Melemo ea Bophelo, Mesebetsi, Litlhahiso le Tse ling
Melatonin ke eng?
E hlahisitsoe ka tlhaho 'meleng, melatonin ke hormone e thusang ho laola ho robala ha' mele oa 'mele le li-hormone tse sa tšoaneng' meleng. E entsoe ka amino acid tryptophan.
'Mele o hlahisa melatonin nakong ea lefifi (ho lokisetsa boroko) le ho thibela tlhahiso nakong ea khanya. Ho ea ka baeletsi ba bang, ho nka melatonin ka mofuta oa metsoako ea melatonin e tlatsetso e ka thusa ho ntlafatsa boroko.
Lilemong tsa bo-1970 le bo-1980, lipatlisiso tse amang liphello tsa melatonin ha li robala li entse hore ho sebelisoe lisebelisuoa tsa melatonin e le phekolo e fapaneng bakeng sa mathata a ho robala. Bohareng ba lilemo tsa bo-1990, ho tsebahala ha melatonin ho tlatsetsa bakeng sa jet lag le mathata a itseng a amanang le lilemo a eketsehile haholo.
Lisebelisoa tsa Melatonin
Mefuteng e meng ea phekolo, li-supplement ea melatonin li sebelisetsoa ho fetola mokhoa oa ho robala oa 'mele' me li boleloa ho thusa ka litlhoko tse latelang tsa bophelo bo botle:
- Mokhathala oa sefofane
- Ho tsieleha
- Mathata a ho robala ka lebaka la mosebetsi oa ho fetoha
- E liehetsoe ke Phalliso ea Phallano ea Boroko
- Ho hlobaela ho amana le bothata ba ho se tsotelle (ADHD), autism, cerebral palsy le bofofu.
- Ho thusoa ka boroko ka mor'a ho khaotsa meriana ea benzodiazepine
- Ho fokotsa litla-morao tsa ho khaotsa ho tsuba
- Ho se robale ka lebaka la tšebeliso ea meriana (mohlala, beta-blockers)
Ba bang ba ts'ebelisitsoeng ba bolela hore melatonin e ka loantša mefuta e meng ea kankere hape e fokotsa tse ling tsa litla-morao tsa chemotherapy.
Ho feta moo, ho boleloa hore melatonin e thusa ka ho hlobaela e amanang le maemo a kang a Alzheimer's disease, depression, le schizophrenia.
Melemo ea Bophelo ea Melatonin
Mona re shebile ka hloko tšebeliso ea melatonin ka meriana e meng le melemo ea bophelo bo botle:
1) Jet Lag
Ho tsamaea ho pholletsa le likarolo tsa nako ho ferekanya pina ea circadian.
Bopaki ba pele bo bontša hore li-supplement tsa melatonin li ka fokotsa matšoao a itseng a jet-lag, haholo-holo ho batho ba eang bochabela le / kapa ba tšela libaka tse hlano kapa ho feta. Melatonin e ka ntlafatsa ho falimeha motšehare, ho tsamaisana ha mokhatlo, le ka tekanyo e nyane, mokhathala oa motšehare.
Liphetho tse molemohali li bonahala li etsahala ha lisebelisoa tsa melatonine li qala ka letsatsi la maeto le ho nkoa ka nako ea boroko e lakatsang ho ea moo u eang teng. Hangata ho nkoa matsatsi a seng makae.
Tse amanang: 5 Litlhare tsa Tlhaho Tse Lokelang ho li Qoba Jet Lag .
2) ho hlobaela
Melatonin e bonahala e fokotsa nako ea ho robala, empa ka metsotso e 12 feela (ho latela thuto e le 'ngoe). Liphuputso tse 'maloa li bontša hore nako e nepahetseng ea ho nka li-supplemental melatonin e pakeng tsa halofo le hora le lihora tse peli pele ho nako ea ho robala. Ho na le bopaki bo bong bo bontšang hore melatonin e ka 'na ea thusa batho ba hōlileng haholo, mohlomong hobane e ka ba le melatonin e nyenyane' meleng ea bona. Liphuputso tse ngata li 'nile tsa e-ba tse nyenyane le tse khutšoanyane ka nako e telele, kahoo lipatlisiso tse eketsehileng lia hlokahala
Sheba Litlhahiso tse 14 tsa Tlhaho ho Laola Insomnia .
3) Tsamaiso ea ho sebetsa
Le hoja mosebetsi oa bosiu oa khatiso o sitisa pina ea circadian, ho na le bopaki bo fokolang bo tšehetsang khopolo ea hore melatonin e ka fetola kemiso ea boroko ho batho ba sebetsang bosiu le ba robalang motšehare.
