Meriana ea Meriana ea Antidiuretic Hormone (ADH) ho fokotsa Likotsi
Meriana ea ngaka ea desmopressin (eo ka linako tse ling e bitsoang DDAVP) ke lithethefatsi tse etsisang hormone ea tlhaho 'meleng' me e sebelisetsoa ho phekola enuresis ea motšehare, kapa maemo a mang. Haeba litlhare tsa boitšoaro li hlōleha, demopressin ke lithethefatsi tse sebetsang ka ho fetisisa ho thusa bana ho emisa ho robala bethe. Sebaka sa demmopressin ke eng, se sebetsa joang, hona ke litla-morao life?
Lisebelisoa
Desmopressin e sebelisoa hangata ho phekola bedwetting ho bana ba lilemo li tšeletseng kapa ho feta. Boemong bona, thibelo ea metsi a tlameha ho tsamaea le tsamaiso ea meriana nakong ea ho robala. Thibelo ena hangata e tlameha ho feta hora e le nngwe pele e e-ba le desmopressin ho fihlela hoseng ho latelang (kapa hoo e ka bang lihora tse robeli ka mor'a hore meriana e nkiloe).
Desmopressin e boetse e sebelisoa ho sebetsana le maemo a mang a tloaelehileng, ho akarelletsa:
- Mofuta o moholo oa lefu la tsoekere insipidus (tlhahiso ea urine e hlapolang)
- Hemophilia A
- Ho tsoa mali a 'mele
- Mofuta oa 1 oa lefu la Willebrand
E Sebetsa Joang?
Desmopressin ke lithethefatsi tse etsisang hormone ea tlhaho 'meleng o bitsoang antidiuretic hormone . Ka lebaka leo, e khona ho fokotsa diuresis kapa tlhahiso ea moroto liphio tse qetellang li isoa senya.
Ho phaella moo, demmopressin e eketsa lik'hemik'hale tse nang le mali a bitsoang Factor VIII le von Willebrand factor, tse bohlokoa ho khaotsa ho tsoa mali le ho hlahisa mahlaseli.
Sena se hlalosa likarolo tse ling tsa sona ho feta ho phekola litoro.
Ke Mang ea sa Lokelang ho Sebelisa Desmopressin?
Desmopressin ha ea lokela ho sebelisoa ho sebetsana le ho robala bethe ho bana ba banyenyane ho feta lilemo tse tšeletseng. Ho phaella moo, meriana ha ea lokela ho sebelisoa nakong ea maloetse a ka 'nang a ama ho kenngoa ha metsi kapa ho lekanngoa ha electrolyte (e kang letšollo kapa ho hlatsa).
Ho phaella moo, batho ba nang le mathata a liphio, histori ea sodium e tlase (e bitsoang hyponatremia), kapa le von Willibrand lefu la mofuta oa IIB ha baa lokela ho sebelisa lesmopressin.
Ho na le maemo a mangata ao ho 'ona demmopressin e lokelang ho sebelisoa feela ka tlhokomelo, ho akarelletsa le lefu la methapo ea mali, khatello e phahameng ea mali (khatello ea kelello), ho se leka-lekana ha motlakase (electrolyte), polydipsia (ho noa haholo), cystic fibrosis, kotsi ea ho thibela (thrombosis), le ho bakuli ba hōlileng.
Desmopressin e na le monyetla oa ho sebelisana le lithethefatsi tse ngata, kahoo meriana ea morao-rao e lokela ho hlahlojoa ka hloko ke mofani oa tlhokomelo ea bophelo pele u qala ho e sebelisa.
Liphello tse Tloaelehileng
Ho na le litla-morao tse seng kae tse ka bang le litla-morao ka tšebeliso ea desmopressin. Le hoja motho a ke ke a lebelloa hore a be le litla-morao tse ngata - 'me e ka' na eaba ha a na leha e le efe ea tsona - tse ling tse ka 'nang tsa etsahala ka desmopressin li kenyeletsa:
- Flushing
- Lipere
- Hlooho ea hlooho
- Sehlōhō
- Ho halefa ha mahlo (conjunctivitis)
- Ho halefa ha Nasal (rhinitis)
- Nosebleeds (epistaxis)
- Ho tsuba
- Nausea
- Bohloko ba mpa
Liketsahalo Tse ka 'Nang Tsa E-ba le Bohlokoa
Ka tšebeliso ea lithethefatsi leha e le life, ho kenyelletsoa lesmopressin, ho na le kotsi ea litla-morao tse tebileng. Tsena li etsahala hangata haholo, empa tse ling tse ka 'nang tsa etsahala ka tšebeliso ea desmopressin li kenyeletsa:
- Sodium e phahameng (hyponatremia)
- Ho noa metsi
- Ho khaotsa
- Anaphylaxis (e matla ho itšoara hantle ho akarelletsa ho phefumoloha ho thata)
- Ho roala (thrombosis)
Litlhokomeliso tsa polokeho le tlhokomelo
Joalokaha ho boletsoe ka holimo, batho ba bang ba lokela ho sebelisa demopressin ka hloko kapa che. Ha meriana e sebetsa liphio, ke habohlokoa ho etsa mosebetsi o tloaelehileng oa liphio ka ho lekanya créinine maling a hau pele u qala meriana.
Haeba u e-na le mathata leha e le afe ka tšebeliso ea desmopressin, u lokela ho ba haufi le mofani oa hao oa tlhokomelo ea bophelo bo botle.
Mohloli:
"Desmopressin." Epocrates Rx Pro. Phetolelo ea 3.16, 2011. Epocrates, Inc. San Mateo, California.