Lumbrokinase ke enzyme e nkiloeng ho Lumbricus rubellus, mofuta oa limela tsa lefatše. E rekisoa ka fomeng ea lijo tsa lijo, e hlalosoa e le enzyme ea fibrinolytic (ntho e khothalletsang ho senyeha ha fibrinogen, protheine e amehang ho thehoa ha mali). Ho tlatsetsoa ka lumbrokinase ho nahanoa hore ho fana ka melemo e 'maloa ea bophelo bo botle, ho kenyeletsa ho ntlafatsa bophelo bo botle ba pelo le ho thusa tšireletso ea lipelo ka ho loantša mali.
Lisebelisoa
Baeletsi ba bontša hore lumbrokinase e ka thusa ka maemo a latelang a bophelo bo botle:
Melemo
Ho fihlela joale, lipatlisiso ka liphello tsa bophelo bo botle ba lumbrokinase li lekane. Leha ho le joalo, ho na le bopaki bo bong ba hore bo bontša tšepiso ea ho phekoloa ha maemo a itseng. Mona ho sheba liphuputso tse 'maloa ka melemo e ka' nang ea e-ba teng:
1) Bophelo ba pelo
Lumbrokinase e ka thusa ho phekola angina, ho ea ka phuputso e qalileng e phatlalalitsoeng ho Journal of Alternative and Complementary Medicine ka 2009. Bakeng sa thuto, bafuputsi ba fane ka batho ba 10 ba nang le lefu la pelo le angina khoeling e le 'ngoe ea phekolo le lumbrokinase (ho phaella moo ho tlhokomelo ea bona e tloaelehileng). Qetellong ea thuto, matšoao a angina a ile a ntlafala ho bakuli ba tšeletseng ho ba leshome.
Ho phaella moo, tlhahlobo ea pele e phatlalalitsoeng koranteng ea Sechaena ea Acta Pharmaceutica Sinica ka 2006 e fumane hore lumbrokinase e ka sireletsa pelo ea pelo.
Litlhahlobo ho likhoto, bangoli ba thuto ba entse qeto ea hore lumbrokinase e ka sireletsa khahlanong le myocardial ischemia (boemo bo tšoaetsoeng ke ho thibela methapo ea mali le ho fokotsa ho phalla ha mali ho ea pelong).
2) Stroke
Lipatlisiso tsa pele li bontša hore lumbrokinase e ka thusa ho thibela ho otloa ke lefu. Ka thupelo ea 2013 e phatlalalitsoeng ka Chinese Medical Journal , ka mohlala, batho ba 310 ba kenngoa sepetlele ka ho otloa ke lefu la kelello (mofuta oa ho otloa ha lefu nakong ea ha mokokotlo oa boko bo koetsoe) ba ne ba phekoloa kalafo e tloaelehileng ea meriana kapa kalafo e tloaelehileng hammoho le capsules ea lumbrokinase e le 'ngoe selemo.
Qetellong ea thuto, sehlopha se fumanang phekolo ea lumbrokinase se ne se e-na le lichapo tse seng kae tsa kemik'hale.
Phuputsong ea 2008 e tsoang Europe Journal of Pharmacology , liteko tsa lisele tsa motho li ile tsa etsa qeto ea hore lumbrokinase e ka thusa ho lebela ho ba le masapo a senyesemia. (Boemo bo tšoaetsoeng ke phekolo ea mali e sa lekaneng ho ea bokoeng, cerebral ischemia e ka fokotsa phepelo ea oksijene ea boko 'me hape e baka ho otloa.) Phuputso eo e fumane hore lumbrokinase e ka' na ea loantša masapo a cerebral ischemia ka karolo e itseng ka ho thibela ho thehoa ha mali.
Ho phaella moo, phuputso e nyenyane e phatlalalitsoeng ho Clinical Hemorheology le Microcirculation ka 2000 e fumane hore lumbrokinase e ka ba molemo ho phekola lefu la cerebral infarction (mofuta oa pholiso ea ischemic e bakoang ke ho thehoa ha mali ka har'a boko).
Bakeng sa thuto, batho ba 31 ba tšoeroeng ke lefu la cerebral infarction ba ne ba tšoaroa ka lumbrokinase, ha bakuli ba bang ba 20 ba abeloa sehlopha sa taolo. Liphello li bonts'itse hore lumbrokinase e ka thusa ho tšoara lesapo la 'mele ka karolo e itseng ka ho fokotsa fibrinogen.
3) Lefu la tsoekere
Phuputso e entsoeng ke liphoofolo e phatlalalitsoeng ka lefu la tsoekere le lits'ebetso tsa meriana ka 2013 e fana ka maikutlo a hore lumbrokinase e ka thusa ho loantša nefropathy ea lefu la tsoekere (boemo ba liphio bo bakoang ke ho laola bokooa ba lefu la tsoekere le khatello ea mali ).
Ha ho etsoa liteko tsa litoeba tsa lefu la tsoekere, bo-rasaense ba hlokometse hore phekolo e nang le lumbrokinase e thusitse ho sireletsa khahlanong le lefu la tsoekere la likokoana-hloko (mohlomong ka ho ama likokoana-hloko tse ling tse nahanoang hore li phetha karolo ea ho senyeha ha liphio tse amanang le boemo bona).