Ha e bonahale eka e ntlafatsa boroko ka mor'a mosebetsi oa ho fetoha kapa ho ntlafatsa temoho nakong ea mosebetsi oa ho fetoha.
4) Mathata a Boroko a Amanang le Bokooa
Melatonin e ka ntlafatsa mathata a boroko ho batho ba foufetseng.
5) Ho lieha ho qeta Phase ea Boroko Syndrome
Melatonin e 'nile ea phenyekolloa bakeng sa batho ba nang le lefu la boroko la ho robala. Lipatlisiso li bontša hore ho ja libeke tse 'nè letsatsi le leng le le leng ho ka ntlafatsa boroko, ka ho fokotsa nako ea ho robala le ho ntlafatsa nako ea ho robala. Leha ho le joalo, pele selemo se le seng sa ho khaotsa ho tlatsetsa, ho khutlela mefuteng ea ho robala pele ho kalafo ho hlokometsoe.
6) Mathata a Boroko a Amanang le Mathata a Tsoelo-pele
Ho bile le lipatlisiso tse 'maloa tsa pele le litlaleho tsa liketsahalo mabapi le tšebeliso ea melatonin ho bana ba nang le mathata a bakoang ke mathata a ho robala, a kang likooa tsa autism, dispery, kapa lefu la sethoathoa. Liphuputso tse entsoeng ho fihlela mona li fana ka maikutlo a hore melatonin e ka khutsufatsa nako ea ho robala le nako e telele ea ho robala. Leha ho le joalo, litla-morao le polokeho ea melatonin ea nako e telele kapa e tloaelehileng ho bana ha e tsejoe.
Etsa leqepheng la 2 ho ithuta ka tse ling tsa lintho tse ka 'nang tsa e-ba teng ka ho sireletsa ...
Lithako
Le hoja ka kakaretso lipatlisiso li sheba ho sebelisoa ha melatonin ka likhoeli tse peli, litla-morao le polokeho ea tšebeliso ea nako e telele kapa e tloaelehileng ea li-supplement ea melatonin ha e tsejoe. Litsebi tse ling li nahana ka tekanyo e atisang ho fumanoa mefuteng e mengata ea melatonin, limiligrama tse 3 ho isa ho tse 5, e le hore e phahame haholo 'me e re e lekane ho tloha ho 0,1 ho isa ho 0.5 milligrams e utloahalang.
Melatonin li-supplement ha lia lokela ho nkoa ke bana kapa lilemong tsa bocha, hobane ho na le ho ameha ho itseng hore melatonin e tlatsetsa e ka senya tsoelo-pele ea likhukhuni. Tekanyetso e phahameng ea melatonin e ka 'na ea e-ba le tšusumetso e thibelang ho tsoala. Basali le basali ba nang le bakhachane le ba anyesang ba lekang ho ima ba lokela ho qoba ho sebelisa melatonin.
Litla-morao tsa melatonin li ka 'na tsa kenyelletsa ho otsela, ho robala hlooho, mokoloko, litoro tse hlakileng, liphetoho tsa nakoana ea nakoana, le ho fokotseha ha nakoana ho tlhokomelo le tekano. Batho ha baa lokela ho khanna kapa ho sebelisa mechine ka lihora tse hlano ka mor'a ho nka melatonin. Melatonin e ka 'na ea baka maqeba a mpa, ho nyekeloa ke pelo, le ho hlatsa, khatello e tlase ea mali, le ka seoelo, maikutlo a fokolang kapa phallo.
Melatonin e ka eketsa kotsi ea ho tsoa mali, kahoo ha ea lokela ho sebelisoa ke batho ba sebelisang warfarin (Coumadin®) kapa meriana e meng e amang tšollo ea mali kapa batho ba nang le mathata a tsoa mali.
Melatonin e susumetsa tlhahiso ea lihomone tse ling.
Ho eketseha ha lebese la banna le ho fokotsa palo ea peō ho tlalehiloe. Melatonin e ka boela ea ama tsoekere ea mali le lisosa tsa insulin.
Melatonin e ka ama tšusumetso ea 'mele. Ha ho tsejoe hore na e tla ama batho ba nang le maemo a ho iketsetsa metsi a kang multiple sclerosis , psoriasis , lefu la Crohn , lefu la ramatiki la mafu , lefu la lupus le mofuta oa lefu la tsoekere oa mofuta oa 1.
Ha ea lokela ho nkoa ke batho ba kenyang lijo.
