Ho nahana ka libaktheria ka lebaka la mafu a tšoaetsanoang le maloetse a itseng ao ba a bakang ho thehiloe ka metso meriana. Ho tswa ho likokoana-hloko tse bakang tšoaetso ea nama kapa likokoana-hloko ho libaktheria tse ikarabellang bakeng sa lintho tse kang methapo ea motsoako, tšoaetso ea sinus le tšoaetso ea moriana, kajeno likokoana-hloko li ntse li le matla a matla a ho baloa.
Joalokaha tsebo ea saense ea libaktheria le tsamaiso ea 'mele ea motho ea ho itšireletsa mafung e ntse e tsoela pele, leha ho le joalo, bafuputsi ba se ba qalile ho sebetsana le liphello tse poteletseng tsa libaktheria tse ka' nang tsa etsahala lilemo tse ngata 'me li kenyelletsa ho sebelisana le litsela tse ngata.
Liphello tse joalo tsa baktheria li ke ke tsa hlahisa tšoaetso ha re ntse re nahana ka tšoaetso - ke hore, ha ho letho le bonahalang joaloka pneumonia, kapa letšollo la tšollo ea mali, kapa esita le feberu kapa sneeze.
Ho hlahisa baktheria: Motsoalle kapa Mobe?
Ho e-na le hoo, li-passenger li bonahala li se na molato bophelong - li-squatters tse se nang kotsi tse phelang mala a rōna le libakeng tse ling, tse ling tse tsejoang e le limela tse tloaelehileng. Lipalesa tse tloaelehileng li re thusa ka litsela tse sa tšoaneng, leha ho le joalo, bafuputsi ba lumela hore ho se leka-lekaneng mefuteng ea libaktheria tse nang le libaktheria tse fumanoang mofuteng o ka ba le karolo ho maloetse a rarahaneng, a kang li-syndromes tsa autoimmune, meriana, esita le kankere - ke maikutlo, bonyane.
Ha e le hantle, se fapaneng e ka 'na ea e-ba' nete. Tekanyo e nepahetseng ea libaktheria tsa intestinal e ka 'na ea e-ba le phello e sireletsang ha nako e ntse e feta maemong a mang. Kankere ke lefu le nang le mefuta e mengata, 'me ha ho motho ea batlang hore libaktheria li se ke tsa e-ba le senotlolo sa thibelo ea kankere, empa ena ke e' ngoe ea litsela tse ngata tse hlahlojoang.
Lingaka li 'nile tsa tseba nako e telele hore mefuta e itseng ea limela tsa "serapa" se nyenyane ka maleng e ka ba sa bohlokoa ho bophelo bo botle ba ho kula. Joalokaha bo-rasaense ba ntse ba tsoela pele ho ithuta lintho tse ncha mabapi le hore na tsamaiso ea 'mele ea motho ea ho itšireletsa mafung e sebetsa joang , le hore na libaktheria li sebelisana le eona joang, khopolo ea microbiome e hlahile: likokoana-hloko tsa motho li bua ka likokoana-hloko tsohle tsa rona' me li ka nkoa e le motsoalle oa motho genome - liphatsa tsohle tsa rona tsa lefutso.
Liphatsa tsa lefutso tsa microbiome ho feta boholo ba liphatsa tsa lefutso tsa genome ea rona ka hoo e ka bang 100 ho isa ho 1.
Khopolo ea lik'hemik'hale tse ntle le tse mpe ka microbiome e kentse letsoho le ho feta, ka mokhoa oa li-probiotics, li-prebiotics le lijo tse sebetsang.
· Probiotic e bolela likokoana-hloko tse phelang tse reretsoeng ho ba le melemo ea bophelo bo botle.
· Li- prebiotics li ka nkoa e le limatlafatsi tse itseng - hangata lik'habohaedreite tse fokolang ka mofuthu - tse "fepang" libaktheria tse ntle, kapa tse ling tse ka thusang ho etsa hore ho be le tekanyo e ntle pakeng tsa libaktheria tse nang le molemo le tse kotsi.
• Lijo tse sebetsang ke lihlahisoa tse nang le phello e ntle bophelong, ho feta phepo e nepahetseng.
