Na Thiamine-e Nkiloe ka Tlatsetso ea Thuso?
Benfotiamine ke ntho e tsoang ho thiamine (vithamine ea B e boetse e tsejoa e le vithamine B1). Ho buuoa ka benfotiamine ho boleloa ho phahamisa likarolo tsa thiamine le ho sireletsa khahlanong le maemo a bophelo bo amanang le maemo a tlaase a thiamine.
Thiamine e fumanoa lijong tse sa tšoaneng tse akarelletsang nama, likhoho, mahe, le lijo tse nang le liqhobosheane tse kang bohobe, lijo-thollo, pasta, raese le phofo.
Batho ba jang haholo lik'habohaedreite tse hloekisitsoeng (tse kang raese e tšoeu le lihlahisoa tse sa tšoeu tse hlahisoang ka phofo) kapa ho qoba lijo-thollo li ka ba kotsing e kholo ea ho haella ha thiamine, joalo ka ba nang le letšollo, lefu la Crohn le ho itšetleha ka joala. Boikoetliso bo matla le maemo a kang hyperthyroidism a eketsa tlhokahalo ea 'mele ea thiamine.
Lisebelisoa
Maemong a tlaase a thiamine a amahanngoa le mathata a mangata a bophelo bo botle, ho kenyelletsa le methapo ea pelo le mathata a pelo. Kaha benfotiamine e bonahala e e-na le bioavailability e phahameng le ho nkoa ke 'mele ho feta thiamine, batho ba bang ba e sebelisa ho eketsa maemo a thiamine le ho laola maemo a itseng a bophelo.
Ka mohlala, benfotiamine e atisa ho etsoa e le pheko ea tlhaho bakeng sa maemo a latelang:
- Ho tšoenyeha
- Bohloko bo khutlang
- Ho tepella maikutlong
- Lefu la tsoekere
- FIbromyalgia
- Neuropathy (e akarelletsang lefu la tsoekere la lefu la tsoekere le ho ba le bothata ba kelello ea joala)
- Sciatica
- Lefu la qoqotho (joalo ka lefu la Hashimoto)
Ho phaella moo, benfotiamine ho boleloa hore e liehisa botsofali, ho ntlafatsa ts'ebetso ea boikoetliso, ho matlafatsa maikutlo, ho ntlafatsa boko bo sebetsang, le ho fokotsa lactic acid buildup 'meleng.
Baeletsi ba bang ba boetse ba fana ka tlhahiso ea hore benfotiamine e ka sireletsa 'mele liphellong tse kotsi tsa lihlahisoa tse tsoetseng pele tsa glycation (li-AGEs).
Mofuta oa motsoako o fumanehang nama le lijo tse ling (haholo-holo tse halikiloeng, tse halikiloeng, tse halikiloeng, kapa lijo tse halikiloeng), li-AGE li ka baka ho ruruha 'me tsa kenya letsoho linthong tse ngata tsa bophelo bo botle.
Melemo
Ho fihlela joale, liphuputso tse seng kae feela li hlahlobile melemo ea bophelo bo botle ka ho nka li-supplementary benfotiamine. Mona re shebile liphuputso tse ling tsa thuto:
1) Lefu la tsoekere
Benfotiamine e ka 'na ea e-ba le molemo o itseng ho batho ba nang le lefu la tsoekere, ho ea ka phuputso e phatlalalitsoeng ho Diabetes Care ka 2006. Bakeng sa thuto, batho ba 13 ba nang le lefu la tsoekere la mofuta oa 2 ba ile ba fuoa lijo tse nang le litaba tse phahameng tsa li-AGE pele ho kamora matsatsi a mararo mg ea benfotiamine letsatsi le letsatsi. Liphello tsa thuto li bontšitse hore benfotiamine e hlahile ho sireletsa khahlanong le khatello ea kelello e bakoang ke ho kenngoa ha li-AGE.
Phuputsong ea 2010 e hatisitsoeng ka Ts'oaetso ea Ts'oaetso , leha ho le joalo, bafuputsi ba batlisitse phello ea benfotiamine ho batho ba nang le lefu la tsoekere la mofuta oa 2 le nephropathy. Bakeng sa thuto, barupeluoa ba ile ba nka benfotiamine kapa letsatsi le leng le le leng bakeng sa libeke tse 12. Lipatlisiso li senoletse hore benfotiamine ha ea ka ea fokotsa ho ntša albin excretion (tlhahlobo e sebelisetsoang ho hlahloba mafu a liphio) kapa maemo a KIM-1 (letšoao la ho lematsa ha liphio).
Phuputso ea libeke tse 12 e phatlalalitsoeng PLOS One ka 2012 e fumane hape hore benfotiamine ha ea ka ea ama likarolo tse lebisang ho mathata a bakoang ke lefu la sekoli.
Tse amanang: Litlhare tsa Tlhaho bakeng sa lefu la tsoekere
2) Lefu la lefu la tsoekere
Liphuputso tse 'maloa tse nyenyane li bontša hore benfotiamine e ka thusa ho phekola lefu la tsoekere la lefu la tsoekere (boemo bo tšoaetsanoang ke ts'oaetso ea meriana e bakoang ke ho phahama ha tsoekere e amanang le tsoekere ea mali).
Phuputso ea 2012 ho tsoa ho Ts'ehetso ea Ts'oaetsong , leha ho le joalo, e fumane hore phekolo ea likhoeli tse 24 le benfotiamine e ne e se na liphello tse kholo ts'ebetsong ea methapo ea meriana kapa matšoao a ho ruruha ho barupeluoa ba nang le lefu la tsoekere la mofuta oa 1.