Melatonin li-supplement li ka mpefatsa matšoao ho batho ba nang le khatello ea kelello, kahoo batho ba nang le khatello ea kelello ba lokela ho sebelisa melatonin feela tlas'a tlhokomelo ea mofani oa tlhokomelo ea bophelo. E ka boela ea eketsa kotsi ea ho tšoaroa ke batho ba nang le mathata a ho tšoaroa ke lefu. Melatonin e robehile ke sebete, kahoo batho ba nang le lefu la sebete ba ka 'na ba hloka ho qoba melatonin.
Melatonin e ka 'na ea sebelisana le lithethefatsi' me ea tlatsetsa e kang:
- Meriana e phahameng ea mali
- Lithethefatsi tse thibelang tsamaiso ea 'mele ea ho itšireletsa mafung, e kang cyclosporine
- Ho imeloa kelellong meriana
- Corticosteroids (e sebelisetsoang maemo a ho ruruha a kang arthritis)
- Benzodiazepines, tse kang diazepam le lithethefatsi tse ling tse bakang sedation
- Litlama tse bakang boroko kapa ho otsela, tse kang kava kava le valerian
- Mokhooa oa setlama oa St. John
Ho sebelisa Melatonin bakeng sa Bophelo bo Botle
Ke habohlokoa ho hlokomela hore ho itlhokomela le ho qoba ho hlokomela tlhokomelo e tloaelehileng ho ka ba le liphello tse tebileng. U ka fumana litlhahiso tsa ho sebelisa lisebelisoa tse teng mona , empa haeba u nahana ka tšebeliso ea melatonin bakeng sa morero leha e le ofe, etsa bonnete ba hore u buisane le mofani oa hao oa tlhokomelo ea mantlha pele.
Lisebelisoa:
Buscemi N, Vandermeer B, Hooton N, le al. Matla le polokeho ea melatonin e ngata bakeng sa mathata a mathomo a boroko. Tlhahlobo ea meta. J Gen Intern Med 2005; 20: 1151-8.
Fischer, S., Smolnik, R., Herms, M., Born, J., le Fehm, HL Melatonin e ntlafatsa ka mokhoa o matla oa ho haha boroko ho batho ba foufetseng. J Clin Endocrinol.Metab 2003; 88 (11): 5315-5320.
Gringras P, Gamble C, Jones AP, le al; MENDS Sehlopha sa Thuto. Melatonin bakeng sa mathata a boroko ho bana ba nang le bothata ba neurodevelopmental: tlhahlobo e laoloang ea placebo e laoloang ka bobeli. BMJ. 2012 Nov 5; 345: e6664.
James M, Tremea MO, Jones JS, Krohmer JR. Na melatonin e ka ntlafatsa ho feto-fetoha ha bosiu? Am J Emerg Med 1998; 16: 367-70.
Jan, JE, Hamilton, D., Seward, N., Fast, DK, Freeman, RD, le Laudon, M. Litlhahlobo tsa meriana ea melatonin e laolang ho laola bana ba nang le mathata a potoloho ea ho robala. J Pineal Res 2000; 29 (1): 34-39.
Nagtegaal JE, Laurant MW, Kerkhof GA, et al. Liphello tsa melatonin ka boleng ba bophelo ho bakuli ba fokolang lefu la sekhahla sa boroko. J Psychosom Res 2000; 48: 45-50.
Tekanyetso ea tlhaho. "Melatonin" Mayoclinic.com. E fihlile ka la 3 October, 2007.
PDRHealth. "Melatonin" e fihlile ka la 3 October, 2007.
Rossignol, DA le Frye, RE Melatonin ka mathata a autism: ho hlahloba ka mokhoa o hlophisitsoeng le ho hlahloba litlhahlobo. Dev.Med.Child Neurol. 2011; 53 (9): 783-792.
Sack RL, Brandes RW, Kendall AR, le al. Ho kenngoa ha lipina tsa melcaine ka melatonin ho batho ba foufetseng. N Engl J Med 2000; 343: 1070-7.
Taba e nepahetseng: Boitsebiso bo boletsoeng setšeng sena bo reretsoe merero ea thuto feela 'me ha bo nkele sebaka keletso, ho hlahlojoa kapa kalafo ke ngaka e nang le tumello. Ha e reretsoe ho koahela mekhoa eohle ea tlhokomelo, likamano tsa lithethefatsi, maemo kapa liphello tse bohloko. U lokela ho batla thuso ea meriana hang-hang bakeng sa bophelo bo botle le ho buisana le ngaka pele u sebelisa mefuta e meng ea phekolo kapa u etse phetoho tsamaisong ea hau.