Joalokaha u ka bona, tsela eo mantsoe ana a hlalositsoeng ka eona, ha ho na tiiso ea katleho-e leng se bontšang karolo ea bobeli ea saense le ho rarahana ha ho paka hore ho na le melemo ea sebele.
Baktheria le Kotsi ea Kankere
Bo-rasaense ba kile ba lumela hore libaktheria ha li bonahale eka li na le "lintho tse nepahetseng" tse bakang kankere, ho fapana le likokoana-hloko. Esita le kajeno, lethathamo la likokoana-hloko tse amanang le kankere ke nako e telele haholo ha li bapisoa le libaktheria. Le ha ho ntse ho ka 'na ha e-ba' nete hore likokoana-hloko li ka hlahisa malakabe a nts'etsopele ea ho bolaea ha li bapisoa le libaktheria, hape ke 'nete hore libaktheria li khona ho tlatsetsa ho nts'etsong ea likokoana-hloko tse itseng.
Mathoasong a bo-2000, mohlala, baktheria ea Helicobacter pylori - e tsejoang ka karolo ea eona ka lintlheng tsa mala - e ne e hokahane le kankere ea kankere. Hang ha bafuputsi ba bangata ba ntse ba nkoa e le "bo-rasaense ba bangata," ba shebile lihlopha pakeng tsa libaktheria le maloetse a mangata a kang kankere ha ba sa nkoa e le ba sa lokelang ho ba le maikutlo a bona le ho etsa lipatlisiso.
H. Pylori le Lymphoma
H. Pylori le MALT Lymphoma ea mala:
Mofuta o sa tloaelehang oa e seng Hodgkin's lymphoma o amahanngoa le baktheria H. Pylori. Kankere e bitsoa "marginal zone lymphoma ea li-mucosa-associated lymphoid tissue," kapa MALT, ka nakoana.
Litlaleho tsa Gastric MALT lymphoma li na le likarolo tse seng kae ho tse 20 tsa kankere tse qalang ka mpeng. Gastric MALT lymphoma e kenyelletsa li-lymphocyte tsa mofuta oa mofuta oa mofuta oa mofuta oa mofuta o mong, e leng mofuta oa sesepa sa 'mele oa ho itšireletsa mafung.
Coxiella Burnetii le ba bang
Libaktheria tse bakang tšoaetso e bitsoang Q Fever - Coxiella burnetii - li phunyeletse ka lebese, motsoako le lihlahisoa 'me li hlahisa li-amniotic fluid tsa liphoofolo tse nang le tšoaetso. Lihlopha tsa liphoofolo le batho ba sebetsang le liphoofolo ba kotsing haholo. Ka nako e itseng, ho nahanoa hore batho ba nang le lymphoma ba kotsing e kholo ea feberu ea Q.
Leha ho le joalo, phuputso e tlalehiloeng makasineng ea October 2015 ea "Mali" e fana ka maikutlo a hore batho ba nang le Q Fever ba ka 'na ba ba le monyetla oa hore ba hlahise lymphoma. Bafuputsi ba ile ba hlahloba bakuli ba 1 468 ba tšoaroang Setsing sa Boipheliso sa Sechaba sa Fora sa Q Fever ho tloha ka 2004 ho ea ho 2014 'me ba fumana batho ba supileng ba hlahisitseng lymphoma ka mor'a tšoaetso ea C. burnetii. Ho ile ha fumanoa bakuli ba tšeletseng ba nang le B-cell lymphoma e khōlō le e nang le follicular lymphoma. Likokoana-hloko tsena le tse ling li ka 'na tsa e-ba le khokahanyo ea lymphoma maemong a mang, empa lipatlisiso ho sheba potso ena li ntse li tsoelapele.
Ho ithuta Lymphoma Risk le Gut Bacteria
Bo-rasaense ba UCLA ba thahasella hore na mobu oa libaktheria o ka 'na oa ama nts'etsopele ea kankere e' nile ea leka litlhahiso tsa bona joang litoebeng tse nang le lefu la liphatsa tsa lefutso le amanang le lefu la liphatsa tsa lefutso, telxectisia ea ataxia.
