao a bontšang hypothyroidism (bona ka holimo), haeba u phahame ka li-cholesterol, kapa u batla feela ho etsa bonnete ba hore u etsa sohle se matleng a hao ho fokotsa kotsi ea pelo ea hau. .
Lisebelisoa:
Rodondi N, Elzen WP, Bauer DC, le al. Hypotothyroidism ea lihlopha tse nyenyane le kotsi ea lefu la pelo le lefu la pelo. JAMA 2010; 304: 1365.
Gencer B, Collet TH, Virgini V, et al. Tšoaetso ea qoqotho ea likokoana-hloko e kotsing le likotsi tsa ho hloleha ha pelo: ho hlahlojoa ha litlhaloso ho motho e mong ho tloha ho lihlopha tse tšeletseng tse tlang. Tsamaiso ea 2012; 126: 1040.
Razvi S, Weaver JU, Butler TJ, Pearce SH. Levothyroxine Phekolo ea Likokoana-hloko tsa Hypothyroidism, Liketsahalo Tse Bobebe le Tse se Nang Matšoao le Mafu. Arch Intern Med 2012.