3) Maloetse a Alzheimer
Benfotiamine e bonts'a tšepiso ea ho phekoloa ha lefu la Alzheimer , ho ea ka thuto e nyenyane ea 2016 e phatlalalitsoeng ho Neuroscience Bulletin .
Batho ba bahlano ba nang le lefu la Alzheimer le bonolo ho isa boemong bo itekanetseng ba ile ba nka benfotiamine (300 mg ka letsatsi) ka likhoeli tse 18.
Qetellong ea thuto, barupeluoa ba bahlano ba bontšitse ntlafatso ea ho tseba. Bafuputsi ba ile ba hlahloba bararo ba barupeluoa ka mokhoa oa PET oa ho hlahloba 'me ba fumana ntlafatso ha ba bapisoa le maikutlo a bona a pele.
Liphello tse ka khonehang
Le hoja ho tsejoa hanyane ka tšireletso ea ho nka benfotiamine ka nako e telele, ho na le ho ameha ho itseng hore li-supplemental benfotiamine li ka hlahisa litla-morao tse itseng (tse kang ho ferekane, ho nyeheloa ke pelo, ho ba le setulong, ho lahleheloa ke moriri, ho ba le boima ba 'mele, monko oa' mele le ho fokotseha khatello ea mali).
Batho ba nang le kutloelo-bohloko sebabole ba lokela ho qoba benfotiamine.
Mokhoa o sireletsehileng le o sebetsang ka ho fetisisa oa benfotiamine ha o tsejoe hona joale. Haeba u ntse u nahana ka tlatsetso, bua le mofani oa hao oa tlhokomelo ea bophelo ho fumana hore na, haeba ho na le, tekanyo ea benfotiamine e nepahetse ho uena.
Hape, hopola hore polokeho ea liphallelo ho basali ba nang le bakhachane, bo-'mè ba tlhokomelo, bana le ba nang le maemo a bophelo kapa ba noang meriana ha e e-s'o thehoe. U ka fumana litlhahiso tse eketsehileng mabapi le ho sebelisa li-supplements mona .
Moo U ka e Fumanang
E fumaneha haholo ka ho reka Inthaneteng, li-supplement tsa benfotiamine li ka boela tsa fumanoa lijong tse ngata tsa tlhaho libakeng le mabenkeleng a khethehileng ka lijo tse ling tsa lijo.
Thepa
Le hoja benfotiamine e ka ba tlatsetso e tšepisang bakeng sa lefu la Alzheimer, mathata a lefu la tsoekere, le maemo a mang a amang lihlahisoa tse tsoetseng pele tsa glycation, hase lithuto tsohle tse bontšitseng melemo. Re ke ke ra tiea ka tumellano ho fihlela ho na le liteko tse kholo tsa kliniki.
Lik'hemik'hale tse ngata tsa lijo li ntse li hlahlojoa ka hohle kamoo ho ka khonehang li-AGE inhibitors. Ka mohlala, lithuto tsa khale li bontša hore quercetin (e fumanoang capers, eiee, cranberries le liapole), likatechine (ka tala e tala), le resveratrol (ka morara o mofubelu, blueberries, veine e khubelu le chokolete e lefifi) e ka thibela li-AGE. Ho qoba lijo tse holimo lilemong tsa li-AGE ho ka boela ha tsamaea ka tsela e telele.
Lisebelisoa:
> Alkhalaf A, Kleefstra N, Groenier KH, et al. Phello ea benfotiamine ho qetellong ea glycation endproducts le likarolo tsa endothelial ho se sebetse le ho ruruha ka lefu la tsoekere nephropathy. PLoS One. 2012; 7 (7): e40427.
> Alkhalaf A, Klooster A, van Oeveren W, et al. Tlhahlobo ea kliniki e laoloang ka makhetlo a mabeli a foufetseng, a hlophisitsoeng, a laoloang ke li-benfotiamine ho bakuli ba nang le lefu la tsoekere la tsoekere. Tlhokomelo ea lefu la tsoekere. 2010 Jul; 33 (7): 1598-601.
> Fraser DA, Diep LM, Hovden IA, le al. Litla-morao tsa nako e telele ea molomo oa benfotiamine e tlatsetsoang meleng ea methapo ea meriana le ea ho ruruha ho bakuli ba nang le lefu la tsoekere la mofuta oa 1: teko e laoloang ka likhoeli tse 24, tse peli tse foufetseng, tse sa hlophisitsoeng, tse laoloang ke placebo. Tlhokomelo ea lefu la tsoekere. 2012 May; 35 (5): 1095-7.
> Pan X, Chen Z, Fei G, le al. Ntlafatso ea nako e telele ea ts'ebeliso ea kelello Kamora 'Muso oa Benfotiamine ho bakuli ba nang le mafu a Alzheimer's. Neurosci Bull. 2016 Dec; 32 (6): 591-596.
> Boikarabello: Boitsebiso bo boletsoeng sethaleng sena bo reretsoe merero ea thuto feela 'me ha bo nkele sebaka keletso, ho hlahlojoa kapa kalafo ke ngaka e nang le tumello. Ha e reretsoe ho koahela mekhoa eohle ea tlhokomelo, likamano tsa lithethefatsi, maemo kapa liphello tse bohloko. U lokela ho batla thuso ea meriana hang-hang bakeng sa bophelo bo botle le ho buisana le ngaka pele u sebelisa mefuta e meng ea phekolo kapa u etse phetoho tsamaisong ea hau.