Ho batho, telangectasia ea ataxia, kapa AT, ke lefu le feteletseng la liphatsa tsa lefutso la bongoana le hlahang ho motho a le mong ho ba 100 000. Batho ba nang le AT ba atisa ho hlaolela likokoana-hloko tsa lymphoid ho feta tse ling. Hoo e ka bang karolo ea 30 ho ea ho ea 40 lekholong ea bakuli ba AT e ba le kankere ea mofuta o itseng nakong ea bophelo ba bona, 'me karolo ea 40 lekholong ea likokoana-hloko ho bakuli ba AT ke li-lymphomas tseo e seng tsa Hodgkin , tse etsang karolo ea 20 lekholong ke lucphocytic leukemias,' me karolo ea 5 lekholong ke lymphomas tsa Hodgkin.
Lipatlisong tsa liphoofolo tsa bona, bafuputsi ba ile ba sebelisa litoeba tse nang le liphatsa tsa lefutso tsa ATM, tse ikarabellang bakeng sa litekanyetso tse phahameng tsa kankere ea mali, lymphomas le mafu a mang a kankere.
Litoeba tse ling li ne li fanoa feela ka libaktheria tse khahlanong le ho ruruha 'me tse ling li kopane le likokoana-hloko tse chesang le tse hlekefetsang. Lipatlisiso li bontšitse hore nts'etsopele ea lymphoma e liehile ho tsoa ho litoeba tse fumanang libaktheria tse khahlanong le ho ruruha feela.
Kamoo Bacteria e ka Fetolang Kotsi?
Joale bafuputsi ba ile ba sebelisa mokhoa o tšoanang oa ho etsa liteko, o akarelletsang litoeba, ho hlahloba kamoo maqhubu a baktheria a ka 'nang a lieha ho qala ha lymphoma. Ba fumane hore litoeba tse fumanoang feela libaktheria tse khahlanong le ho ruruha li sireletsehile metabolites tse tsejoang ho thibela kankere mantle a bona le morong. Litoeba tse fuoeng "libaktheria tse ntle" li ne li boetse li bonahala li senya limatlafatsi tse itseng ka tsela eo ho lumeloa hore e baka kotsi ea kankere.
Litoeba tse nang le libaktheria tse khahlanong le ho ruruha li ile tsa hlahisa lymphoma butle-butle ho feta litoeba tsa ho bapisa. Libaktheria tse molemo li boetse li ekelitse bophelo ba litoeba tse 'nè bophelong bohle,' me li fokolise tšenyo ea DNA le ho ruruha.
Tšepo ke hore li-probiotics li ka 'na tsa thusa ho fokotsa kotsi ea ho tšoaroa ke kankere ka li-anti-inflammatory properties .
Lisebelisoa:
Cheema AK, Maier I, Dowdy T, et al. Metabolite ea Chemopreventive e Kopantsoe le Phetoho ea Intestinal Microbiota e Lekanngoeng ho Litoeba le ho Fokotsa Carcinogenese. PLoS One. 2016; 11 (4): e0151190.
Koahela TL, Blaser MJ. Helicobacter Pylori ho Bophelo le Mafu. Gastroenterology. 2009; 136 (6): 1863-1873.
Hansson LE, Nyrén O, Hsing AW, et al. Kotsi ea Kankere ea Mala a Mokuli a Nang le Maloetse a Gastric kapa Duodenal Ulcer. N Engl J Med. 2006; 335: 242-249.
National Cancer Institute. Helicobacter Pylori le kankere.
Melenotte C, M limilione, Audoly G, et al. Bacterium e Etsang Hore Feberu ea Q e amana le Lymphoma e sa Hodgkin. Mali . 2015.
National Cancer Institute. Helicobacter Pylori le kankere.
Robbiani DR, Deroubaix S, Feldhahn N et al. Bothata ba Plasmodium Infection bo Ntšetsa Pele ho Hlokahala ha Genomic le A-B e theolelang ea Cell Lymphoma. Cell 13 August 2015; 162 (4): 727-737.