Liphello tse ka khonehang
Kaha liphuputso tse seng kae hakaalo li lekile liphello tsa lumbrokinase bathong, ho potlakile ho bolela hore na lumbrokinase e sireletsehile bakeng sa nako e telele kapa e sebelisoang hangata. Bakhachane, bo-'mè ba tlhokomelo, le bana ha baa lokela ho nka lumbrokinase.
Hape ho na le ho ameha ka hore lumbrokinase e ka baka litla-morao tse 'maloa, ho akarelletsa ho nyefoloa, ho senya, letšollo, ho phatloha ha letlalo, le ho itšoara hantle.
Kaha ho boleloa hore lumbrokinase e senya fibrinogen (e leng ho hlokahalang hore ho thehoe mali), ho ka etsahala hore ebe tlatsetso e ka kena-kenana le mokhoa o tloaelehileng oa ho thibela mali le ho lebisa ho tsoa mali.
Batho ba nang le maemo a amanang le kotsi e eketsehileng ea ho tsoa madi ha baa lokela ho nka lumbrokinase. Ha ea lokela ho nkoa pele ho buuoa kapa ho latela opereishene e latelang. Hape ha ea lokela ho nkoa ka meriana, li-supplement, kapa litlama tse nang le tšusumetso ea mali.
Ke habohlokoa ho hopola hore lisebelisoa ha li e-s'o hlahlojoe polokeho le lijo tse ling tsa lijo tse ngata li sa tsamaisoe ka molao. Litlhahiso tse ling ke tsa ho sebelisa lisebelisoa tsa lijo tse sireletsehileng.
The Bottom Line
Le hoja lipatlisiso tsa pele li thahasella, ho na le ho hloka liteko tse kholo tsa likliniki-mofuta oa lipatlisiso tseo u batlang ho li bona ho kenya lihlahisoa tse feletseng kalafo-e tiisang liphello tsena. Haeba u ntse u nahana ho e sebelisa, ke habohlokoa hore u etele ngaka ea hau ho buisana le hore na e nepahetse ebile e sireletsehile ho uena le ho lekanya melemo le boiketlo. Lumbrokinase ha ea lokela ho sebelisoa sebakeng sa phekolo e tloaelehileng bakeng sa maemo a kang angina kapa stroke.
Bakeng sa thuso ho fokotsa kotsi ea lefu la hao, ke habohlokoa ho laola khatello ea mali ea hau le k'holeseterole, latela mokhoa o nepahetseng oa ho ja, ho ikoetlisa kamehla le ho qoba ho tsuba. Liphuputso tse ling li bontša hore batho ba jang tee e tala, tee e ntšo le omega-3 fatty acids ba ka 'na ba e-ba le kotsing e fokotsehileng ea ho otloa ke stroke.
Lisebelisoa:
> Cao YJ, Zhang X, Wang WH, le al. Oral fibrinogen-depleting agent agent lumbrokinase bakeng sa ho thibela lefu la ho otloa ke lefu la sethoathoa: liphello tse hlahang nyeoeng e mengata, e khetholloang, e tsamaisanang le lits'oaelo. Chin Med J (Engl). 2013 Nov; 126 (21): 4060-5.
> Ji H, Wang L, Bi H, et al. Mekhoa ea lumbrokinase e sireletsang boloetse ba masapo. Eur J Pharmacol. 2008 Aug 20; 590 (1-3): 281-9.
Jin L, Jin H, Zhang G, Xu G. Liphetoho ka ho kopanya le lisele tsa plasminogen ka mor'a ho phekoloa ha masapo a pelo le lumbrokinase. Clin Hemorheol Microcirc. 2000; 23 (2-4): 213-8.
Kasim M, Kiat AA, Rohman MS, Hanifah Y, Kiat H. Ntlafatso ea perfusion ea myocardial ka angina pectoris e tsitsitseng ka lumbrokinase ea molomo: thuto ea lifofane. J Molemo o mong oa tlatsetso. 2009 May; 15 (5): 539-44.
Sun H, Ge N, Shao M, Cheng X, Li Y, Li S, Shen J. Lumbrokinase e thibela lefu la tsoekere la diabetes ka ho laola ho tlosoa ha metlakollar matrix ho tswa ho likhoto tsa lefu la tsoekere la Streptozotocin. Diabetes Res Clin Pract. 2013 Apr; 100 (1): 85-95.
Taba e nepahetseng: Boitsebiso bo boletsoeng setšeng sena bo reretsoe merero ea thuto feela 'me ha bo nkele sebaka keletso, ho hlahlojoa kapa kalafo ke ngaka e nang le tumello. Ha e reretsoe ho koahela mekhoa eohle ea tlhokomelo, likamano tsa lithethefatsi, maemo kapa liphello tse bohloko. U lokela ho batla thuso ea meriana hang-hang bakeng sa bophelo bo botle le ho buisana le ngaka pele u sebelisa mefuta e meng ea phekolo kapa u etse phetoho tsamaisong ea hau.