Hypothalamus ke karolo ea bohlokoa ea tsamaiso ea hau ea pelo. E laola likamano pakeng tsa endocrine kapa tsamaiso ea hau ea hormone le likarolo tse ling tsa tsamaiso ea hau ea methapo. Your hypothalamus ke boikarabelo ba ho hlahisa hormone e bakang qaleho ea ho ea khoeling.
Hypothalamus e Teng Hokae?
Haeba u hula mohala ho tloha bohareng ba lintši tsa hao ho khutlela bohareng ba boko ba hao u tla fumana sebopeho sa pea se bitsoang hypothalamus.
Seo karolo ena ea boko e se nang boholo bo etsoa bakeng sa mosebetsi.
Hypothalamus E Etsa'ng?
Nahana ka hypothalamus e le "mokhoa o bohlale oa ho laola lapeng" oa 'mele oa hau. Boikarabelo ba eona bo ka sehloohong ke ho boloka 'mele oa hau o sebetsa hantle le ho tsitsitse. The hypothalamus controls le ho tsamaisana le mesebetsi e mengata ea boipheliso ea 'mele oa hau joaloka molaetsa oa mocheso, tlala, lenyora, boroko le maikutlo. Ka ho nka bohato bo arabelang ka boitsebiso bo tsoang bokong le ho tsoa litsing tse ling tsa tlhahiso ea hormone 'meleng, hypothalamus e fetola ho leka-lekana ka hare ho' mele kapa homeostasis.
Mosebetsi o mong oa bohlokoa oa hypothalamus ke ho laola mohala oa pituitary . Hypothalamus e hlahisa lintho tse bitsoang ho lokolla li-hormone tse etsang hore pituitary e khone ho hlahisa likarolo tse ling tse hlahisang li-hormone tsa 'mele oa hau joaloka thyroid le ovary . Ka ho laola ho lokolloa ha lihomone tsena, hypothalamus e boetse e ameha ka ho toba ka metabolism ea hao, kgolo, ho kopanela liphate, le ka nako ea ho ea khoeling.
Ho ilela khoeli nako ea ho laola
Your hypothalamus e hlahisa hormone e bitsoang GnRH kapa gonadotropin e lokollang hormone. Tlas'a maemo a tloaelehileng, 'mele oa hau o lokolla GnRH ka mokhoa o fokolang. Phetoho ena e khutšoanyane e etsa hore lesela la pituitary le tsamaisane le ho lokolloa ha lihomone tse ling tse peli tse bitsoang FSH kapa follicle e susumetsang hormone le li-hormone tsa LH kapa li-luteinizing.
FSH, le eona, e etsa hore ovary e hlahise estrogen le LH e susumeletsa leqeba ho hlahisa progesterone. Liphetoho tsa li-hormone tsena li na le boikarabello ba nako ea ho ea khoeling eo ho kenyelletsang ho lila le haeba ho se na palo kapa bokhachane, ho ea khoeling kapa nako.
Ha Lintho li E-ea Phoso
Kaha hypothalamus ke karolo ea taolo ea nako ea ho ea khoeling, maemo a mang a ferekanyang boemo ba 'mele le ho kena-kenana le ho sebetsa hantle ha hypothalamus ho ka boela ha kena-kenana le nako ea ho ea khoeling. Ha ho lokolloa ha GnRH ho sa sebetse ka mokhoa o tloaelehileng oa pulsatile, FSH le LH ha li hlahisoe ka hloko ke lesela la pituitary. Kantle le ho susumetsoa ke li-hormone tsena, mae a bomme ha a hlahise estrogen le progesterone le ho phalla ha ho hlahe. Ntle le ho tšoaetsoa, ha ho na ho ea khoeling.
Mantsoe a theknoloji bakeng sa ho lahleheloa ke nako ea hau ke ea tlhahiso ea mali kapa ea sebele ntle le mali. Ha o lahleheloa ke nako ea hau hobane hypothalamus ea hau ha e sebetse ka tloaelo e bitsoa hypothalamic amenorrhea. Lisosa tse tloaelehileng tsa hypothalamic amenorrhea li kenyelletsa:
- khatello ea kelello ea kelello
- khatello ea physiologic
- boloetse bo sa foleng
- ho ikoetlisa ka tsela e feteletseng
- ho lahleheloa ke boima ba 'mele
Hypothalamic amenorrhea ke sesosa se tloaelehileng sa linako tse lahlehileng.
Ho itšetlehile ka tekanyo le nako ea khatello ea kelello 'meleng oa hao u ka' na ua hloloheloa nako le nako kapa u ka khaotsa ho ea khoeling ka ho feletseng.
Ho laola Setsi sa Tsamaiso
Ho utloisisa bohlokoa ba ho lokolloa ha GnRH ka nako e khutšoanyane ho tsoa ho bafuputsi ba susumelitsoeng ke hypothalamus ho hlahisa mofuta oa meriana e fokolang tlhahiso ea mae a bomme ea estrogen le progesterone. Ho boloka boemo ba GnRH bo tsitsitseng maling a hao ho fokotsa pituitary ea tokoloho ea FSH le LH e fanang ka ho thibela tlhahiso ea li-ovarian ea estrogen le progesterone. Sehlopha sena sa meriana e tsejoang e le gonadotropin-ho lokolla li-agonists tsa hormone e kenyelletsa leuprolide acetate kapa Lupron le goserelin acetate kapa Zoladex.
Meriana ena e na le karolo ea bohlokoa ho phekola maemo a 'maloa a basali a kang uterine fibroids le endometriosis.
Lentsoe le Tsoang ho
Ka linako tse ling o lahleheloa ke nako ea hao e ka 'na ea e-ba ntho e tloaelehileng ea' mele oa hao ha u hatelleha. Empa ho lahleheloa ke nako ea hao ka ho khetheha likhoeli tse 'maloa ka tatellano e ka ba pontšo ea bothata bo ka sehloohong kapa ho se leka-lekane ho itseng' meleng oa hau.
Joalo ka linako tsohle, haeba u e-na le mathata leha e le afe ka nako ea ho ea khoeling, ka kōpo buisanang le mofani oa tlhokomelo ea bophelo.
E fetotsoe ke: Andrea Chisholm MD
> Mohloli:
> Reed BG, Carr BR. Mokhoa o tloaelehileng oa ho ea khoeling le ho laoloa ha ho qeta ho thula. [Ho hlophisitsoe ka la 2015 May la 22]. Ka: De Groot LJ, Chrousos G, Dungan K, et al., Bahlophisi. Tlhaloso ea litaba [Internet]. South Dartmouth (MA): MDText.com, Inc .; 2000 -E fumaneha ho: https://www.ncbi.nlm.nih.gov/books/NBK279054/